Therese M Pham
Affiliation: Karolinska Institutet
- Intermittent individual housing increases survival of newly proliferated cellsElin Aberg
Department of Neuroscience, Karolinska Institute, 171 77 Stockholm, Sweden
Neuroreport 16:1419-22. 2005..Thus, changes in housing conditions on every second day can, under certain circumstances, have an impact on the survival of newly proliferated cells in the dentate gyrus...
- Environmental influences on brain neurotrophins in ratsTherese M Pham
Department of Clinical Neuroscience, Occupational Therapy, Elderly Care Research, Division of Geriatric Medicine, Karolinska Institutet, Huddinge University Hospital, S 141 86 Huddinge, Sweden
Pharmacol Biochem Behav 73:167-75. 2002..Because neurotrophic factors are essential for neural development and survival, they are likely to be involved in the cerebral consequences modified by enriched experiences...
- Cognitive impairment in the Tg6590 transgenic rat model of Alzheimer's diseaseEwa Kloskowska
Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Stockholm, Sweden
J Cell Mol Med 14:1816-23. 2010..The Tg6590 transgenic rat line should prove a suitable model of early AD for advanced studies including serial cerebrospinal fluid sampling, electrophysiology, neuroimaging or complex behavioural testing...
- Neurotrophin levels and behaviour in BALB/c mice: impact of intermittent exposure to individual housing and wheel runningShun Wei Zhu
Division of Experimental Geriatrics, Department of Neurotec, Karolinska University Hospital, Karolinska Institute, Stockholm 141 86, Sweden
Behav Brain Res 167:1-8. 2006..Our results also suggest that some changes in neurotrophin levels induced by intermittent individual housing are not similar to those caused by continuous individual housing...
- Behavioral assessment of intermittent wheel running and individual housing in mice in the laboratoryTherese M Pham
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
J Appl Anim Welf Sci 8:157-73. 2005..Intermittent withdrawal of individual housing affects the animals more than other commodities. Wheel running normalizes some effects of intermittent separation from the enriched, social home cage...
- Nogo receptor 1 regulates formation of lasting memoriesAlexandra Karlén
Department of Neuroscience, Karolinska Institutet, Retzius vag 8, 171 77 Stockholm, Sweden
Proc Natl Acad Sci U S A 106:20476-81. 2009..Understanding the molecular underpinnings of synaptic rearrangements that carry lasting memories may facilitate development of treatments for memory dysfunction...
- Transgenic overexpression of interleukin-1 receptor antagonist in the CNS influences behaviour, serum corticosterone and brain monoaminesMircea Oprica
Division of Experimental Geriatrics, Neurotec Department, Karolinska Institutet, Novum, KFC, 4th Floor, Karolinska University Hospital, Huddinge, SE 141 86 Stockholm, Sweden
Brain Behav Immun 19:223-34. 2005..Finally, the activation of hypothalamo-pituitary-adrenal (HPA)-axis was comparable in the two genotypes, however Tg hsIL-1ra(+/+) mice had a modified metabolism of brain monoamines as compared to WT mice...
- Selective nicotinic receptor consequences in APP(SWE) transgenic miceIvan Bednar
Divisions of Molecular Neuropharmacology, Occupational Therapy and Elderly Care Research NEUROTEC, S 141 86 Stockholm, Sweden
Mol Cell Neurosci 20:354-65. 2002..The upregulation of the nAChRs probably reflects compensatory mechanisms in response to Abeta burden in the brains of Tg+ mice...