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FTLD_203830616_02613_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177715_dupl_3
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal on the right), posterior insula (mild atrophy on the left and normal on the right) and central operculum (mild atrophy on the left)
- no appreciable degenerative or atrophic changes observed in the frontal lobe
- parietal lobe maintains a normal appearance with no observable atrophic features
- no findings suggestive of atrophy are seen in the occipital lobe
- moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right), sup. temporal gyrus (mild atrophy on the left), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and planum polare (mild atrophy on the left and normal on the right)
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (moderate atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (mild atrophy both left and right)
For the subcortical structures:
- the thalamus shows no notable changes suggestive of atrophy
- severe atrophy of the left amygdala and moderate atrophy of the right amygdala
- mild bilateral atrophy of the caudate
- mild atrophy of the left accumbens; the right accumbens is normal
- the pallidum shows no notable changes suggestive of atrophy
- mild atrophy of the left putamen; the right putamen is normal
- mild-to-moderate atrophy of the left hippocampus, mild atrophy of the right hippocampus
For the ventricles:
- 3rd ventricle maintains its expected proportions without signs of enlargement
- severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
- no findings suggestive of enlargement are seen in the external csf
- the 4th ventricle shows no notable changes suggestive of enlargement
- mild enlargement of the left lateral ventricle; the right lateral ventricle is normal
For additional Regions of Interest:
- no findings suggestive of atrophy are seen in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- no clear atrophic alterations are visible in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- moderate-to-severe atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) and mild atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) maintains a normal appearance with no observable atrophic features
|
SV
|
FTLD_203307240_03040_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177390_dupl_2
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal-to-mild atrophy on the right) and parahippocampal gyrus (mild atrophy on the left and normal on the right)
- no observable atrophic changes in the frontal lobe
- parietal lobe appears within normal limits without apparent atrophy
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal on the right) and posterior insula (mild atrophy on the left and normal on the right)
- severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left), planum polare (mild-to-moderate atrophy on the left and normal on the right), sup. temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), transverse temporal gyrus (mild atrophy on the left and normal on the right), planum temporale (mild atrophy on the right) and middle temporal gyrus (mild atrophy on the left)
- the occipital lobe shows no notable changes suggestive of atrophy
For the subcortical structures:
- mild atrophy of the left caudate; the right caudate is normal
- accumbens appears preserved, with no observable tissue loss
- mild atrophy of the left pallidum; the right pallidum is normal
- no evident atrophy or tissue thinning seen in the thalamus
- mild atrophy of the left putamen; the right putamen is normal
- moderate bilateral atrophy of the amygdala
- mild-to-moderate atrophy of the left hippocampus
For the ventricles:
- moderate enlargement of the left lateral ventricle; the right lateral ventricle is normal
- severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- no observable enlargement of the external csf
- 3rd ventricle appears within normal size limits with no apparent enlargement
- the 4th ventricle shows no notable changes suggestive of enlargement
For additional Regions of Interest:
- no clear atrophic alterations are visible in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- no appreciable degenerative or atrophic changes observed in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- severe atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) and mild atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) shows no notable changes suggestive of atrophy
|
SV
|
FTLD_203189340_02048_MR_Sagittal_MP-Rage_br_raw_20230209094701503_I10183270_dupl_4
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the insular cortex shows no notable changes suggestive of atrophy
- limbic cortex appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the occipital lobe
- no evident atrophy or tissue thinning seen in the temporal lobe
- no appreciable degenerative or atrophic changes observed in the frontal lobe
- parietal lobe demonstrates a healthy morphology without signs of atrophy
For the subcortical structures:
- putamen appears within normal limits without apparent atrophy
- no appreciable degenerative or atrophic changes observed in the accumbens
- no evident atrophy or tissue thinning seen in the hippocampus
- amygdala appears preserved, with no observable tissue loss
- thalamus demonstrates a healthy morphology without signs of atrophy
- pallidum appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the caudate
For the ventricles:
- 3rd ventricle appears within normal size limits with no apparent enlargement
- mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- no findings suggestive of enlargement are seen in the lateral ventricle
- no clear enlargement or abnormal growth seen in the external csf
- 4th ventricle maintains its expected proportions without signs of enlargement
For additional Regions of Interest:
- no findings suggestive of atrophy are seen in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- no evident atrophy or tissue thinning seen in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- no findings suggestive of atrophy are seen in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
BV
|
FTLD_203149534_01434_MR_Sagittal_MP-Rage_br_raw_20230206142016642_I10181173_dupl_10
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no appreciable enlargement noted in the 4th ventricle
- moderate enlargement of the 3rd ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- no clear enlargement or abnormal growth seen in the external csf
- severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
For the cerebral cortex:
- temporal lobe demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: central operculum (mild-to-moderate atrophy on the left and normal on the right) and parietal operculum (mild atrophy on the left and normal on the right)
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- mild-to-moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: anterior orbital gyrus (mild atrophy both left and right), precentral gyrus (mild atrophy both left and right), precentral gyrus medial segment (mild atrophy both left and right), opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), middle frontal gyrus (mild atrophy on the left and normal on the right), posterior orbital gyrus (mild atrophy on the left and normal on the right), sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the left), medial frontal cortex (mild atrophy on the left) and lateral orbital gyrus (mild atrophy on the left)
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: posterior cingulate gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right)
- no appreciable degenerative or atrophic changes observed in the parietal lobe
For the subcortical structures:
- thalamus appears preserved, with no observable tissue loss
- mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen
- mild bilateral atrophy of the accumbens
- amygdala appears within normal limits without apparent atrophy
- mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate
- hippocampus appears within normal limits without apparent atrophy
- no observable atrophic changes in the pallidum
For additional Regions of Interest:
- mild bilateral atrophy of the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild-to-moderate atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) appears within normal limits without apparent atrophy
- no observable atrophic changes in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
PNFA
|
FTLD_203117063_03361_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176826_dupl_3
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild-to-moderate atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left), anterior cingulate gyrus (mild atrophy both left and right) and middle cingulate gyrus (normal on the left and mild atrophy on the right)
- moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal-to-mild atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right), frontal operculum (mild atrophy both left and right), central operculum (mild-to-moderate atrophy on the left) and parietal operculum (mild atrophy on the left and normal on the right)
- the parietal lobe shows no notable changes suggestive of atrophy
- severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: sup. temporal gyrus (moderate atrophy on the left and mild atrophy on the right), planum temporale (mild atrophy both left and right), middle temporal gyrus (moderate atrophy on the left and normal on the right), temporal pole (moderate atrophy on the left and normal on the right), fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), planum polare (mild atrophy on the left and normal on the right) and transverse temporal gyrus (mild atrophy on the left and normal on the right)
- no evident atrophy or tissue thinning seen in the occipital lobe
- mild-to-moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild atrophy both left and right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (mild atrophy on the left), gyrus rectus (normal on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy on the left and normal on the right), frontal pole (mild atrophy on the left), anterior orbital gyrus (mild atrophy on the left) and sup. frontal gyrus medial segment (mild atrophy on the left)
For the ventricles:
- severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- moderate enlargement of the 3rd ventricle
- the 4th ventricle shows no notable changes suggestive of enlargement
- moderate enlargement of the external csf
- moderate-to-severe enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle
For the subcortical structures:
- severe atrophy of the left hippocampus, moderate atrophy of the right hippocampus
- moderate atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- moderate atrophy of the left amygdala and mild atrophy of the right amygdala
- moderate-to-severe atrophy of the left thalamus; the right thalamus is normal
- moderate atrophy of the left caudate; normal-to-mild atrophy of the right caudate
- moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens
- moderate-to-severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
For additional Regions of Interest:
- mild atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) is normal
- mild-to-moderate atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); normal-to-mild atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- severe atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala); the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) is normal
- moderate atrophy of the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus); the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) is normal
|
SV
|
ADNI_114_S_0166_MR_MT1__GradWarp__N3m_Br_20130313091841852_S183237_I362898_dupl_1
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild bilateral atrophy of the accumbens
- severe atrophy of the left amygdala and moderate atrophy of the right amygdala
- no findings suggestive of atrophy are seen in the thalamus
- no appreciable degenerative or atrophic changes observed in the pallidum
- no appreciable degenerative or atrophic changes observed in the caudate
- moderate atrophy of the left hippocampus, moderate atrophy of the right hippocampus
- no evident atrophy or tissue thinning seen in the putamen
For the ventricles:
- severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- the external csf shows no notable changes suggestive of enlargement
- moderate enlargement of the 4th ventricle
- mild enlargement of the 3rd ventricle
For the cerebral cortex:
- occipital lobe maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the parietal lobe
- limbic cortex demonstrates a healthy morphology without signs of atrophy
- frontal lobe appears preserved, with no observable tissue loss
- insular cortex appears preserved, with no observable tissue loss
- mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (mild atrophy on the left), planum polare (mild atrophy on the right) and temporal pole (mild atrophy on the left)
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) maintains a normal appearance with no observable atrophic features
- no findings suggestive of atrophy are seen in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- mild-to-moderate atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala); the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) is normal
- mild bilateral atrophy of the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
AD
|
FTLD_203687992_01298_MR_Sagittal_MP-Rage_br_raw_20230124213456308_I10178692
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the limbic cortex shows no notable changes suggestive of atrophy
- no evident atrophy or tissue thinning seen in the occipital lobe
- the frontal lobe shows no notable changes suggestive of atrophy
- the parietal lobe shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the temporal lobe
- mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (mild atrophy both left and right) and frontal operculum (normal-to-mild atrophy on the left and mild atrophy on the right)
For the ventricles:
- no evident size increase noted in the external csf
- inf. lateral ventricle maintains its expected proportions without signs of enlargement
- no evident size increase noted in the 3rd ventricle
- lateral ventricle appears within normal size limits with no apparent enlargement
- no evident size increase noted in the 4th ventricle
