Affiliation: University of Massachusetts Medical Center
- Are there multiple pathways in the pathogenesis of Huntington's disease?N Aronin
Department of Medicine, University of Massachusetts Medical School, Worcester 01655, USA
Philos Trans R Soc Lond B Biol Sci 354:995-1003. 1999..We propose that mutant huntingtin engages multiple pathogenic pathways leading to neuronal death...
- N-methyl-D-aspartate receptor activation in the neostriatum increases c-fos and fos-related antigens selectively in medium-sized neuronsN Aronin
Department of Medicine, University of Massachusetts Medical School, Worcester 01655
Neuroscience 44:409-20. 1991....
- Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's diseaseG A Laforet
Departments of Psychiatry and Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
J Neurosci 21:9112-23. 2001..Results suggest that motor deficits in Huntington's disease arise from cumulative morphological and physiological changes in neurons that impair corticostriatal circuitry...