Summary: A subspecialty of pathology applied to the solution of clinical problems, especially the use of laboratory methods in clinical diagnosis. (Dorland, 28th ed.)
Publications213 found, 100 shown here
- Measuring the significance of participant evaluation of acceptability of cases in the College of American Pathologists Interlaboratory Comparison Program in cervicovaginal cytologyAndrew A Renshaw
Department of Pathology, Baptist Hospital of Miami, Miami, FL, USA
Arch Pathol Lab Med 129:1093-6. 2005..The quality of gynecologic cytology slides within educational and proficiency testing programs may deteriorate during use. Participant evaluation of the acceptability of these slides subsequent to possible deterioration is not known...
- Contributions of pathology and laboratory medicine to the patient safety movementNoubar Kessimian
Department of Pathology, Memorial Hospital of Rhode Island, Pawtucket 02860, USA
Med Health R I 88:216-9. 2005
- Specimen labeling errors: a Q-probes analysis of 147 clinical laboratoriesElizabeth A Wagar
Department of Pathology and Laboratory Medicine, University of California Los Angeles Clinical Laboratories, Los Angeles, CA 90095 1732, USA
Arch Pathol Lab Med 132:1617-22. 2008..Specimen identification errors have been reported to occur at rates of 0.1% to 5%...
- Application of traditional clinical pathology quality control techniques to molecular pathologyShu Ling Liang
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Mol Diagn 10:142-6. 2008..kit-based assays, and the desire to provide the highest quality clinical data, we began applying traditional clinical pathology quality control tools to the molecular diagnostics laboratory...
- Clinical pathology testing recommendations for nonclinical toxicity and safety studies. AACC-DACC/ASVCP Joint Task ForceK Weingand
Procter and Gamble Co, Miami Valley Laboratories, Cincinnati, Ohio 45239
Toxicol Pathol 20:539-43. 1992b>Clinical pathology testing in nonclinical toxicity and safety studies is an important part of safety assessment. In recent years, clinical laboratory testing has rapidly expanded and improved...
- Development and evaluation of the virtual pathology slide: a new tool in telepathologySean S P Costello
School of Biotechnology, Medical Informatics Group, Dublin City University, Dublin, Ireland
J Med Internet Res 5:e11. 2003..This permits a pathologist to navigate to any area on a slide, at any magnification, similar to a conventional microscope...
- Consensus report of the task force on standardisation of DNA flow cytometry in clinical pathology. DNA Flow Cytometry Task Force of the European Society for Analytical Cellular PathologyM G Ormerod
Department of Medical Radiobiology, Karolinska Institute, Stockholm, Sweden
Anal Cell Pathol 17:103-10. 1998Guidelines are given to assist the standardisation of DNA flow cytometry in clinical pathology. They have been agreed by a group of twelve scientists from nine European countries.
- Digital storage of glass slides for quality assurance in histopathology and cytopathologyFrancesca Demichelis
ITC irst, Telemedicine and Medical Informatics Laboratory, Trento, Italy
J Telemed Telecare 8:138-42. 2002..Use of virtual slides should encourage the diffusion of national quality assurance programmes, which at present suffer from certain organizational and logistical limitations...
- Application of virtual microscopy in clinical cytopathologyD M Steinberg
The John K. Frost Cytopathology Laboratory, Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland, USA
Diagn Cytopathol 25:389-96. 2001..Shortcomings include 1) expensive initial setup, 2) inability to maintain an adequate focus in a thick smear with multiple levels, 3) large storage size of the VM slide, and 4) relatively long time needed to scan a slide...
- Development of visual diagnostic expertise in pathology -- an information-processing studyRebecca S Crowley
Center for Pathology Informatics, Center for Biomedical Informatics, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
J Am Med Inform Assoc 10:39-51. 2003..To identify key features contributing to trainees' development of expertise in microscopic pathology diagnosis, a complex visual task, and to provide new insights to help create computer-based training systems in pathology...
- The impact of molecular diagnostic tests on patient outcomesJ S Ross
Department of Pathology and Laboratory Medicine, Albany Medical College, New York, USA
Clin Lab Med 19:815-31, vi-vii. 1999..In this review, the financial and patient care determinants of outcomes for molecular-based testing of disease predisposition, screening, early detection, and directed therapy are presented...
- Saliva and the clinical pathology laboratoryMichael A Pesce
Department of Pathology, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
Ann N Y Acad Sci 1098:192-9. 2007..These tests fall into multiple clinical pathology disciplines, including clinical chemistry, hematology, coagulation, transfusion medicine, microbiology, ..
- Resident physician opinions on autopsy importance and procurementMindy J Hull
Department of Pathology and Laboratory Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
Hum Pathol 38:342-50. 2007..Improving autopsy education, enhancing availability of resources, and strengthening the pathologist-internist collaboration may serve to heighten awareness and ultimately procurement...
- The integration of molecular diagnostics with therapeutics. Implications for drug development and pathology practiceJeffrey S Ross
Dept of Pathology and Laboratory Medicine, Albany Medical College, Albany, NY 12208, USA
Am J Clin Pathol 119:26-36. 2003....
