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Biosensors present exciting opportunities in novel medical and scientific applications. However, sensor tags presented to date cannot interface with practical sensors, lack addressability, and/or require a custom (high-cost) interrogator. Our tag provides these features via ultra-low-power circuitry including a low-noise biosignal amplifier, unique tag ID generator, calibration-free 3 MHz oscillator, and EPC C1 Gen2 protocol compatibility. In addition to design details and measurement data from the fabricated IC, we present in vivo muscle temperature measurement from an untethered in-flight hawkmoth.