I would say that, if you are going to use chapter titles, you really need to have a very clear understanding of what you're doing and how your readers might react to them. So, rather than doing chapter titles because you think it would be fun, have a very specific and well thought out reason for them.
One example that comes to mind is George R. R. Martin's Game of Thrones. Rather than using traditional chapter numbers or titles, he labelled each new chapter with the name of the point-of-view character for that chapter. Given how many POV characters there are, this immediately lets you know who each chapter is about without even having to read one line of the chapter itself. So, it's less confusing overall.