over a year ago:
Hmmm...I wonder if it might possibly be her father's wife that dies? I guess it's because they just started growing close but I can't really see what the writers can do with that relationship, so why not make it dramatic and make Meredith lose both her birth mother and her new step mother.
As for Callie leaving, I can see that happening too since George and Izzie obviously have something going on and Callie seems to be getting the short end of the stick, I can't imagine she would stay if she breaks things off with George, that would just be too awkward. I'm sure the new private practice that Addison is going to could use a hot orthopedic surgeon!