- Tumor targeting by an aptamerBrian J Hicke
NeXstar Pharmaceuticals, Boulder, Colorado, USA
J Nucl Med 47:668-78. 2006..Aptamers are small oligonucleotides that are selected to bind tightly and specifically to a target molecule. We sought to determine whether aptamers have potential for in vivo delivery of radioisotopes or cytotoxic agents...
- A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichmentDion A Daniels
Gene Expression and Protein Biochemistry, GlaxoSmithKline Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, England
Proc Natl Acad Sci U S A 100:15416-21. 2003..Systematic evolution of ligands by exponential enrichment appears to be a successful strategy for the a priori identification of targets of biological interest within complex systems...