- Automated clinical annotation of tissue bank specimensJohn R Gilbertson
Center for Pathology Informatics, Department of Pathology, Benedum Oncology Informatics Center, University Cancer Institute, University of Pittsburgh Medical School, 5150 Centre Avenue, Pittsburgh, PA 15232, USA
Stud Health Technol Inform 107:607-10. 2004..The result has been much more extensive and accurate initial tissue annotation with less effort in the tissue bank, as well as dynamic ongoing annotation as the cancer registry follows patients over time...
- Comprehensive graphic-based display of clinical pathology laboratory dataJohn Bernard Henry
Dept of Pathology, State University of New York, Upstate Medical University, 750 E Adams St, Syracuse, NY 13210, USA
Am J Clin Pathol 119:330-6. 2003..with clinician perception and ease of data interpretation in redesigning the graphic reporting of numeric clinical pathology laboratory data...
- Comparative genomic hybridization arrays in clinical pathology: progress and challengesShelly R Gunn
Department of Pathology, University of Texas Health Science Center, San Antonio, Texas 78229 3900, USA
Mol Diagn Ther 11:73-7. 2007..In this article, we share some of our experiences with diagnostic array CGH and discuss recent progress and challenges involved with the integration of array CGH into clinical laboratory medicine...
- The role of the pathologist as tissue refiner and data miner: the impact of functional genomics on the modern pathology laboratory and the critical roles of pathology informatics and bioinformaticsM J Becich
Center for Pathology Informatics, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center Health System, Pittsburgh, PA 15232, USA
Mol Diagn 5:287-99. 2000....
- The development and evaluation of the UK national telepathology networkW M Bamford
Department of Histopathology, Leicester Royal Infirmary, UK
Histopathology 42:110-9. 2003..Arguing that the value of a network increases as more people are connected, we sought to install a simple, low-cost telepathology system into any histopathology laboratory which requested it within the UK...
- Pathologists' attitudes to implementing telepathologyT Mairinger
Department of Pathology, University of Innsbruck, Austria
J Telemed Telecare 4:41-6. 1998..Teleteaching and teletraining were seen as welcome additional techniques, but were nevertheless judged unable to replace classical methods of teaching and training...
- Interlaboratory reproducibility of atypical squamous cells of undetermined significance report: a national surveyM Confortini
Analytical and Biomolecular Cytology Unit, Centro per lo Studio e la Prevenzione Oncologica, Florence, Italy
Cytopathology 14:263-8. 2003....
- The potential for failure in gynecologic regulatory proficiency testing with current slide validation criteria: results from the College of American Pathologists Interlaboratory Comparison in Gynecologic Cytology ProgramNancy A Young
Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Arch Pathol Lab Med 130:1114-8. 2006..Current regulatory proficiency testing scoring results in an automatic failure for identifying high-grade squamous intraepithelial lesion (HSIL) as negative...
- Errors in pathology and laboratory medicine: consequences and preventionSandra C Hollensead
Department of Pathology and Laboratory Medicine, University of Louisville SOM, Louisville, Kentucky 40202, USA
J Surg Oncol 88:161-81. 2004..Seven recommendations are made to reduce errors in future for Pathology and Laboratory Medicine...
- Robustness of validation criteria in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal CytologyAndrew A Renshaw
Department of Pathology, Baptist Hospital of Miami, Miami, Fla, USA
Arch Pathol Lab Med 130:1119-22. 2006..Although the precision of diagnoses in peer-reviewed educational programs has been examined, the robustness of the validation criteria for specific types of interpretations used in proficiency testing has not been previously studied...
- Leukemia/lymphoma in cerebrospinal fluid: distinguishing between cases that performed well and poorly in the College of American Pathologists Interlaboratory Comparison Program in Non-gynecologic CytologyAndrew A Renshaw
Department of Pathology, Baptist Hospital of Miami, Miami, Fla, USA
Arch Pathol Lab Med 130:1762-5. 2006..Although the cytologic features of leukemia/lymphoma in cerebrospinal fluid specimens are well known, the correlation of these features with the ability of cytologists to identify this tumor have not been well studied...
- Pap test discrepancies and follow-up histologyEdward B Stelow
Department of Pathology and Laboratory Medicine, University of Minnesota, Minneapolis, Minnesota 55415, USA
Diagn Cytopathol 29:111-5. 2003..This suggests that discrepancy data may be helpful for evaluating the performance of both CPs and CTs. It may also be of educational use for both CPs and CTs to know the follow-up histology in these cases...
- Cytologic features of squamous cell carcinoma in conventional smears: comparison of cases that performed poorly with those that performed well in the College of American Pathologists Interlaboratory Comparison Program in cervicovaginal cytologyAndrew A Renshaw
Department of Pathology, Baptist Hospital of Miami, Miami, FL 33176 2197, USA
Arch Pathol Lab Med 129:1097-9. 2005....
- Cytologic features of adenocarcinoma, not otherwise specified, in conventional smears: comparison of cases that performed poorly with those that performed well in the College of American Pathologists Interlaboratory Comparison Program in cervicovaginal cyAndrew A Renshaw
Department of Pathology, Baptist Hospital of Miami, Miami, FL 33176 2197, USA
Arch Pathol Lab Med 130:23-6. 2006....
- [Procedure for accurate evaluation of laboratory data and its international trends]Katsuhiko Kuwa
Graduate School of Comprehensive Human Sciences Institute of Clinical Medicine, University of Tsukuba, Tsukuba, 305 8575
Rinsho Byori 53:531-9. 2005..As the results, the work of the standardization based on reliability such as validation of reagent's kits and the measured values and uncertainty evaluation would be internationally advanced...
- Significance of field validation in the interlaboratory comparison program in cervicovaginal cytologyDwight K Oxley
Arch Pathol Lab Med 130:144; author reply 144-5. 2006
- Papanicolaou tests with mixed high-grade and low-grade squamous intraepithelial lesion features: distinct performance in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal CytopathologyAndrew A Renshaw
Department of Pathology, Baptist Hospital of Miami, Miami, FL, USA
Arch Pathol Lab Med 130:456-9. 2006..The performance of cases with mixed LSIL and HSIL features is unknown...
- Measuring the significance of field validation in the College of American Pathologists Interlaboratory Comparison Program in Cervicovaginal Cytology: how good are the experts?Andrew A Renshaw
Department of Pathology, Baptist Hospital of Miami, Miami, Fla, USA
Arch Pathol Lab Med 129:609-13. 2005..However, the reliability of expert opinion alone in selecting slides of a specific cytodiagnosis that can be reproducibly and reliably identified by subsequent reviewers has not been determined...
- Laboratory accreditation and inspectionCarol A Rauch
Department of Pathology, Baystate Health, 759 Chestnut Street, Springfield, MA 01199, USA
Clin Lab Med 27:845-58, vii. 2007....
- [How can we contribute to Yamagata University Hospital as clinical laboratory physicians?]Masahiko Igarashi
Department of Laboratory Medicine, Yamagata University School of Medicine, Yamagata 990 9585
Rinsho Byori 56:689-95. 2008..Therefore, our clinical laboratory physicians should play a central role to guarantee the specified health checkup system...
- Development and preliminary evaluation of the VPS ReplaySuite: a virtual double-headed microscope for pathologyDan J Johnston
Medical Informatics Group, School of Biotechnology, Dublin City University, Dublin, Ireland
BMC Med Inform Decis Mak 5:10. 2005..Limited emphasis has been placed on analysing the diagnostic process used by pathologists to reach a diagnosis and using this as a resource for improving diagnostic performance...
- Quality assurance in gynecologic cytology. The value of cytotechnologist-cytopathologist discrepancy logsE S Cibas
Dept of Pathology, Brigham and Women's Hospital, 75 Francis St, Boston, MA, USA
Am J Clin Pathol 115:512-6. 2001..Measures of CT-CP diagnostic concordance are a useful and efficient measure of CT performance and can be incorporated into mandatory semiannual performance evaluations...
- Cytopathology in SloveniaZ Pohar-Marinsek
Department of Cytopathology, Institute of Oncology, Zaloska, Ljubljana, Slovenia
Cytopathology 15:53-7. 2004..6/100 000 in the year 2000. The mortality rate has remained roughly constant at 5-7/100 000 for the last 20 years. During the last few years quality assurance measures have been taken for improving the performance in cervical cytology...
- Comparison of cytology proficiency testing: glass slides vs. virtual slidesMariBeth Gagnon
Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3724, USA
Acta Cytol 48:788-94. 2004..To compare proficiency testing in gynecologic cytology using glass slides vs. virtual slides...
- Assessment monitoring of laboratory critical values: a College of American Pathologists Q-Tracks study of 180 institutionsElizabeth A Wagar
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, 90095 1732, USA
Arch Pathol Lab Med 131:44-9. 2007..Critical laboratory value reporting is a highly visible and essential key activity for clinical laboratories...
- Overview of the laboratory accreditation programme of the College of American PathologistsK K Abu-Amero
Molecular Genetics and DNA Diagnostics Laboratory, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
East Mediterr Health J 8:654-63. 2002..This article gives an insight into the current situation of laboratory accreditation in Saudi Arabia and an updated overview of the process involved in obtaining laboratory accreditation from the College of American Pathologists...
- Improvements to the CAP Laboratory Accreditation ProgramR Bruce Williams
College of American Pathologists Commission on Laboratory Accreditation, USA
Clin Leadersh Manag Rev 20:E4. 2006
- The Indonesian society of clinical pathologist external quality assessment program (ISCP-EQAP) in clinical chemistryM Suryaatmadja
Department of Clinical Pathology, Faculty of Medicine University of Indonesia, Dr Cipto Mangunkusmo General Hospital, Jakarta, Indonesia
Southeast Asian J Trop Med Public Health 33:44-5. 2002
- Speak out for quality pathology and laboratory medicineDavid F Keren
Am J Clin Pathol 122:314. 2004
- [CAP quality management system in clinical laboratory and its issue]Hiromitsu Tazawa
SBS, Inc, Sagamihara 229 1125
Rinsho Byori 52:266-9. 2004....
- Detecting and preventing the occurrence of errors in the practices of laboratory medicine and anatomic pathology: 15 years' experience with the College of American Pathologists' Q-PROBES and Q-TRACKS programsDavid A Novis
Department of Pathology, Wentworth Douglass Hospital, Dover, NH 03820, USA
Clin Lab Med 24:965-78. 2004....
- Review of Penner's criteria for proficiency testing in cytopathology: implications for the redesign of the federally mandated proficiency testing in cytopathologyGeorge K Nagy
Division of Molecular Medicine, Cytopathology Laboratory, Wadsworth Center, New York State Department of Health, Empire State Plaza, Albany, New York 12201 0509, USA
Diagn Cytopathol 35:61-4. 2007..The revised criteria should be taken into consideration in the planned technical redesign of the nationwide PTC...
- Interobserver agreement on microfollicles in thyroid fine-needle aspiratesAndrew A Renshaw
Department of Pathology, Baptist Hospital of Miami, Miami, FL 33176 2197, USA
Arch Pathol Lab Med 130:148-52. 2006..Although microfollicles are a well-known feature of follicular neoplasms in fine-needle aspirates of the thyroid, the level of agreement about classifying groups as microfollicles is not known...
- Q-tracks: a College of American Pathologists program of continuous laboratory monitoring and longitudinal trackingRichard J Zarbo
Department of Pathology, Henry Ford Hospital, Detroit, Mich 48202, USA
Arch Pathol Lab Med 126:1036-44. 2002....
- Assessment of interlaboratory variation in the immunohistochemical determination of estrogen receptor status using a breast cancer tissue microarrayRobin L Parker
Department of Pathology, Vancouver Hospital and University of British Columbia, Canada
Am J Clin Pathol 117:723-8. 2002..The tissue microarray was an efficient and effective tool for identifying variability in ER reporting and should prove valuable in other external quality assurance programs...
- Testing in cervicovaginal cytologyLeopold G Koss
Arch Pathol Lab Med 130:13. 2006
- Morphologic spectrum of papillary carcinoma of the thyroid: role of cytology in identifying the variantsSanjay Gupta
Division of Cytopathology, Institute of Cytology and Preventive Oncology, New Delhi, India
Acta Cytol 48:795-800. 2004..To evaluate the efficacy of fine needle aspiration cytology (FNAC) in the diagnosis of morphologic variants of papillary carcinoma of the thyroid (PCT) and to determine the reasons for misdiagnosis in discrepant cases on cytology...
- Nodal stage classification for breast carcinoma: improving interobserver reproducibility through standardized histologic criteria and image-based trainingRoderick R Turner
Department of Pathology, Saint John s Health Center, 1328 Twenty Second St, Santa Monica, CA 90404, USA
J Clin Oncol 26:258-63. 2008..We sought to determine whether a set of clearly defined histologic criteria could lead to reproducible nodal classification by pathologists...
- Interpretive disparity among pathologists in breast sentinel lymph node evaluationCory A Roberts
Department of Pathology, St Paul University Hospital and University of Texas Southwestern Medical Center, Dallas, TX, USA
Am J Surg 186:324-9. 2003..Immunohistochemical staining on breast sentinel lymph nodes (SLN) is controversial...
- Misinterpretation of normal cellular elements in fine-needle aspiration biopsy specimens: observations from the College of American Pathologists Interlaboratory Comparison Program in Non-Gynecologic CytopathologyNancy A Young
Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Arch Pathol Lab Med 126:670-5. 2002..Data generated from this program allow tracking pathologist performance in a wide variety of laboratory practices...
- Identification errors involving clinical laboratories: a College of American Pathologists Q-Probes study of patient and specimen identification errors at 120 institutionsPaul N Valenstein
Department of Pathology, St Joseph Mercy Hospital, Ann Arbor, Mich 48106 0998, USA
Arch Pathol Lab Med 130:1106-13. 2006..Misidentified laboratory specimens may cause patient injury, but their frequency in general laboratory practice is unknown...
- A new era for the Pap testE B Holladay
Center for Quality Improvement in Gynecologic Cytopathology, Cytotechnology Program, Medical University of South Carolina, Charleston, USA
JAAPA 14:53-6. 2001..This relatively simple collection system will allow significant advances in molecular epidemiology and, in the future, development of a molecular Pap test...
- Image quality issues in a static image-based telepathology consultation practiceBruce H Williams
Department of Telepathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
Hum Pathol 34:1228-34. 2003..A review of common image deficiencies in static-image telepathology and possible causes is presented...
- Altered recognition of reparative changes in ThinPrep specimens in the College of American Pathologists Gynecologic Cytology ProgramTamela M Snyder
Department of Pathology, The Methodist Hospital, Houston, Tex, USA
Arch Pathol Lab Med 129:861-5. 2005..It is unknown whether cytologists recognize reparative changes in ThinPrep specimens as well, or less often, as in conventional smears...
- A regional centralized microbiology service in Calgary for the rapid diagnosis of malariaDeirdre L Church
Calgary Laboratory Services, Calgary, Alberta, Canada T3C 0J5
Arch Pathol Lab Med 127:687-93. 2003..A regional centralized laboratory service for the rapid diagnosis of malaria was implemented 3 years ago in May 1999 within the Division of Microbiology, Calgary Laboratory Services...
- Establishment of a central laboratory serum tumor marker service on a consolidated immunodiagnostic platform: development of practice standards, service improvements, and operational efficiencyPatrick M Sluss
Department of Pathology and Laboratory Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
Clin Leadersh Manag Rev 18:25-31. 2004..Over the past decade, serum tumor marker testing in patient management has become more defined, resulting in increasing test volume and wider availability of assays on automated immunodiagnostic platforms...
- Clinical pathology accreditation: standards for the medical laboratoryD Burnett
Lindens Lodge, Bradford Place, Penarth CF64 1LA, UK
J Clin Pathol 55:729-33. 2002This article describes a new set of revised standards for the medical laboratory, which have been produced by Clinical Pathology Accreditation (UK) Ltd (CPA)...
- Emerging concepts of quality assurance in clinical laboratoriesSumera Naz
Central Research Centre, Pakistan Medical Research Council, NIH, Islamabad
J Pak Med Assoc 56:412-4. 2006..Quality improvement in the modern clinical laboratory environment entails the continuous inspection and refinement of processes to ensure the efficient delivery of services that meet the needs and expectations of those who use them...
- Prostatic pathology reporting in the UK: development of a national external quality assurance schemeP Harnden
Cancer Research UK Clinical Centre, St James s University Hospital, Leeds, UK
Histopathology 52:147-57. 2008....
- Longitudinal evaluation of interobserver and intraobserver agreement of cervical intraepithelial neoplasia diagnosis among an experienced panel of gynecologic pathologistsBing Cai
Department of Epidemiology, Merck and Co, Inc, North Wales, PA 19454 1099, USA
Am J Surg Pathol 31:1854-60. 2007..These data indicate that the interpretation of histologic end points used in the quadrivalent vaccine clinical trial program is highly valid and reliable...
- [From the perspective of a clinical laboratory physician]Hiroshi Yoshida
Department of Clinical Laboratory Medicine, Fukushima Medical University School of Medicine, Fukushima 960 1247
Rinsho Byori 53:1155-8. 2005..Laboratory physicians and technologists should pay more attention to laboratory tests being performed by examinees and outpatients themselves, and participate more in improving and evaluating the usefulness of these tests...
- Patient safety in the clinical laboratory: a longitudinal analysis of specimen identification errorsElizabeth A Wagar
University of California, Los Angeles, Clinical Laboratories, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Box 951732, AL 206 CHS 10833 Le Conte Ave, Los Angeles, CA 90095 1732, USA
Arch Pathol Lab Med 130:1662-8. 2006....
- [From sample to report, a process analysis: presentation of two programmes for the improvement of professional practices, prepared by AFAQAP in partnership with HAS]Dominique Henin
Service d Anatomie Pathologique, AP HP, CHU Bichat Claude Bernard, 46 rue Henri Huchard, 75877 Paris Cedex 18
Ann Pathol 25:417-9. 2005
- A discussion of cases in the 2001 RCPA-AQAP Chemical Pathology Case Report Comments ProgramEe Mun Lim
Department of Biochemistry, Royal Perth Hospital, GPO Box X2213, PathCentre, Perth, WA 6847, Australia
Pathology 35:145-50. 2003....
- Critical values in anatomic pathology: how do we communicate?Virginia A LiVolsi
Am J Clin Pathol 122:171-2. 2004
- Accuracy of send-out test ordering: a College of American Pathologists Q-Probes study of ordering accuracy in 97 clinical laboratoriesPaul N Valenstein
Department of Pathology, St Joseph Mercy Hospital, 5301 E Huron River Dr, Ann Arbor, MI 48106 0995, USA
Arch Pathol Lab Med 132:206-10. 2008..Errors entering orders for send-out laboratory tests into computer systems waste health care resources and can delay patient evaluation and management...
- The laboratory and patient safetyElizabeth A Wagar
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, 10833 Le Conte Road, Los Angeles, CA 90095, USA
Clin Lab Med 27:909-30, viii-ix. 2007..Emerging ideas on identifying and reducing laboratory errors, as well as specific strategies are reviewed and discussed with examples...
- Trends in blood culture contamination: a College of American Pathologists Q-Tracks study of 356 institutionsLeonas G Bekeris
Phoenixville Hospital Laboratory, Phoenixville, PA 19460, USA
Arch Pathol Lab Med 129:1222-5. 2005..Blood culture contamination extends hospital stays and increases the cost of care...
- Five-year follow-up of routine outpatient test turnaround time: a College of American Pathologists Q-Probes studyPaul Valenstein
Department of Pathology, St Joseph Mercy Hospital, Ann Arbor, Mich 48106 0995, USA
Arch Pathol Lab Med 127:1421-3. 2003..Timely reporting of outpatient tests can increase efficiency of care and improve customer satisfaction...
- Effects of carbon dioxide inhalation on hematology, coagulation, and serum clinical chemistry values in ratsG L Walter
MPI Research, Mattawan, Michigan, USA
Toxicol Pathol 27:217-25. 1999..These alterations reiterate the importance of comparing clinical pathology values to those of concurrent control groups that have experienced blood collection under identical ..
- Clinical pathology in the National Toxicology ProgramM B Thompson
National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709
Toxicol Pathol 20:484-8; discussion 488-9. 1992The National Toxicology Program (NTP) developed a standard approach for clinical pathology investigations that was integrated into most toxicity studies designed and conducted after 1986...
- Effects of sensitization to dinitrochlorobenzene (DNCB) on clinical pathology parameters and mitogen-mediated blastogenesis in cynomolgus monkeys (Macaca fascicularis)P J Bugelski
Department of Experimental Pathology, SmithKline Beecham Pharmaceuticals, King of Prussia, Pennsylvania 19406 0939
Toxicol Pathol 18:643-50. 1990..The WBC parameters remained within the normal range and returned to pre-sensitization values at the later intervals.(ABSTRACT TRUNCATED AT 250 WORDS)..
- Clinical pathology: preanalytical variation in preclinical safety assessment studies--effect on predictive value of analyte testsJ H Riley
Department of Toxicology and Pathology, Hoffmann La Roche, Inc, Nutley, New Jersey 07110
Toxicol Pathol 20:490-500. 1992..Predictive value (likelihood of actual disease) of appropriate clinical pathology tests in toxicology is inversely dependent on preanalytical variation: uncontrolled variation produces data ..
- Evaluation of the renal effects of an antisense phosphorothioate oligodeoxynucleotide in monkeysD K Monteith
Isis Pharmaceuticals, Carlsbad, California 92008, USA
Toxicol Pathol 27:307-17. 1999..or an escalating dose regimen of 3, 10, 40, and 80 mg/kg of ISIS 2105 and were then evaluated for changes in clinical pathology indices, urinalysis parameters, and renal histopathology...
- Clinical pathology testing regulatory concernsJ Kanno
Department of Pathology, Faculty of Medicine, Tokyo Medical and Dental University, Japan
Toxicol Pathol 20:534-7. 1992..This situation will generate at least 2 practical problems in clinical pathology testing: (1) how to preselect test items without precise knowledge of toxicity endpoints and (2) how to ..
- Present status of animal clinical pathology examinations in the Japanese Pharmaceutical Manufacturers AssociationT Matsuzawa
Safety Research Laboratories, Yamanouchi Pharmaceutical Co, Ltd, Tokyo, Japan
Toxicol Pathol 20:528-33. 1992This paper will review the current status of animal clinical pathology in Japan using data obtained during a survey conducted by the Japanese Pharmaceutical Manufacturers Association (JPMA)...
- The measurement of renal injuryW F Loeb
Ani Lytics Inc, Gaithersburg, Maryland 20877, USA
Toxicol Pathol 26:26-8. 1998..Selection from a battery of clinical pathology tests allows the sensitive and specific measurement of renal dysfunction and injury...
- Laboratory turnaround time does not affect emergency department length of stayPetrie M Rainey
Am J Clin Pathol 127:154; author reply 154-5. 2007
- [110th anniversary of the death of the physician and patriot Vilém Dusan Lambl (1824-1895)]J Kilian
Stomatologická klinika LF UK a FN, Plzen
Cas Lek Cesk 144:847-8. 2005
- Founders of pediatric pathology: Marie Valdés-DapenaM Daria Haust
Department of Pathology, The University of Western Ontario, London, Canada, and Tampa General Hospital, FL 33601, USA
Pediatr Dev Pathol 9:345-52. 2006
- Appropriate use of clinical microbiology testsMichael L Wilson
Department of Pathology and Laboratory Services, Denver Health Medical Center, Department of Pathology, University of Colorado School of Medicine, Denver, CO, USA
Clin Lab Med 22:491-503. 2002..The real opportunities will come when there are scientifically and medically sound definitions of appropriate test use that can be used to change test use and improve patient care in a cost-effective way...
- National survey on critical values reporting in a cohort of Italian laboratoriesGiuseppe Lippi
Sezione di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico Biomediche, Universita degli Studi di Verona, Verona, Italy
Clin Chem Lab Med 45:1411-3. 2007..Critical values' reporting is an essential requisite for clinical laboratories. Local policies were investigated within an indicative cohort of Italian laboratories to monitor the situation and establish a performance benchmark...
- Rokitansky and his first description of polyarteritis nodosaVladimir Tesar
1st Department of Medicine, 1st Medical Faculty, Charles University, Prague, Czech Republic
J Nephrol 17:172-4. 2004..Karl Rokitansky, Professor of Pathology at the University of Vienna described polyarteritis nodosa in 1852 in a 23 year old man with a 5-day history of fever and diarrhoea...
- Integration of scanned document management with the anatomic pathology laboratory information system: analysis of benefitsRodney A Schmidt
Department of Pathology, University of Washington, Seattle, WA 98195 6100, USA
Am J Clin Pathol 126:678-83. 2006..This simple, integrated SDMS is an excellent value in a practice like ours, and many of the benefits likely apply in other practice settings...
- Cut-resistant protective gloves in pathology--effective and cost-effectiveFlorian R Fritzsche
Institute of Pathology, Charite Universitatsmedizin Berlin, Campus Mitte Charitéplatz 1, 10117 Berlin, Germany
Virchows Arch 452:313-8. 2008..We strongly recommend the use of such gloves, especially for autopsy personnel...
- Acquisition and use of digital images for pathology education and practiceKristina T C Panizzi
University of Alabama, Birmingham AL, USA
Adv Exp Med Biol 563:178-93. 2005
- Molecular pathology in the preclinical development of biopharmaceuticalsN A Gillett
Sierra Biomedical, Inc, Sparks, Nevada 89431, USA
Toxicol Pathol 27:48-52. 1999..e., the slide). In this manuscript, we briefly discussed the use and impact of these slide-based techniques within all phases of drug development in the pharmaceutical industry...
- [Recent advance in diagnostic telepathology]Xin xia Li
Zhonghua Bing Li Xue Za Zhi 35:176-8. 2006
- Pathology practice and pharmacogenomicsRonald Ja Trent
Sydney Medical School, University of Sydney, NSW, Australia
Pharmacogenomics 11:105-11. 2010..These two prerequisites are now being sought through the concept of 'personalized medicine'. Much has been occurring in a relatively short time frame, and as a consequence, education becomes a major rate-limiting step to change...
- From telepathology to virtual pathology institution: the new world of digital pathologyK Kayser
UICC TPCC, Institute of Pathology, Charite, Berlin, Germany
Rom J Morphol Embryol 45:3-9. 1999..Industrial and scientific efforts will probably allow an implementation of this technique within the next two years with exciting diagnostic and scientific perspectives...
- How informative are dermatopathology requisition forms completed by dermatologists? A review of the clinical information provided for 100 consecutive melanocytic lesionsJeanette M Waller
Department of Dermatology, University of California, San Francisco, California 94115, USA
J Am Acad Dermatol 62:257-61. 2010..Accurate clinicopathologic correlation can be crucial to arriving at the correct microscopic diagnosis...
- Developing and fostering a dynamic program for training in veterinary pathology and clinical pathology: veterinary students to post-graduate educationMichael D Lairmore
Department of Veterinary Bioscience, The Ohio State University, Columbus, OH 43210 1093, USA
J Vet Med Educ 34:464-72. 2007....
- [The 2005 Nobel Prize in Medicine: after stress, bacterial infection]Philippe Jeanteur
Bull Cancer 92:929. 2005
- Veterinary clinical pathologists in the biopharmaceutical industryA Eric Schultze
Department of Pathology, Lilly Research Laboratories, A Division of Eli Lilly and Company, Greenfield, IN, USA
Vet Clin Pathol 37:146-58. 2008..Current trainees in veterinary clinical pathology may choose to pursue careers in academe, diagnostic laboratories, government health services, ..
- Infectious diseases and pathology: opportunities and challengesMichael L Wilson
Am J Clin Pathol 125:654-5. 2006
- Pathology graduate medical education (overview from 1926 to 2005)C Bruce Alexander
Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
Hum Pathol 37:923-8. 2006..Factors shaping pathology residency training are reviewed, as well as future trends that will impact training curricula...
- Antibody expiration in the context of resource limitation: what is the evidence basis?Erica C Savage
Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, USA
Am J Clin Pathol 134:60-4. 2010..Negligible differences exist in immunostaining between outdated and current antibodies. Thus, exemption for primary antibodies from existing regulations would conserve resources without adversely impacting patient care...
- INTEGRATION OF FIBROBLAST FUNCTIONING IN WOUND HEALINGAlan Wells; Fiscal Year: 2003..Understanding the delicate balance of these molecular mechanisms is important for rationally designing interventions to achieve normal wound healing. ..
- Dermal-Epidermal Communication during Wound HealingAlan Wells; Fiscal Year: 2008..These investigations will define key extracellular and intracellular molecules for wound resolution. These are potential targets for rationally designed interventions to promote normal wound healing and limit scarring. ..
- ASPL TFE3 fusion in human cancersMarc Ladanyi; Fiscal Year: 2006..3->qter; and finally analyze selected candidate genes in the same region for inactivating mutations. ..
- Alpha2Beta1 Integrin and Cell Surface MMP-1 ActivitySamuel Santoro; Fiscal Year: 2006..abstract_text> ..
- Improving Patient Safety by Examining Pathology ErrorsStephen Raab; Fiscal Year: 2006..abstract_text> ..
- MEASLES VIRUS STUDIES IN A TRANSGENIC MODELMichael Oldstone; Fiscal Year: 2007..abstract_text> ..
- Mesothelioma Virtual Bank for Translational ResearchMichael Becich; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- ER Reporter Genes To Predict Response To Endocrine TherapyWILLIAM SYMMANS; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Therapeutics to Prevent/Treat Lassa Fever VirusMichael B Oldstone; Fiscal Year: 2010..We anticipate making a significant contribution to drug development to treat these BSL-4 agents. ..
- A Community-shared Clinical Abstract to Improve CareDONALD CONNELLY; Fiscal Year: 2007..abstract_text> ..
- MOLECULAR MODELING OF DIAGNOSIS AND PROGNOSIS IN HNSCCMaria Worsham; Fiscal Year: 2009..abstract_text> ..
- Aging Disease--Prion/Transgenic/Immunologic StudiesMichael Oldstone; Fiscal Year: 2008..Lastly, Jose Criado will continue his electrophysiology and behavioral studies on the normal function of PrP and on its aberrations during TSE disease. ..
- CHEMOKINE RECEPTOR DYNAMICS IN GRANULOMA FORMATIONStephen Chensue; Fiscal Year: 2008..The studies proposed herein will help the design of improved approaches to vaccine development and therapies to control chronic destructive inflammatory responses. ..
- Competencies Training &Assessment in LaboratoryMedicine UsingPatientSimulationsFred R Dee; Fiscal Year: 2010..research will be carried out in medical school courses at the University of Iowa an in laboratory medicine (clinical pathology) residency training programs at the University of Iowa Hospitals and Clinics and elsewhere...
- Retrieval of DNA, RNA, and Protein from Archival TissueClive Taylor; Fiscal Year: 2005..the National Institute of Standards and Technology (NIST), and the University of California, San Francisco. ..
- Role of Gene Amplification in Breast CancerJonathan Pollack; Fiscal Year: 2007..abstract_text> ..
- RESEARCH TRAINING IN TRANSFUSION MEDICINEJeffrey McCullough; Fiscal Year: 2003..abstract_text> ..
- VIRUSES AND AUTOIMMUNE DISEASEMichael Oldstone; Fiscal Year: 2001..The second order of business is to determine the role of "self" (islet-cell) antigens other than the initial triggering viral antigen in the pathogenetic process leading to and determine their role in IDDM. ..
- MAP KINASE SIGNALING IN ASTROGLIAL REACTIONSJames Mandell; Fiscal Year: 2003..3) To generate transgenic mice expressing astrocyte-targeted activators of the ERK/MAPK pathway as critical tests of the working hypothesis. ..
- REVERSIBLE PATHOLOGY OF THE PLATELET STORAGE LESIONBrian Smith; Fiscal Year: 2001..The long term goal of the project, which combines the synergistic expertise of several established investigators, is to improve the clinical results of platelet transfusion. ..
- Retrieval of DNA, RNA and Protein from Archival TissuesClive Taylor; Fiscal Year: 2002..This is followed by secondary condensation reaction for both proteins and nucleic acids, resulting in the formation of a stable methylene compound. ..
- BENIGN BREAST DISEASE--MOLECULAR DIFFERENTIATION OF RISKMaria Worsham; Fiscal Year: 2001....
- ANIMAL MODELS OF MOLECULAR PATHOGENSIS OF HTLV-1Michael Lairmore; Fiscal Year: 2003..Collectively, our research groups provide a coordinated approach to develop state-of-the-art animal models to further knowledge of the events of HTLV-1 pathogenesis. ..
- FEASIBILITY OF PRENATAL SCREENING FOR SLO SYNDROMEGeorge Knight; Fiscal Year: 2003..The study will also aid in refining prevalence estimates by race and ethnicity, and will determine whether several rare disorders in the cholesterol biosynthetic pathway would be detectable. ..
- Prenatal Risk Factors for Neuropsychiatric DiseaseCarolyn Salafia; Fiscal Year: 2007..My training objectives are directly related to my proposed research, which focuses on the evaluation of the intrauterine environment and how predispositions to ND/NP compromise arise in utero. ..
- AMYLOIDOGENIC EFFECTS OF CHOLINERGIC DENERVATIONThomas Beach; Fiscal Year: 2002..This could lead to impaired cerebral vasoregulation and increased susceptibility to ischemia, further compromising cortical function in AD. ..
- A SHARED TISSUE RESOURCE FOR THE MOLECULAR CLASSIFACTIONMichael Becich; Fiscal Year: 2005..The purpose of this proposal is to provide prostate cancer researchers with a next-generation tissue banking resources to catalyze research innovations in prostate cancer biology, detection and treatment. ..
- Viruses and DiabetesMichael Oldstone; Fiscal Year: 2005....
- Arenavirus Receptor-Structure/Function StudiesMichael B Oldstone; Fiscal Year: 2010..These findings have relevance for biodefense of several viruses including LFV. ..
- Gene Amplification and Deletion in Pancreatic CancerJonathan R Pollack; Fiscal Year: 2010..abstract_text> ..
- Pathogenetics of a Clinically-favorable Prostate Cancer SubtypeJonathan R Pollack; Fiscal Year: 2010..Our findings may also suggest novel gene-based markers for the diagnosis of clinically- favorable tumors, leading to improved treatment stratification and clinical management of men with prostate cancer. ..
- Functions of ERK and p38 MAP Kinases in AstrogliosisJames Mandell; Fiscal Year: 2008..This approach could promote recovery of brain and spinal cord function after injury or stroke. [unreadable] [unreadable]..
- Interferon gamma in autoimmune thyroiditis & thyroid functionPatrizio Caturegli; Fiscal Year: 2007..We also hypothesize that augmented TSH signaling is required to induce the adipocyte-rich phenotype, and cross thyr-IFNg transgenics to TSH receptor knockout mice. ..
- Hypoglycemic signaling targets in astrocytesJames Mandell; Fiscal Year: 2003..The longterm goal is to develop pharmacologic or molecular methods to augment or modulate neuroprotective aspects of the astrocytic response to hypoglycemia. ..
- Prostate Cancer Harbinger GenesMark Rubin; Fiscal Year: 2006..abstract_text> ..
- RESEARCH TRAINING FOR VETERINARY STUDENTSMichael Lairmore; Fiscal Year: 2005....
- Pathogenesis Studies in Scrapie (TSE Diseases)Michael Oldstone; Fiscal Year: 2003..This model should be useful to study pathophysiology of CWD as well as probing CWD strain differences. ..
- VIRTUAL SLIDEBOX OF COMPARATIVE CANCER PATHOLOGYFred Dee; Fiscal Year: 2005..abstract_text> ..
- Mechanism of p12I and p30II in HTLV1 InfectionMichael Lairmore; Fiscal Year: 2003..Our long-term goal is to understand the role of p12-I and p30-II in the establishment of HTLV-1 infection in vivo. ..
- STUDIES OF A NEW MYELIN GENE THAT CAUSES CNS DISEASEMichael Oldstone; Fiscal Year: 2001..Their studies in rodents combined with those of their collaborator, Dr. Martin, should begin to characterize the role played by MONP in neurologic disease. ..
- Platelet-Leukocyte Physiology in Cardiopulmonary BypassBrian Smith; Fiscal Year: 2005..induced by SECC; (3) examine the effects of SECC on human endothelial cells by in vitro modeling, specifically including alterations in tissue factor regulation and the effect of differential complement components ..
- VASCULAR CELL COLLAGEN RECEPTORSSamuel Santoro; Fiscal Year: 2002..abstract_text> ..