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the caudate
- no clear atrophic alterations are visible in the pallidum
- no evident atrophy or tissue thinning seen in the accumbens
- thalamus appears within normal limits without apparent atrophy
- the putamen shows no notable changes suggestive of atrophy
- mild atrophy of the left amygdala; the right amygdala is normal
- hippocampus appears within normal limits without apparent atrophy
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) appears preserved, with no observable tissue loss
- no findings suggestive of atrophy are seen in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) maintains a normal appearance with no observable atrophic features
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) maintains a normal appearance with no observable atrophic features
|
CN
|
FTLD_203163034_02436_MR_Sagittal_MP-Rage_br_raw_20230209101942649_I10183429_dupl_10
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no observable atrophic changes in the parietal lobe
- no findings suggestive of atrophy are seen in the limbic cortex
- temporal lobe appears within normal limits without apparent atrophy
- mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild atrophy both left and right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (mild-to-moderate atrophy on the left and normal on the right) and gyrus rectus (mild atrophy on the left and normal on the right)
- no observable atrophic changes in the occipital lobe
- insular cortex appears within normal limits without apparent atrophy
For the ventricles:
- no findings suggestive of enlargement are seen in the inf. lateral ventricle
- the 4th ventricle shows no notable changes suggestive of enlargement
- mild-to-moderate enlargement of the external csf
- mild enlargement of the 3rd ventricle
- no appreciable enlargement noted in the lateral ventricle
For the subcortical structures:
- mild atrophy of the left amygdala; the right amygdala is normal
- mild atrophy of the left putamen; the right putamen is normal
- mild bilateral atrophy of the pallidum
- mild-to-moderate atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens
- mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate
- no clear atrophic alterations are visible in the hippocampus
- thalamus appears preserved, with no observable tissue loss
For additional Regions of Interest:
- mild-to-moderate atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) and mild atrophy of the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- mild atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala); the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) is normal
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) demonstrates a healthy morphology without signs of atrophy
|
PNFA
|
ADNI_005_S_10300_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20250106184753237_1_I11088080
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no clear enlargement or abnormal growth seen in the lateral ventricle
- no clear enlargement or abnormal growth seen in the external csf
- mild-to-moderate enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle
- 4th ventricle maintains its expected proportions without signs of enlargement
- 3rd ventricle maintains a typical volume without observable enlargement
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the putamen
- no observable atrophic changes in the accumbens
- the amygdala shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the thalamus
- pallidum appears preserved, with no observable tissue loss
- the caudate shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the hippocampus
For the cerebral cortex:
- no observable atrophic changes in the limbic cortex
- insular cortex maintains a normal appearance with no observable atrophic features
- no evident atrophy or tissue thinning seen in the frontal lobe
- no clear atrophic alterations are visible in the parietal lobe
- no findings suggestive of atrophy are seen in the temporal lobe
- the occipital lobe shows no notable changes suggestive of atrophy
For additional Regions of Interest:
- no findings suggestive of atrophy are seen in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- no observable atrophic changes in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) maintains a normal appearance with no observable atrophic features
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
CN
|
ADNI_012_S_5213_MR_MPRAGE_SENSE2__br_raw_20130722150031094_1_S196004_I381908
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no evident atrophy or tissue thinning seen in the frontal lobe
- insular cortex appears within normal limits without apparent atrophy
- no clear atrophic alterations are visible in the limbic cortex
- no appreciable degenerative or atrophic changes observed in the temporal lobe
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- parietal lobe maintains a normal appearance with no observable atrophic features
For the ventricles:
- no observable enlargement of the external csf
- 3rd ventricle maintains its expected proportions without signs of enlargement
- no clear enlargement or abnormal growth seen in the 4th ventricle
- no observable enlargement of the lateral ventricle
- no evident size increase noted in the inf. lateral ventricle
For the subcortical structures:
- hippocampus maintains a normal appearance with no observable atrophic features
- no appreciable degenerative or atrophic changes observed in the caudate
- pallidum appears preserved, with no observable tissue loss
- no observable atrophic changes in the thalamus
- no appreciable degenerative or atrophic changes observed in the putamen
- no evident atrophy or tissue thinning seen in the amygdala
- no findings suggestive of atrophy are seen in the accumbens
For additional Regions of Interest:
- no findings suggestive of atrophy are seen in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- no findings suggestive of atrophy are seen in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) demonstrates a healthy morphology without signs of atrophy
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) appears within normal limits without apparent atrophy
|
CN
|
FTLD_203651746_02645_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178160_dupl_10
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- insular cortex maintains a normal appearance with no observable atrophic features
- occipital lobe appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal on the left and mild atrophy on the right)
- no findings suggestive of atrophy are seen in the parietal lobe
- temporal lobe appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the frontal lobe
For the ventricles:
- moderate bilateral enlargement of the inf. lateral ventricle
- 3rd ventricle maintains its expected proportions without signs of enlargement
- mild enlargement of the 4th ventricle
- no appreciable enlargement noted in the external csf
- moderate enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
For the subcortical structures:
- mild atrophy of the left hippocampus, mild atrophy of the right hippocampus
- mild bilateral atrophy of the accumbens
- mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum
- moderate atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
- thalamus appears within normal limits without apparent atrophy
- mild atrophy of the right amygdala; the left amygdala is normal
- mild atrophy of the left caudate; the right caudate is normal
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) appears preserved, with no observable tissue loss
- mild atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- no observable atrophic changes in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) maintains a normal appearance with no observable atrophic features
|
PNFA
|
ADNI_070_S_4719_MR_MPRAGE_br_raw_20120521142246850_171_S151143_I305573_dupl_1
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- pallidum appears within normal limits without apparent atrophy
- no observable atrophic changes in the accumbens
- no appreciable degenerative or atrophic changes observed in the thalamus
- putamen demonstrates a healthy morphology without signs of atrophy
- moderate atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala
- no findings suggestive of atrophy are seen in the caudate
- moderate atrophy of the left hippocampus, early/mild-grade volumetric reduction of the right hippocampus
For the ventricles:
- external csf appears to be of normal dimensions, with no observable increase in size
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
- no observable enlargement of the 3rd ventricle
- mild-to-moderate enlargement of the left lateral ventricle; the right lateral ventricle is normal
- moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
For the cerebral cortex:
- moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right), sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and temporal pole (mild-to-moderate atrophy on the left and normal on the right)
- mild atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), precuneus (mild-to-moderate atrophy on the left and normal on the right) and sup. parietal lobule (normal-to-mild atrophy on the left and mild atrophy on the right)
- mild atrophy of the left insular cortex; the right insular cortex is normal
- mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right) and posterior cingulate gyrus (mild atrophy both left and right)
- no clear atrophic alterations are visible in the occipital lobe
- frontal lobe appears within normal limits without apparent atrophy
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- moderate atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) and mild atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild-to-moderate atrophy of the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) and mild atrophy of the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
AD
|
ADNI_941_S_6574_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180910150437316_132_S725816_I1046901
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no findings suggestive of enlargement are seen in the 3rd ventricle
- the external csf shows no notable changes suggestive of enlargement
- 4th ventricle maintains its expected proportions without signs of enlargement
- no evident size increase noted in the lateral ventricle
- no clear enlargement or abnormal growth seen in the inf. lateral ventricle
For the cerebral cortex:
- the insular cortex shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the parietal lobe
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy on the left and normal on the right)
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- no appreciable degenerative or atrophic changes observed in the temporal lobe
- no observable atrophic changes in the frontal lobe
For the subcortical structures:
- mild atrophy of the right accumbens; the left accumbens is normal
- pallidum appears preserved, with no observable tissue loss
- thalamus maintains a normal appearance with no observable atrophic features
- no evident atrophy or tissue thinning seen in the hippocampus
- no observable atrophic changes in the amygdala
- the caudate shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the putamen
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) appears within normal limits without apparent atrophy
- no observable atrophic changes in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- no findings suggestive of atrophy are seen in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
CN
|
FTLD_203590286_02689_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176953_dupl_3
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no observable atrophic changes in the limbic cortex
- no observable atrophic changes in the frontal lobe
- no findings suggestive of atrophy are seen in the insular cortex
- mild bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy both left and right) and sup. temporal gyrus (mild atrophy on the left and normal on the right)
- occipital lobe appears preserved, with no observable tissue loss
- no clear atrophic alterations are visible in the parietal lobe
For the subcortical structures:
- hippocampus demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the left accumbens; the right accumbens is normal
- mild bilateral atrophy of the caudate
- no evident atrophy or tissue thinning seen in the putamen
- the pallidum shows no notable changes suggestive of atrophy
- no observable atrophic changes in the amygdala
- thalamus appears preserved, with no observable tissue loss
For the ventricles:
- 3rd ventricle appears within normal size limits with no apparent enlargement
- external csf appears to be of normal dimensions, with no observable increase in size
- inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size
- lateral ventricle maintains its expected proportions without signs of enlargement
- no findings suggestive of enlargement are seen in the 4th ventricle
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) maintains a normal appearance with no observable atrophic features
- mild atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- mild atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala); the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) is normal
- no evident atrophy or tissue thinning seen in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
PNFA
|
FTLD_203953797_02795_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176885_dupl_17
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- inf. lateral ventricle maintains a typical volume without observable enlargement
- mild-to-moderate enlargement of the 4th ventricle
- 3rd ventricle appears within normal size limits with no apparent enlargement
- mild enlargement of the left lateral ventricle; the right lateral ventricle is normal
- moderate enlargement of the external csf
For the cerebral cortex:
- mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: opercular inf. frontal gyrus (mild atrophy both left and right), gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle frontal gyrus (mild atrophy on the left and normal on the right)
- no clear atrophic alterations are visible in the occipital lobe
- the parietal lobe shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the temporal lobe
- limbic cortex demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the insular cortex
For the subcortical structures:
- hippocampus demonstrates a healthy morphology without signs of atrophy
- moderate-to-severe bilateral atrophy of the pallidum
- mild bilateral atrophy of the amygdala
- moderate atrophy of the left putamen and moderate-to-severe atrophy of the right putamen
- mild bilateral atrophy of the thalamus
- moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- severe bilateral atrophy of the caudate
For additional Regions of Interest:
- no findings suggestive of atrophy are seen in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) demonstrates a healthy morphology without signs of atrophy
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
PNFA
|
FTLD_203260125_02526_MR_Sagittal_MP-Rage_br_raw_20230206161248652_I10181566_dupl_13
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild bilateral atrophy of the accumbens
- no findings suggestive of atrophy are seen in the amygdala
- no findings suggestive of atrophy are seen in the hippocampus
- mild bilateral atrophy of the thalamus
- putamen maintains a normal appearance with no observable atrophic features
- mild atrophy of the left caudate and mild-to-moderate atrophy of the right caudate
- no evident atrophy or tissue thinning seen in the pallidum
For the cerebral cortex:
- limbic cortex appears within normal limits without apparent atrophy
- parietal lobe appears within normal limits without apparent atrophy
- mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: frontal operculum (mild atrophy both left and right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and central operculum (normal on the left and mild atrophy on the right)
- moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (mild-to-moderate atrophy both left and right), precentral gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), precentral gyrus medial segment (mild atrophy on the left and mild-to-moderate atrophy on the right), supplementary motor cortex (mild atrophy both left and right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right), lateral orbital gyrus (mild atrophy on the left and normal on the right), sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right), frontal pole (normal on the left and mild atrophy on the right) and medial frontal cortex (mild atrophy on the left)
- mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy both left and right), transverse temporal gyrus (mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right)
- the occipital lobe shows no notable changes suggestive of atrophy
For the ventricles:
- mild-to-moderate enlargement of the external csf
- mild-to-moderate enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- mild enlargement of the 4th ventricle
- moderate-to-severe enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle
- moderate-to-severe enlargement of the 3rd ventricle
For additional Regions of Interest:
- mild-to-moderate atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) and moderate atrophy of the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
PNFA
|
ADNI_114_S_4404_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180103125130893_36_S647359_I949873_dupl_1
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no findings suggestive of atrophy are seen in the caudate
- the pallidum shows no notable changes suggestive of atrophy
- mild atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala
- early/mild-grade volumetric reduction of the left hippocampus
- the accumbens shows no notable changes suggestive of atrophy
- the thalamus shows no notable changes suggestive of atrophy
- no observable atrophic changes in the putamen
For the ventricles:
- mild-to-moderate enlargement of the 3rd ventricle
- no clear enlargement or abnormal growth seen in the external csf
- no appreciable enlargement noted in the 4th ventricle
- mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle
- mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the insular cortex
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left and right)
- no findings suggestive of atrophy are seen in the temporal lobe
- parietal lobe appears preserved, with no observable tissue loss
- frontal lobe appears preserved, with no observable tissue loss
- no observable atrophic changes in the occipital lobe
For additional Regions of Interest:
- no appreciable degenerative or atrophic changes observed in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) appears within normal limits without apparent atrophy
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
AD
|
FTLD_203651746_02645_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178160_dupl_14
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild enlargement of the 4th ventricle
- moderate bilateral enlargement of the inf. lateral ventricle
- 3rd ventricle appears within normal size limits with no apparent enlargement
- external csf appears within normal size limits with no apparent enlargement
- moderate enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
For the subcortical structures:
- mild bilateral atrophy of the accumbens
- no evident atrophy or tissue thinning seen in the thalamus
- mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum
- mild atrophy of the left hippocampus, mild atrophy of the right hippocampus
- mild atrophy of the left caudate; the right caudate is normal
- moderate atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
- mild atrophy of the right amygdala; the left amygdala is normal
For the cerebral cortex:
- occipital lobe maintains a normal appearance with no observable atrophic features
- the frontal lobe shows no notable changes suggestive of atrophy
- no evident atrophy or tissue thinning seen in the temporal lobe
- no clear atrophic alterations are visible in the limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal on the left and mild atrophy on the right)
- no findings suggestive of atrophy are seen in the parietal lobe
- no evident atrophy or tissue thinning seen in the insular cortex
For additional Regions of Interest:
- no clear atrophic alterations are visible in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) shows no notable changes suggestive of atrophy
- no evident atrophy or tissue thinning seen in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
PNFA
|
FTLD_203681662_03268_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450435_dupl_3
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no evident atrophy or tissue thinning seen in the parietal lobe
- limbic cortex maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the frontal lobe
- no appreciable degenerative or atrophic changes observed in the insular cortex
- occipital lobe appears within normal limits without apparent atrophy
- temporal lobe appears preserved, with no observable tissue loss
For the subcortical structures:
- accumbens appears preserved, with no observable tissue loss
- pallidum maintains a normal appearance with no observable atrophic features
- thalamus maintains a normal appearance with no observable atrophic features
- the amygdala shows no notable changes suggestive of atrophy
- putamen maintains a normal appearance with no observable atrophic features
- caudate maintains a normal appearance with no observable atrophic features
- hippocampus maintains a normal appearance with no observable atrophic features
For the ventricles:
- the lateral ventricle shows no notable changes suggestive of enlargement
- the 4th ventricle shows no notable changes suggestive of enlargement
- no appreciable enlargement noted in the inf. lateral ventricle
- 3rd ventricle maintains its expected proportions without signs of enlargement
- mild-to-moderate enlargement of the external csf
For additional Regions of Interest:
- mild atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) is normal
- salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) demonstrates a healthy morphology without signs of atrophy
|
PNFA
|
FTLD_203158026_03625_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047629_dupl_5
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no observable atrophic changes in the caudate
- the hippocampus shows no notable changes suggestive of atrophy
- mild atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- no observable atrophic changes in the amygdala
- mild atrophy of the left putamen; the right putamen is normal
- mild bilateral atrophy of the pallidum
- no findings suggestive of atrophy are seen in the thalamus
For the ventricles:
- no appreciable enlargement noted in the 4th ventricle
- no findings suggestive of enlargement are seen in the lateral ventricle
- mild enlargement of the 3rd ventricle
- external csf maintains its expected proportions without signs of enlargement
- no observable enlargement of the inf. lateral ventricle
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the insular cortex
- no findings suggestive of atrophy are seen in the occipital lobe
- the temporal lobe shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the frontal lobe
- no evident atrophy or tissue thinning seen in the parietal lobe
- no observable atrophic changes in the limbic cortex
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) maintains a normal appearance with no observable atrophic features
- the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) shows no notable changes suggestive of atrophy
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) demonstrates a healthy morphology without signs of atrophy
- no clear atrophic alterations are visible in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
PNFA
|
ADNI_073_S_0386_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070419144406195_S13746_I49680
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no findings suggestive of atrophy are seen in the caudate
- thalamus appears preserved, with no observable tissue loss
- no observable atrophic changes in the putamen
- accumbens appears preserved, with no observable tissue loss
- pallidum demonstrates a healthy morphology without signs of atrophy
- amygdala appears within normal limits without apparent atrophy
- hippocampus demonstrates a healthy morphology without signs of atrophy
For the ventricles:
- 4th ventricle appears within normal size limits with no apparent enlargement
- no findings suggestive of enlargement are seen in the 3rd ventricle
- lateral ventricle maintains a typical volume without observable enlargement
- no appreciable enlargement noted in the external csf
- no appreciable enlargement noted in the inf. lateral ventricle
For the cerebral cortex:
- temporal lobe appears within normal limits without apparent atrophy
- mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal on the right) and middle cingulate gyrus (normal on the left and mild atrophy on the right)
- the parietal lobe shows no notable changes suggestive of atrophy
- the frontal lobe shows no notable changes suggestive of atrophy
- the insular cortex shows no notable changes suggestive of atrophy
- no observable atrophic changes in the occipital lobe
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) demonstrates a healthy morphology without signs of atrophy
- no clear atrophic alterations are visible in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
CN
|
FTLD_203815518_03811_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451161_dupl_6
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- parietal lobe maintains a normal appearance with no observable atrophic features
- moderate-to-severe atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal on the right) and planum polare (mild-to-moderate atrophy on the left and normal on the right)
- moderate atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right), anterior insula (moderate atrophy on the left and normal-to-mild atrophy on the right) and central operculum (mild-to-moderate atrophy on the left and normal on the right)
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (mild atrophy both left and right), lateral orbital gyrus (mild atrophy on the left), medial frontal cortex (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal on the right), frontal pole (mild atrophy on the left and normal on the right), subcallosal area (mild atrophy on the left and normal on the right), medial orbital gyrus (mild atrophy on the left) and precentral gyrus (mild atrophy on the left)
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (mild-to-moderate atrophy on the left), entorhinal area (mild atrophy on the left and normal on the right) and middle cingulate gyrus (mild atrophy on the left and normal on the right)
For the ventricles:
- lateral ventricle appears to be of normal dimensions, with no observable increase in size
- severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- the 4th ventricle shows no notable changes suggestive of enlargement
- no evident size increase noted in the 3rd ventricle
- mild-to-moderate enlargement of the external csf
For the subcortical structures:
- mild-to-moderate atrophy of the left putamen; the right putamen is normal
- mild bilateral atrophy of the pallidum
- mild atrophy of the left thalamus; the right thalamus is normal
- mild-to-moderate atrophy of the left hippocampus
- moderate-to-severe atrophy of the left amygdala and mild atrophy of the right amygdala
- moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- mild atrophy of the left caudate; the right caudate is normal
For additional Regions of Interest:
- no evident atrophy or tissue thinning seen in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild-to-moderate atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- moderate atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) and mild atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild atrophy of the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus); the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) is normal
|
SV
|
ADNI_130_S_0886_MR_MPR__GradWarp__B1_Correction__N3__Scaled_Br_20070210214803504_S19561_I39171
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no observable enlargement of the inf. lateral ventricle
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
- mild-to-moderate enlargement of the external csf
- no appreciable enlargement noted in the 3rd ventricle
- lateral ventricle appears to be of normal dimensions, with no observable increase in size
For the subcortical structures:
- no clear atrophic alterations are visible in the caudate
- mild atrophy of the right hippocampus
- no evident atrophy or tissue thinning seen in the putamen
- no findings suggestive of atrophy are seen in the pallidum
- no appreciable degenerative or atrophic changes observed in the accumbens
- no evident atrophy or tissue thinning seen in the amygdala
- mild bilateral atrophy of the thalamus
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the temporal lobe
- insular cortex appears within normal limits without apparent atrophy
- no clear atrophic alterations are visible in the limbic cortex
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- frontal lobe appears within normal limits without apparent atrophy
- parietal lobe appears preserved, with no observable tissue loss
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) demonstrates a healthy morphology without signs of atrophy
- no clear atrophic alterations are visible in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- no clear atrophic alterations are visible in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) appears within normal limits without apparent atrophy
|
CN
|
FTLD_203723261_03162_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177101_dupl_6
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- moderate atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum
- moderate-to-severe atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
- moderate atrophy of the left caudate and mild atrophy of the right caudate
- moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- severe bilateral atrophy of the amygdala
- moderate-to-severe atrophy of the left hippocampus, moderate atrophy of the right hippocampus
- no evident atrophy or tissue thinning seen in the thalamus
For the cerebral cortex:
- severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate-to-severe atrophy on the left and moderate atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), planum polare (mild atrophy both left and right), sup. temporal gyrus (mild-to-moderate atrophy on the left) and planum temporale (mild atrophy on the left)
- mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), posterior insula (moderate atrophy both left and right) and central operculum (mild atrophy on the left)
- mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (mild-to-moderate atrophy on the left and normal on the right)
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- no clear atrophic alterations are visible in the parietal lobe
- mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: triangular inf. frontal gyrus (mild atrophy on the right), precentral gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right), medial frontal cortex (mild atrophy on the left and normal on the right) and anterior orbital gyrus (mild atrophy on the left)
For the ventricles:
- mild enlargement of the 3rd ventricle
- severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
- severe bilateral enlargement of the inf. lateral ventricle
- mild-to-moderate enlargement of the external csf
For additional Regions of Interest:
- mild atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) and mild-to-moderate atrophy of the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild-to-moderate atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) and mild atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- severe atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) and moderate atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild atrophy of the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus); the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) is normal
|
SV
|
FTLD_203505279_01970_MR_Sagittal_MP-Rage_br_raw_20230206175714863_I10182304
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no appreciable degenerative or atrophic changes observed in the frontal lobe
- mild atrophy of the right occipital lobe; normal-to-mild atrophy of the left occipital lobe; focal volume loss observed in the following subregions: occipital fusiform gyrus (normal on the left and mild atrophy on the right) and inf. occipital gyrus (normal on the left and mild atrophy on the right)
- temporal lobe demonstrates a healthy morphology without signs of atrophy
- parietal lobe maintains a normal appearance with no observable atrophic features
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (normal on the left and mild atrophy on the right) and frontal operculum (mild atrophy on the left and normal on the right)
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left) and middle cingulate gyrus (mild atrophy on the left)
For the subcortical structures:
- amygdala appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the caudate
- mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- mild-to-moderate atrophy of the left hippocampus
- the accumbens shows no notable changes suggestive of atrophy
- no evident atrophy or tissue thinning seen in the thalamus
- mild atrophy of the right putamen; the left putamen is normal
For the ventricles:
- inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size
- mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle
- no evident size increase noted in the 4th ventricle
- 3rd ventricle appears to be of normal dimensions, with no observable increase in size
- the external csf shows no notable changes suggestive of enlargement
For additional Regions of Interest:
- no clear atrophic alterations are visible in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) maintains a normal appearance with no observable atrophic features
- no observable atrophic changes in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) demonstrates a healthy morphology without signs of atrophy
|
CN
|
FTLD_203949588_01884_MR_Sagittal_MP-Rage_br_raw_20230206175408044_I10182283_dupl_1
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- moderate bilateral atrophy of the accumbens
- mild atrophy of the right thalamus; normal-to-mild atrophy of the left thalamus
- no findings suggestive of atrophy are seen in the amygdala
- mild atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
- moderate bilateral atrophy of the caudate
- mild atrophy of the right hippocampus
- moderate atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum
For the ventricles:
- mild enlargement of the 3rd ventricle
- mild enlargement of the external csf
- mild enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- mild-to-moderate enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle
- no evident size increase noted in the 4th ventricle
For the cerebral cortex:
- mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (mild-to-moderate atrophy both left and right) and posterior orbital gyrus (mild atrophy on the left)
- no evident atrophy or tissue thinning seen in the parietal lobe
- no appreciable degenerative or atrophic changes observed in the insular cortex
- no appreciable degenerative or atrophic changes observed in the temporal lobe
- the occipital lobe shows no notable changes suggestive of atrophy
- limbic cortex appears within normal limits without apparent atrophy
For additional Regions of Interest:
- mild atrophy of the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) is normal
- mild atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- no clear atrophic alterations are visible in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) shows no notable changes suggestive of atrophy
|
BV
|
FTLD_203928633_01332_MR_Sagittal_MP-Rage_br_raw_20230209091053341_I10182994
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the limbic cortex
- no observable atrophic changes in the frontal lobe
- insular cortex appears within normal limits without apparent atrophy
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: fusiform gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right)
- mild atrophy of the left occipital lobe; the right occipital lobe is normal; focal volume loss observed in the following subregions: lingual gyrus (mild atrophy on the left and normal on the right)
- no observable atrophic changes in the parietal lobe
For the ventricles:
- mild-to-moderate enlargement of the external csf
- inf. lateral ventricle appears within normal size limits with no apparent enlargement
- lateral ventricle maintains a typical volume without observable enlargement
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
- the 3rd ventricle shows no notable changes suggestive of enlargement
For the subcortical structures:
- mild atrophy of the left thalamus; the right thalamus is normal
- no findings suggestive of atrophy are seen in the hippocampus
- no evident atrophy or tissue thinning seen in the putamen
- the amygdala shows no notable changes suggestive of atrophy
- caudate appears within normal limits without apparent atrophy
- pallidum maintains a normal appearance with no observable atrophic features
- mild bilateral atrophy of the accumbens
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) maintains a normal appearance with no observable atrophic features
- no evident atrophy or tissue thinning seen in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- mild atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala); the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) is normal
- no observable atrophic changes in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
CN
|
FTLD_203158026_03625_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047629_dupl_11
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild enlargement of the 3rd ventricle
- no appreciable enlargement noted in the 4th ventricle
- no findings suggestive of enlargement are seen in the external csf
- the lateral ventricle shows no notable changes suggestive of enlargement
- inf. lateral ventricle maintains a typical volume without observable enlargement
For the subcortical structures:
- hippocampus appears preserved, with no observable tissue loss
- mild atrophy of the left putamen; the right putamen is normal
- mild atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- caudate appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the amygdala
- thalamus maintains a normal appearance with no observable atrophic features
- mild bilateral atrophy of the pallidum
For the cerebral cortex:
- the parietal lobe shows no notable changes suggestive of atrophy
- the frontal lobe shows no notable changes suggestive of atrophy
- no evident atrophy or tissue thinning seen in the temporal lobe
- occipital lobe appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the limbic cortex
- no evident atrophy or tissue thinning seen in the insular cortex
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) appears preserved, with no observable tissue loss
- salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) demonstrates a healthy morphology without signs of atrophy
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) appears preserved, with no observable tissue loss
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) appears preserved, with no observable tissue loss
|
PNFA
|
ADNI_098_S_10633_MR_Accelerated_Sagittal_MPRAGE_MSV22_br_raw_20250610191045026_1_I11311283
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild atrophy of the left accumbens; normal-to-mild atrophy of the right accumbens
- no clear atrophic alterations are visible in the pallidum
- no appreciable degenerative or atrophic changes observed in the hippocampus
- no evident atrophy or tissue thinning seen in the caudate
- mild bilateral atrophy of the putamen
- mild atrophy of the right amygdala; the left amygdala is normal
- no observable atrophic changes in the thalamus
For the ventricles:
- no findings suggestive of enlargement are seen in the 4th ventricle
- the external csf shows no notable changes suggestive of enlargement
- inf. lateral ventricle maintains a typical volume without observable enlargement
- no appreciable enlargement noted in the 3rd ventricle
- no clear enlargement or abnormal growth seen in the lateral ventricle
For the cerebral cortex:
- mild-to-moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: inf. temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal on the right), planum polare (normal-to-mild atrophy on the left and mild atrophy on the right) and temporal pole (mild atrophy on the left and normal on the right)
- insular cortex appears within normal limits without apparent atrophy
- mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: medial frontal cortex (mild atrophy both left and right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus (normal on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy on the left) and lateral orbital gyrus (mild atrophy on the left)
- no evident atrophy or tissue thinning seen in the occipital lobe
- the limbic cortex shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the parietal lobe
For additional Regions of Interest:
- mild atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) is normal
- no evident atrophy or tissue thinning seen in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- mild bilateral atrophy of the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) shows no notable changes suggestive of atrophy
|
CN
|
FTLD_203540027_02724_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177236_dupl_4
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild-to-moderate enlargement of the 4th ventricle
- mild enlargement of the external csf
- mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- severe enlargement of the 3rd ventricle
For the subcortical structures:
- moderate atrophy of the left hippocampus, mild-to-moderate atrophy of the right hippocampus
- mild-to-moderate atrophy of the left putamen; the right putamen is normal
- mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- mild-to-moderate atrophy of the left caudate and mild atrophy of the right caudate
- severe atrophy of the left amygdala and moderate atrophy of the right amygdala
- no findings suggestive of atrophy are seen in the thalamus
- mild atrophy of the left pallidum; the right pallidum is normal
For the cerebral cortex:
- limbic cortex maintains a normal appearance with no observable atrophic features
- frontal lobe appears within normal limits without apparent atrophy
- severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy both left and right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. temporal gyrus (mild atrophy on the left and normal on the right) and planum temporale (mild atrophy on the left)
- occipital lobe appears preserved, with no observable tissue loss
- no findings suggestive of atrophy are seen in the parietal lobe
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and normal-to-mild atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right), frontal operculum (mild-to-moderate atrophy on the right) and parietal operculum (mild atrophy on the left and normal on the right)
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- severe atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) and moderate atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- no clear atrophic alterations are visible in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
SV
|
FTLD_203240205_03504_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450857_dupl_13
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: frontal pole (mild atrophy both left and right), opercular inf. frontal gyrus (mild atrophy both left and right), medial frontal cortex (mild atrophy both left and right), medial orbital gyrus (mild atrophy both left and right), middle frontal gyrus (mild atrophy on the right), subcallosal area (normal on the left and mild atrophy on the right), posterior orbital gyrus (mild atrophy on the left), precentral gyrus (mild atrophy on the left) and sup. frontal gyrus (mild atrophy on the left)
- no observable atrophic changes in the temporal lobe
- mild-to-moderate atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: postcentral gyrus medial segment (mild atrophy both left and right), precuneus (mild-to-moderate atrophy on the left and normal on the right), supramarginal gyrus (mild atrophy on the left), angular gyrus (normal on the left and mild atrophy on the right) and postcentral gyrus (mild atrophy on the left and normal on the right)
- mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal on the left and mild atrophy on the right) and parahippocampal gyrus (mild atrophy on the left and normal on the right)
- the insular cortex shows no notable changes suggestive of atrophy
- no observable atrophic changes in the occipital lobe
For the subcortical structures:
- mild bilateral atrophy of the thalamus
- pallidum maintains a normal appearance with no observable atrophic features
- no appreciable degenerative or atrophic changes observed in the caudate
- amygdala appears within normal limits without apparent atrophy
- no observable atrophic changes in the putamen
- the accumbens shows no notable changes suggestive of atrophy
- no observable atrophic changes in the hippocampus
For the ventricles:
- no observable enlargement of the 3rd ventricle
- moderate enlargement of the external csf
- inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size
- no appreciable enlargement noted in the 4th ventricle
- lateral ventricle appears within normal size limits with no apparent enlargement
For additional Regions of Interest:
- mild atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) is normal
- mild bilateral atrophy of the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) demonstrates a healthy morphology without signs of atrophy
- mild bilateral atrophy of the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
PNFA
|
ADNI_019_S_4835_MR_MPRAGE_br_raw_20130730164857256_97_S196967_I383444
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- the hippocampus shows no notable changes suggestive of atrophy
- putamen appears within normal limits without apparent atrophy
- no appreciable degenerative or atrophic changes observed in the caudate
- no clear atrophic alterations are visible in the pallidum
- no findings suggestive of atrophy are seen in the thalamus
- no findings suggestive of atrophy are seen in the amygdala
- the accumbens shows no notable changes suggestive of atrophy
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the temporal lobe
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- insular cortex appears within normal limits without apparent atrophy
- limbic cortex appears within normal limits without apparent atrophy
- no appreciable degenerative or atrophic changes observed in the frontal lobe
For the ventricles:
- no observable enlargement of the external csf
- lateral ventricle maintains a typical volume without observable enlargement
- 3rd ventricle maintains a typical volume without observable enlargement
- no clear enlargement or abnormal growth seen in the inf. lateral ventricle
- no findings suggestive of enlargement are seen in the 4th ventricle
For additional Regions of Interest:
- no evident atrophy or tissue thinning seen in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) demonstrates a healthy morphology without signs of atrophy
- no evident atrophy or tissue thinning seen in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) appears within normal limits without apparent atrophy
|
CN
|
FTLD_203023197_01792_MR_Sagittal_MP-Rage_br_raw_20230209092223055_I10183099_dupl_3
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- moderate-to-severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate-to-severe atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (moderate atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy both left and right), gyrus rectus (mild-to-moderate atrophy on the left), precentral gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), frontal pole (mild atrophy on the left and normal on the right), medial frontal cortex (mild atrophy on the left) and lateral orbital gyrus (mild atrophy on the left and normal on the right)
- mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right) and frontal operculum (mild atrophy both left and right)
- mild-to-moderate atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: postcentral gyrus medial segment (mild atrophy on the left), angular gyrus (mild atrophy on the left), supramarginal gyrus (mild atrophy on the left and normal on the right), precuneus (mild atrophy on the left) and sup. parietal lobule (mild atrophy on the left)
- occipital lobe appears preserved, with no observable tissue loss
- limbic cortex appears within normal limits without apparent atrophy
- no appreciable degenerative or atrophic changes observed in the temporal lobe
For the ventricles:
- 4th ventricle appears within normal size limits with no apparent enlargement
- severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
- moderate enlargement of the external csf
- severe enlargement of the 3rd ventricle
For the subcortical structures:
- hippocampus maintains a normal appearance with no observable atrophic features
- moderate atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
- moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus
- severe atrophy of the left caudate and moderate atrophy of the right caudate
- amygdala appears preserved, with no observable tissue loss
- moderate atrophy of the left pallidum and mild atrophy of the right pallidum
For additional Regions of Interest:
- mild-to-moderate bilateral atrophy of the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild-to-moderate atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- no observable atrophic changes in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild atrophy of the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus); normal-to-mild atrophy of the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
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SV
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ADNI_114_S_6309_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180504142331759_89_S682445_I992776
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On a T1-weighted brain MRI we observed:
For the ventricles:
- external csf appears to be of normal dimensions, with no observable increase in size
- mild enlargement of the 3rd ventricle
- mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- 4th ventricle maintains a typical volume without observable enlargement
- lateral ventricle appears within normal size limits with no apparent enlargement
For the cerebral cortex:
- insular cortex appears preserved, with no observable tissue loss
- no findings suggestive of atrophy are seen in the frontal lobe
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle cingulate gyrus (mild atrophy on the left and normal on the right)
- no clear atrophic alterations are visible in the occipital lobe
- no appreciable degenerative or atrophic changes observed in the temporal lobe
- parietal lobe maintains a normal appearance with no observable atrophic features
For the subcortical structures:
- pallidum demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the hippocampus
- no appreciable degenerative or atrophic changes observed in the caudate
- the amygdala shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the putamen
- mild bilateral atrophy of the accumbens
- the thalamus shows no notable changes suggestive of atrophy
For additional Regions of Interest:
- no appreciable degenerative or atrophic changes observed in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild-to-moderate atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); normal-to-mild atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
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CN
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ADNI_129_S_6704_MR_Accelerated_Sag_IR-FSPGR___br_raw_20190401061925402_196_S811320_I1149034
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On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no observable atrophic changes in the insular cortex
- no findings suggestive of atrophy are seen in the limbic cortex
- parietal lobe maintains a normal appearance with no observable atrophic features
- frontal lobe maintains a normal appearance with no observable atrophic features
- occipital lobe appears preserved, with no observable tissue loss
- temporal lobe maintains a normal appearance with no observable atrophic features
For the ventricles:
- no observable enlargement of the 4th ventricle
- external csf maintains a typical volume without observable enlargement
- no findings suggestive of enlargement are seen in the inf. lateral ventricle
- lateral ventricle appears to be of normal dimensions, with no observable increase in size
- 3rd ventricle appears within normal size limits with no apparent enlargement
For the subcortical structures:
- amygdala maintains a normal appearance with no observable atrophic features
- the hippocampus shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the putamen
- caudate appears preserved, with no observable tissue loss
- thalamus appears preserved, with no observable tissue loss
- the accumbens shows no notable changes suggestive of atrophy
- the pallidum shows no notable changes suggestive of atrophy
For additional Regions of Interest:
- no findings suggestive of atrophy are seen in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- no evident atrophy or tissue thinning seen in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- no findings suggestive of atrophy are seen in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
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CN
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FTLD_203798227_03729_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10451111_dupl_5
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On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the occipital lobe
- moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild-to-moderate atrophy on the left and mild atrophy on the right), medial frontal cortex (mild atrophy both left and right), middle frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), medial orbital gyrus (mild atrophy on the left), precentral gyrus (mild atrophy on the left) and precentral gyrus medial segment (mild atrophy on the left)
- parietal lobe maintains a normal appearance with no observable atrophic features
- severe atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (severe atrophy both left and right), inf. temporal gyrus (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate atrophy on the left and mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. temporal gyrus (moderate atrophy on the left) and planum polare (mild-to-moderate atrophy on the left and normal on the right)
- moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy both left and right), anterior cingulate gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle cingulate gyrus (mild-to-moderate atrophy on the left) and parahippocampal gyrus (mild atrophy on the left)
- moderate-to-severe atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate atrophy on the right), posterior insula (moderate atrophy on the left and mild atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left and normal on the right), central operculum (mild atrophy on the left and normal on the right) and parietal operculum (normal on the left and mild atrophy on the right)
For the ventricles:
- mild-to-moderate enlargement of the external csf
- severe bilateral enlargement of the lateral ventricle
- moderate-to-severe enlargement of the 3rd ventricle
- 4th ventricle maintains its expected proportions without signs of enlargement
- severe bilateral enlargement of the inf. lateral ventricle
For the subcortical structures:
- severe atrophy of the left putamen and moderate atrophy of the right putamen
- severe bilateral atrophy of the amygdala
- severe atrophy of the left hippocampus, mild-to-moderate atrophy of the right hippocampus
- severe atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- moderate atrophy of the left pallidum and mild atrophy of the right pallidum
- moderate-to-severe atrophy of the left caudate and mild-to-moderate atrophy of the right caudate
- mild-to-moderate atrophy of the left thalamus; the right thalamus is normal
For additional Regions of Interest:
- mild-to-moderate atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) is normal
- moderate atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) and mild-to-moderate atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- severe atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) and moderate atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild-to-moderate atrophy of the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus); the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) is normal
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SV
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ADNI_941_S_10001_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20231017152120602_1_I10280538_dupl_1
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On a T1-weighted brain MRI we observed:
For the ventricles:
- mild enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- mild enlargement of the external csf
- moderate enlargement of the 3rd ventricle
- no clear enlargement or abnormal growth seen in the 4th ventricle
For the subcortical structures:
- the accumbens shows no notable changes suggestive of atrophy
- mild bilateral atrophy of the putamen
- mild atrophy of the left hippocampus, moderate atrophy of the right hippocampus
- pallidum demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the right caudate; normal-to-mild atrophy of the left caudate
- no appreciable degenerative or atrophic changes observed in the thalamus
- moderate atrophy of the left amygdala and severe atrophy of the right amygdala
For the cerebral cortex:
- mild atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (normal on the left and moderate atrophy on the right), anterior cingulate gyrus (mild atrophy both left and right) and parahippocampal gyrus (normal on the left and mild atrophy on the right)
- moderate atrophy of the right occipital lobe; the left occipital lobe is normal; focal volume loss observed in the following subregions: middle occipital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), cuneus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and inf. occipital gyrus (normal on the left and mild atrophy on the right)
- moderate bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), planum temporale (mild atrophy both left and right), temporal pole (mild atrophy both left and right), inf. temporal gyrus (mild atrophy both left and right), middle temporal gyrus (mild atrophy both left and right), sup. temporal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and transverse temporal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right)
- no findings suggestive of atrophy are seen in the parietal lobe
- mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: sup. frontal gyrus (mild atrophy both left and right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right), opercular inf. frontal gyrus (normal on the left and mild atrophy on the right) and middle frontal gyrus (normal on the left and mild atrophy on the right)
- mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left and right), posterior insula (mild atrophy both left and right), central operculum (mild atrophy on the left and normal on the right) and parietal operculum (normal on the left and mild atrophy on the right)
For additional Regions of Interest:
- no evident atrophy or tissue thinning seen in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) and mild-to-moderate atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- moderate bilateral atrophy of the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild-to-moderate atrophy of the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus); normal-to-mild atrophy of the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
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AD
|
ADNI_037_S_6377_MR_Accelerated_Sagittal_MPRAGE__br_raw_20180706142306729_62_S701869_I1017725_dupl_3
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On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild atrophy of the left accumbens; the right accumbens is normal
- putamen demonstrates a healthy morphology without signs of atrophy
- no evident atrophy or tissue thinning seen in the caudate
- moderate atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala
- mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum
- thalamus appears preserved, with no observable tissue loss
- hippocampus demonstrates a healthy morphology without signs of atrophy
For the ventricles:
- mild-to-moderate bilateral enlargement of the inf. lateral ventricle
- external csf appears to be of normal dimensions, with no observable increase in size
- no evident size increase noted in the lateral ventricle
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
- no appreciable enlargement noted in the 3rd ventricle
For the cerebral cortex:
- the insular cortex shows no notable changes suggestive of atrophy
- parietal lobe appears within normal limits without apparent atrophy
- no observable atrophic changes in the occipital lobe
- temporal lobe appears within normal limits without apparent atrophy
- limbic cortex appears preserved, with no observable tissue loss
- frontal lobe appears preserved, with no observable tissue loss
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
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AD
|
FTLD_203905200_03000_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177904_dupl_1
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- moderate enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle
- moderate enlargement of the 3rd ventricle
- severe bilateral enlargement of the lateral ventricle
- no findings suggestive of enlargement are seen in the 4th ventricle
- severe enlargement of the external csf
For the cerebral cortex:
- occipital lobe maintains a normal appearance with no observable atrophic features
- moderate atrophy of the left frontal lobe and severe atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), lateral orbital gyrus (moderate atrophy both left and right), middle frontal gyrus (moderate atrophy both left and right), orbital inf. frontal gyrus (mild atrophy on the left and moderate atrophy on the right), medial orbital gyrus (mild atrophy on the left and moderate atrophy on the right), posterior orbital gyrus (mild atrophy on the left and moderate atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (mild atrophy both left and right), medial frontal cortex (normal on the left and moderate atrophy on the right), sup. frontal gyrus medial segment (moderate atrophy on the right), frontal pole (mild-to-moderate atrophy on the right), anterior orbital gyrus (normal on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (normal on the left and mild-to-moderate atrophy on the right) and subcallosal area (normal-to-mild atrophy on the left and mild atrophy on the right)
- moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and severe atrophy on the right), posterior insula (mild-to-moderate atrophy on the left and moderate atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left and moderate atrophy on the right) and central operculum (mild atrophy on the right)
- no evident atrophy or tissue thinning seen in the parietal lobe
- mild atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (normal on the left and moderate-to-severe atrophy on the right), fusiform gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (normal on the left and moderate atrophy on the right), temporal pole (normal on the left and moderate atrophy on the right) and transverse temporal gyrus (mild-to-moderate atrophy on the left and normal on the right)
- moderate bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate-to-severe atrophy on the left and moderate atrophy on the right), middle cingulate gyrus (mild atrophy both left and right), parahippocampal gyrus (mild atrophy both left and right) and entorhinal area (mild atrophy on the right)
For the subcortical structures:
- severe bilateral atrophy of the caudate
- mild atrophy of the left thalamus and mild-to-moderate atrophy of the right thalamus
- moderate atrophy of the left amygdala and severe atrophy of the right amygdala
- mild-to-moderate atrophy of the right hippocampus
- mild atrophy of the left pallidum and moderate atrophy of the right pallidum
- moderate-to-severe atrophy of the left putamen and severe atrophy of the right putamen
- severe bilateral atrophy of the accumbens
For additional Regions of Interest:
- mild atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) and moderate atrophy of the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- severe bilateral atrophy of the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- mild atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) and severe atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild atrophy of the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus); the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) is normal
|
BV
|
ADNI_011_S_0008_MR_MPR-R__GradWarp__B1_Correction__N3__Scaled_Br_20061208113853608_S9195_I32264
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: transverse temporal gyrus (mild atrophy both left and right), fusiform gyrus (mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right)
- parietal lobe appears preserved, with no observable tissue loss
- the frontal lobe shows no notable changes suggestive of atrophy
- mild atrophy of the left occipital lobe; the right occipital lobe is normal; focal volume loss observed in the following subregions: occipital pole (mild atrophy both left and right) and middle occipital gyrus (mild atrophy on the left)
- the insular cortex shows no notable changes suggestive of atrophy
- limbic cortex appears within normal limits without apparent atrophy
For the ventricles:
- 4th ventricle maintains a typical volume without observable enlargement
- no evident size increase noted in the 3rd ventricle
- no findings suggestive of enlargement are seen in the lateral ventricle
- no observable enlargement of the external csf
- the inf. lateral ventricle shows no notable changes suggestive of enlargement
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the putamen
- thalamus appears within normal limits without apparent atrophy
- mild-to-moderate atrophy of the right hippocampus
- caudate appears preserved, with no observable tissue loss
- accumbens appears preserved, with no observable tissue loss
- mild atrophy of the right amygdala; the left amygdala is normal
- pallidum appears preserved, with no observable tissue loss
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) appears preserved, with no observable tissue loss
- no clear atrophic alterations are visible in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) maintains a normal appearance with no observable atrophic features
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) appears within normal limits without apparent atrophy
|
CN
|
ADNI_036_S_6887_MR_Accelerated_Sagittal_MPRAGE_MSV21_br_raw_20240720184701443_1_I10883435_dupl_2
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no evident size increase noted in the external csf
- severe enlargement of the 4th ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- severe bilateral enlargement of the lateral ventricle
- severe enlargement of the 3rd ventricle
For the subcortical structures:
- no evident atrophy or tissue thinning seen in the thalamus
- mild bilateral atrophy of the amygdala
- mild atrophy of the left hippocampus, mild-to-moderate atrophy of the right hippocampus
- mild-to-moderate bilateral atrophy of the accumbens
- no evident atrophy or tissue thinning seen in the pallidum
- mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen
- mild-to-moderate bilateral atrophy of the caudate
For the cerebral cortex:
- mild-to-moderate bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (moderate atrophy both left and right), sup. temporal gyrus (mild-to-moderate atrophy both left and right) and planum temporale (mild atrophy on the left and normal on the right)
- mild atrophy of the right frontal lobe; normal-to-mild atrophy of the left frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left and right), posterior orbital gyrus (normal on the left and mild-to-moderate atrophy on the right), opercular inf. frontal gyrus (normal on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the right) and gyrus rectus (mild atrophy on the left)
- moderate atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: posterior insula (mild atrophy both left and right), central operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right), anterior insula (mild atrophy on the left and normal on the right) and frontal operculum (normal on the left and mild atrophy on the right)
- mild bilateral atrophy of the occipital lobe; focal volume loss observed in the following subregions: inf. occipital gyrus (mild atrophy both left and right), middle occipital gyrus (mild atrophy both left and right), occipital pole (mild atrophy on the left and normal-to-mild atrophy on the right), calcarine cortex (mild atrophy on the left and normal on the right) and cuneus (mild atrophy on the left and normal on the right)
- mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right)
- mild atrophy of the right parietal lobe; the left parietal lobe is normal; focal volume loss observed in the following subregions: postcentral gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right) and supramarginal gyrus (mild atrophy on the left and normal on the right)
For additional Regions of Interest:
- no clear atrophic alterations are visible in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild-to-moderate bilateral atrophy of the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) appears preserved, with no observable tissue loss
- no clear atrophic alterations are visible in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
AD
|
ADNI_021_S_10161_MR_Accelerated_Sag_IR-FSPGR_MSV21_br_raw_20240806184357408_1_I10908334
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no clear enlargement or abnormal growth seen in the external csf
- no observable enlargement of the 3rd ventricle
- lateral ventricle maintains its expected proportions without signs of enlargement
- no appreciable enlargement noted in the inf. lateral ventricle
- no evident size increase noted in the 4th ventricle
For the cerebral cortex:
- limbic cortex appears preserved, with no observable tissue loss
- mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy on the right), central operculum (normal on the left and mild atrophy on the right), frontal operculum (mild atrophy on the left and normal on the right) and parietal operculum (normal on the left and mild atrophy on the right)
- frontal lobe demonstrates a healthy morphology without signs of atrophy
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- no observable atrophic changes in the parietal lobe
