The real significance that I have found is in the self-reflecting integrated fractal-like patterns we see in the Biblical Holographs. For example, the Shema, the declaration of God's Unity, has a fourfold nested structure based on the value of its central claim:
Echad (One) = 13
YHWH (The Lord) = 26 = 2 x 13
YHVH Echad (The Lord is One) = 39 = 3 x 13
Sum of Shema = 1118 = 13 (Echad) x 86 (Elohim) = ONE X GOD
I talk about this in my article called The Unity Holograph.
All the holographs were designed by God upon the variations of the Centered Hexagonal and Star pairs. (Like the Star of David). For example, here is the Logos Holograph:
And most significantly, the Creation HyperHolograph that unites Genesis 1:1-5 and John 1:1-5: