Acellular Dermal Matrix Allograft Used Alone and in Combination with Enamel Matrix Protein in Gingival Recession: Histologic Study in Dogs
Cristiane Aparecida de Oliveira, PhD / Luís Carlos Spolidório, PhD / Joni Augusto Cirelli, PhD / Rosemary Adriana Chiérici Marcantonio, PhD
Gingival recession was created in six mongrel dogs. The dogs were divided into two groups based on treatment: group 1—AlloDerm only, group 2—AlloDerm + Emdogain. The histologic results were compared. At the end of the study, the mean values were, for groups 1 and 2, respectively: 0.06 and 0.32 mm for cementum regeneration; –0.75 and –0.86 mm for bone regeneration; –2.15 and –3.11 mm for attachment level; and 4.90 and 5.51 mm for defect extent. The epithelial formation parameter was 2.88 mm in group 1 and 2.15 mm in group 2, which was a statistically significant difference. It could be concluded that Emdogain did not result in beneficial effects when associated with AlloDerm.
(Int J Periodontics Restorative Dent 2005;25:595–603.)