Histopathological analysis of both eyes showed identical changes. The corneal endothelial cells were intact. There was no inflammation in the anterior chamber, iris, choroid, optic nerve, or sclera (Figure 1), confirmed by immunohistochemistry using markers for T and B lymphocytes (CD3, CD5, CD43, and L26) and histiocytes (CD68) (Figure 2). All of the retinal layers were morphologically normal without inflammation, degeneration, extensive apoptosis (Figure 1), or necrosis as confirmed by caspase 3, glial fibrillary acidic protein, and vimentin immunostain. The retinal vessels extended to medium zone 2 of the retina as shown by CD31, CD34, and factor VIII antibodies (Figure 2). Few vascularization tufts through the internal limiting membrane into the vitreous were seen at the junction posterior and medium zone 2, some surrounded by histiocytes (Figure 2), but no preretinal fibrovascular membrane was seen and vascularization had proceeded anteriorly. Expression of VEGF in the retina and other ocular tissues was detected at both protein and messenger RNA levels (Figure 2).