Omeprazole treatment of children with peptic esophagitis refractory to ranitidine therapy
Over 150 children prospectively underwent upper endoscopy for complaints of epigastric pain revealing oesophagitis in 84%. They were then treated with ranitidine. Seventy per cent responded to the ranitidine with the remainder progressing onto omeprazole, when 87% responded. The conclusion is that oesophagitis is fairly common in children, especially when there are specific symptoms, and usually is very responsive to therapy.