The olfactory system mediates the sense of smell. In many animals, olfaction is critical for food location, predator avoidance, individual recognition, as well as social and sexual behaviors that are crucial for the survival of the species. As a model, the mouse olfactory system combines powerful genetics, accessibility, and behavioral relevance, allowing one to address fundamental questions in neurobiology.
The laboratory is currently investigating how the organization of inputs to the olfactory bulb of the brain contributes to odor perception and innate behavior. To do this, we use a variety of methods including mouse molecular genetics, gene expression profiling, optical imaging, optogenetics, electrophysiology and behavior.