- the temporal lobe shows no notable changes suggestive of atrophy
For the subcortical structures:
- pallidum appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the caudate
- no appreciable degenerative or atrophic changes observed in the amygdala
- no evident atrophy or tissue thinning seen in the accumbens
- no findings suggestive of atrophy are seen in the thalamus
- the putamen shows no notable changes suggestive of atrophy
- hippocampus maintains a normal appearance with no observable atrophic features
For additional Regions of Interest:
- mild atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) is normal
- no findings suggestive of atrophy are seen in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
CN
|
FTLD_203099329_02929_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178261_dupl_3
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy both left and right) and middle cingulate gyrus (normal on the left and mild atrophy on the right)
- mild-to-moderate atrophy of the left parietal lobe and mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), precuneus (mild atrophy on the left and normal on the right) and supramarginal gyrus (mild atrophy on the left and normal on the right)
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy both left and right), parietal operculum (mild atrophy both left and right), frontal operculum (mild atrophy both left and right), posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right) and central operculum (normal on the left and mild atrophy on the right)
- mild-to-moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right), inf. temporal gyrus (mild atrophy on the left and normal on the right) and sup. temporal gyrus (mild atrophy on the left and normal on the right)
- moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), frontal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (moderate atrophy on the left and normal on the right), lateral orbital gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), gyrus rectus (normal on the left and mild-to-moderate atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left and normal on the right) and sup. frontal gyrus medial segment (mild atrophy on the left and normal on the right)
For the subcortical structures:
- mild atrophy of the left amygdala; the right amygdala is normal
- mild atrophy of the left hippocampus
- thalamus maintains a normal appearance with no observable atrophic features
- moderate bilateral atrophy of the caudate
- pallidum appears within normal limits without apparent atrophy
- mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen
- mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens
For the ventricles:
- mild-to-moderate bilateral enlargement of the lateral ventricle
- mild enlargement of the 3rd ventricle
- moderate enlargement of the external csf
- mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- no clear enlargement or abnormal growth seen in the 4th ventricle
For additional Regions of Interest:
- mild atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); normal-to-mild atrophy of the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- moderate bilateral atrophy of the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- mild bilateral atrophy of the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild-to-moderate atrophy of the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) and mild atrophy of the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
BV
|
FTLD_203762465_03566_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047585_dupl_1
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no evident atrophy or tissue thinning seen in the insular cortex
- no findings suggestive of atrophy are seen in the occipital lobe
- mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left and right) and middle cingulate gyrus (mild atrophy both left and right)
- the temporal lobe shows no notable changes suggestive of atrophy
- mild-to-moderate atrophy of the left parietal lobe and moderate atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left and right), sup. parietal lobule (mild atrophy both left and right), precuneus (normal-to-mild atrophy on the left and mild atrophy on the right) and postcentral gyrus (normal on the left and mild atrophy on the right)
- mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), orbital inf. frontal gyrus (mild atrophy on the left and normal on the right), gyrus rectus (normal on the left and mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and normal on the right) and posterior orbital gyrus (normal on the left and mild atrophy on the right)
For the ventricles:
- mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle
- moderate enlargement of the external csf
- mild enlargement of the 3rd ventricle
- 4th ventricle maintains its expected proportions without signs of enlargement
- mild-to-moderate enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
For the subcortical structures:
- mild atrophy of the left caudate and mild-to-moderate atrophy of the right caudate
- mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen
- no observable atrophic changes in the amygdala
- early/mild-grade volumetric reduction of the right hippocampus
- mild atrophy of the left thalamus; the right thalamus is normal
For additional Regions of Interest:
- mild atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) is normal
- mild bilateral atrophy of the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- mild atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala); normal-to-mild atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild atrophy of the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) and mild-to-moderate atrophy of the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
BV
|
ADNI_123_S_0091_MR_MPR____N3__Scaled_Br_20070802215937761_S10708_I64405_dupl_1
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- accumbens demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the amygdala
- hippocampus maintains a normal appearance with no observable atrophic features
- pallidum demonstrates a healthy morphology without signs of atrophy
- the caudate shows no notable changes suggestive of atrophy
- putamen appears within normal limits without apparent atrophy
- no appreciable degenerative or atrophic changes observed in the thalamus
For the cerebral cortex:
- mild-to-moderate atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: postcentral gyrus (mild atrophy both left and right) and angular gyrus (mild atrophy on the left and normal on the right)
- mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left and right), subcallosal area (mild atrophy both left and right), supplementary motor cortex (mild atrophy both left and right), sup. frontal gyrus (normal on the left and mild atrophy on the right) and orbital inf. frontal gyrus (mild atrophy on the right)
- no evident atrophy or tissue thinning seen in the occipital lobe
- mild-to-moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: sup. temporal gyrus (mild atrophy on the left and normal on the right), middle temporal gyrus (mild atrophy on the left) and planum polare (normal on the left and mild atrophy on the right)
- limbic cortex appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the insular cortex
For the ventricles:
- mild enlargement of the external csf
- 3rd ventricle maintains a typical volume without observable enlargement
- the inf. lateral ventricle shows no notable changes suggestive of enlargement
- no evident size increase noted in the 4th ventricle
- no findings suggestive of enlargement are seen in the lateral ventricle
For additional Regions of Interest:
- mild atrophy of the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); normal-to-mild atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) maintains a normal appearance with no observable atrophic features
- mild atrophy of the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus); the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) is normal
|
AD
|
ADNI_098_S_4018_MR_Accelerated_Sag_IR-SPGR__br_raw_20110422173143430_59_S105026_I228789
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild-to-moderate enlargement of the 3rd ventricle
- mild enlargement of the 4th ventricle
- moderate enlargement of the external csf
- no findings suggestive of enlargement are seen in the lateral ventricle
- no clear enlargement or abnormal growth seen in the inf. lateral ventricle
For the cerebral cortex:
- the frontal lobe shows no notable changes suggestive of atrophy
- the insular cortex shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- no observable atrophic changes in the limbic cortex
- temporal lobe maintains a normal appearance with no observable atrophic features
- mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left and right) and postcentral gyrus (normal on the left and mild atrophy on the right)
For the subcortical structures:
- no clear atrophic alterations are visible in the accumbens
- no findings suggestive of atrophy are seen in the hippocampus
- mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate
- pallidum appears preserved, with no observable tissue loss
- the amygdala shows no notable changes suggestive of atrophy
- mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen
- mild atrophy of the right thalamus; normal-to-mild atrophy of the left thalamus
For additional Regions of Interest:
- no appreciable degenerative or atrophic changes observed in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); normal-to-mild atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- no findings suggestive of atrophy are seen in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
CN
|
FTLD_203021096_03692_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10451067_dupl_3
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- caudate appears within normal limits without apparent atrophy
- mild-to-moderate bilateral atrophy of the putamen
- mild bilateral atrophy of the amygdala
- mild bilateral atrophy of the accumbens
- no evident atrophy or tissue thinning seen in the thalamus
- mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- no evident atrophy or tissue thinning seen in the hippocampus
For the ventricles:
- 4th ventricle maintains its expected proportions without signs of enlargement
- no observable enlargement of the external csf
- mild-to-moderate enlargement of the right inf. lateral ventricle; normal-to-mild enlargement of the left inf. lateral ventricle
- no findings suggestive of enlargement are seen in the 3rd ventricle
- mild-to-moderate bilateral enlargement of the lateral ventricle
For the cerebral cortex:
- the temporal lobe shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the parietal lobe
- no evident atrophy or tissue thinning seen in the occipital lobe
- no observable atrophic changes in the insular cortex
- no evident atrophy or tissue thinning seen in the frontal lobe
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and normal on the right) and posterior cingulate gyrus (mild atrophy on the left and normal on the right)
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) appears within normal limits without apparent atrophy
- salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) maintains a normal appearance with no observable atrophic features
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) appears within normal limits without apparent atrophy
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) demonstrates a healthy morphology without signs of atrophy
|
SV
|
FTLD_203212277_03771_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451144_dupl_5
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- external csf appears within normal size limits with no apparent enlargement
- severe bilateral enlargement of the inf. lateral ventricle
- mild enlargement of the 3rd ventricle
- mild enlargement of the left lateral ventricle; the right lateral ventricle is normal
- the 4th ventricle shows no notable changes suggestive of enlargement
For the cerebral cortex:
- moderate-to-severe atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and mild atrophy on the right), posterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right) and parietal operculum (mild atrophy on the left)
- severe atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (moderate atrophy on the left and mild atrophy on the right), temporal pole (severe atrophy on the left and normal on the right), fusiform gyrus (moderate atrophy on the left and normal on the right) and inf. temporal gyrus (moderate atrophy on the left)
- no clear atrophic alterations are visible in the occipital lobe
- moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and mild atrophy on the right), parahippocampal gyrus (mild atrophy both left and right), middle cingulate gyrus (mild atrophy on the left), anterior cingulate gyrus (mild-to-moderate atrophy on the left) and posterior cingulate gyrus (mild atrophy on the left and normal on the right)
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- no observable atrophic changes in the frontal lobe
For the subcortical structures:
- thalamus appears within normal limits without apparent atrophy
- severe atrophy of the left amygdala and moderate atrophy of the right amygdala
- moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- mild atrophy of the left putamen; the right putamen is normal
- mild-to-moderate atrophy of the left caudate; normal-to-mild atrophy of the right caudate
- severe atrophy of the left hippocampus
- no clear atrophic alterations are visible in the pallidum
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) appears preserved, with no observable tissue loss
- moderate-to-severe atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- severe atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala); normal-to-mild atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild-to-moderate atrophy of the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus); normal-to-mild atrophy of the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
SV
|
FTLD_203830616_02613_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177715_dupl_8
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the parietal lobe shows no notable changes suggestive of atrophy
- frontal lobe maintains a normal appearance with no observable atrophic features
- moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right), sup. temporal gyrus (mild atrophy on the left), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and planum polare (mild atrophy on the left and normal on the right)
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal on the right), posterior insula (mild atrophy on the left and normal on the right) and central operculum (mild atrophy on the left)
- no clear atrophic alterations are visible in the occipital lobe
- the limbic cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in entorhinal area (moderate atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (mild atrophy both left and right)
For the subcortical structures:
- mild-to-moderate atrophy of the left hippocampus, mild atrophy of the right hippocampus
- mild atrophy of the left putamen; the right putamen is normal
- mild atrophy of the left accumbens; the right accumbens is normal
- severe atrophy of the left amygdala and moderate atrophy of the right amygdala
- no clear atrophic alterations are visible in the thalamus
- the pallidum shows no notable changes suggestive of atrophy
- mild bilateral atrophy of the caudate
For the ventricles:
- no evident size increase noted in the 4th ventricle
- 3rd ventricle appears to be of normal dimensions, with no observable increase in size
- severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
- mild enlargement of the left lateral ventricle; the right lateral ventricle is normal
- external csf appears within normal size limits with no apparent enlargement
For additional Regions of Interest:
- the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- moderate-to-severe atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) and mild atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
SV
|
ADNI_021_S_4421_MR_Accelerated_Sag_IR-SPGR__br_raw_20111221105845600_170_S134211_I273577
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild bilateral atrophy of the putamen
- no clear atrophic alterations are visible in the accumbens
- hippocampus appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the thalamus
- caudate appears preserved, with no observable tissue loss
- no findings suggestive of atrophy are seen in the pallidum
- amygdala appears within normal limits without apparent atrophy
For the ventricles:
- the inf. lateral ventricle shows no notable changes suggestive of enlargement
- external csf maintains its expected proportions without signs of enlargement
- no observable enlargement of the 4th ventricle
- no appreciable enlargement noted in the lateral ventricle
- the 3rd ventricle shows no notable changes suggestive of enlargement
For the cerebral cortex:
- no appreciable degenerative or atrophic changes observed in the frontal lobe
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy on the left)
- temporal lobe maintains a normal appearance with no observable atrophic features
- insular cortex appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the parietal lobe
- no evident atrophy or tissue thinning seen in the occipital lobe
For additional Regions of Interest:
- no appreciable degenerative or atrophic changes observed in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) appears preserved, with no observable tissue loss
- no observable atrophic changes in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) appears within normal limits without apparent atrophy
|
CN
|
ADNI_130_S_4352_MR_MPRAGE_br_raw_20111121102623843_152_S130237_I267711
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no observable atrophic changes in the occipital lobe
- mild atrophy of the right parietal lobe; the left parietal lobe is normal; focal volume loss observed in the following subregions: postcentral gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right)
- no clear atrophic alterations are visible in the frontal lobe
- temporal lobe maintains a normal appearance with no observable atrophic features
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: middle cingulate gyrus (mild atrophy on the left and normal-to-mild atrophy on the right) and anterior cingulate gyrus (normal on the left and mild atrophy on the right)
- no appreciable degenerative or atrophic changes observed in the insular cortex
For the subcortical structures:
- no evident atrophy or tissue thinning seen in the amygdala
- no clear atrophic alterations are visible in the pallidum
- putamen appears preserved, with no observable tissue loss
- mild bilateral atrophy of the caudate
- no evident atrophy or tissue thinning seen in the thalamus
- accumbens maintains a normal appearance with no observable atrophic features
- mild atrophy of the left hippocampus
For the ventricles:
- lateral ventricle maintains its expected proportions without signs of enlargement
- mild enlargement of the 3rd ventricle
- mild-to-moderate enlargement of the external csf
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
- inf. lateral ventricle maintains its expected proportions without signs of enlargement
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) appears preserved, with no observable tissue loss
- salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) demonstrates a healthy morphology without signs of atrophy
|
CN
|
FTLD_203260125_02526_MR_Sagittal_MP-Rage_br_raw_20230206161248652_I10181566_dupl_9
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- moderate-to-severe enlargement of the 3rd ventricle
- mild-to-moderate enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- mild-to-moderate enlargement of the external csf
- moderate-to-severe enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle
- mild enlargement of the 4th ventricle
For the subcortical structures:
- no clear atrophic alterations are visible in the putamen
- mild bilateral atrophy of the thalamus
- no clear atrophic alterations are visible in the hippocampus
- mild bilateral atrophy of the accumbens
- the pallidum shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the amygdala
- mild atrophy of the left caudate and mild-to-moderate atrophy of the right caudate
For the cerebral cortex:
- no observable atrophic changes in the limbic cortex
- no evident atrophy or tissue thinning seen in the parietal lobe
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- moderate bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (mild-to-moderate atrophy both left and right), precentral gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right), precentral gyrus medial segment (mild atrophy on the left and mild-to-moderate atrophy on the right), supplementary motor cortex (mild atrophy both left and right), middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), gyrus rectus (mild atrophy on the left and normal on the right), lateral orbital gyrus (mild atrophy on the left and normal on the right), sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right), frontal pole (normal on the left and mild atrophy on the right) and medial frontal cortex (mild atrophy on the left)
- mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: frontal operculum (mild atrophy both left and right), parietal operculum (mild atrophy on the left and normal-to-mild atrophy on the right) and central operculum (normal on the left and mild atrophy on the right)
- mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy both left and right), transverse temporal gyrus (mild atrophy on the right), planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right)
For additional Regions of Interest:
- mild-to-moderate atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) and moderate atrophy of the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) demonstrates a healthy morphology without signs of atrophy
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) maintains a normal appearance with no observable atrophic features
|
PNFA
|
ADNI_057_S_6869_MR_Accelerated_Sagittal_IR-FSPGR__br_raw_20230306171828752_181_S1200890_I1673575_dupl_2
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild-to-moderate atrophy of the left amygdala and moderate atrophy of the right amygdala
- mild-to-moderate bilateral atrophy of the thalamus
- moderate bilateral atrophy of the caudate
- moderate bilateral atrophy of the putamen
- moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- mild-to-moderate bilateral atrophy of the pallidum
- mild atrophy of the left hippocampus, moderate atrophy of the right hippocampus
For the ventricles:
- mild-to-moderate enlargement of the external csf
- severe bilateral enlargement of the inf. lateral ventricle
- mild-to-moderate enlargement of the 4th ventricle
- severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- moderate enlargement of the 3rd ventricle
For the cerebral cortex:
- mild-to-moderate atrophy of the right occipital lobe; normal-to-mild atrophy of the left occipital lobe; focal volume loss observed in the following subregions: calcarine cortex (mild atrophy on the left and mild-to-moderate atrophy on the right), cuneus (normal on the left and mild atrophy on the right) and middle occipital gyrus (normal on the left and mild atrophy on the right)
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (normal-to-mild atrophy on the left and mild atrophy on the right)
- no clear atrophic alterations are visible in the parietal lobe
- no observable atrophic changes in the frontal lobe
- mild atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: planum temporale (mild-to-moderate atrophy both left and right), middle temporal gyrus (mild atrophy both left and right) and fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right)
- limbic cortex appears preserved, with no observable tissue loss
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) appears preserved, with no observable tissue loss
- mild atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); normal-to-mild atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- no observable atrophic changes in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild-to-moderate atrophy of the right medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus); normal-to-mild atrophy of the left medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
AD
|
FTLD_203666905_03506_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450860_dupl_14
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild-to-moderate enlargement of the 4th ventricle
- severe enlargement of the 3rd ventricle
- moderate enlargement of the left inf. lateral ventricle and severe enlargement of the right inf. lateral ventricle
- severe bilateral enlargement of the lateral ventricle
- no findings suggestive of enlargement are seen in the external csf
For the subcortical structures:
- caudate maintains a normal appearance with no observable atrophic features
- moderate bilateral atrophy of the pallidum
- mild-to-moderate bilateral atrophy of the putamen
- mild atrophy of the right hippocampus
- mild atrophy of the right amygdala; the left amygdala is normal
- mild-to-moderate atrophy of the left accumbens and moderate atrophy of the right accumbens
- mild-to-moderate atrophy of the left thalamus and moderate atrophy of the right thalamus
For the cerebral cortex:
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy both left and right) and central operculum (normal on the left and mild atrophy on the right)
- mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: orbital inf. frontal gyrus (mild atrophy both left and right), posterior orbital gyrus (mild-to-moderate atrophy on the left and normal on the right), precentral gyrus (mild-to-moderate atrophy on the left and normal on the right), gyrus rectus (normal on the left and mild atrophy on the right), medial frontal cortex (normal on the left and mild atrophy on the right) and precentral gyrus medial segment (mild atrophy on the left and normal on the right)
- limbic cortex appears within normal limits without apparent atrophy
- temporal lobe maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the occipital lobe
For additional Regions of Interest:
- mild atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) is normal
- mild bilateral atrophy of the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
PNFA
|
FTLD_203552830_03035_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177911_dupl_1
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild atrophy of the right thalamus; the left thalamus is normal
- mild-to-moderate atrophy of the left hippocampus, moderate-to-severe atrophy of the right hippocampus
- severe bilateral atrophy of the amygdala
- moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- mild-to-moderate atrophy of the right caudate; normal-to-mild atrophy of the left caudate
- mild atrophy of the left pallidum and mild-to-moderate atrophy of the right pallidum
- mild atrophy of the left putamen and moderate atrophy of the right putamen
For the ventricles:
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
- mild-to-moderate enlargement of the external csf
- mild-to-moderate bilateral enlargement of the lateral ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- mild-to-moderate enlargement of the 3rd ventricle
For the cerebral cortex:
- no evident atrophy or tissue thinning seen in the occipital lobe
- no findings suggestive of atrophy are seen in the frontal lobe
- mild atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), anterior insula (mild atrophy on the left and moderate atrophy on the right) and parietal operculum (mild atrophy on the left and normal on the right)
- parietal lobe appears preserved, with no observable tissue loss
- mild atrophy of the left limbic cortex and moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (mild-to-moderate atrophy both left and right), parahippocampal gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), posterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and anterior cingulate gyrus (normal on the left and mild atrophy on the right)
- moderate-to-severe atrophy of the left temporal lobe and severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), temporal pole (moderate atrophy both left and right), fusiform gyrus (mild-to-moderate atrophy on the left and moderate atrophy on the right), sup. temporal gyrus (mild-to-moderate atrophy both left and right), inf. temporal gyrus (normal-to-mild atrophy on the left and moderate atrophy on the right) and planum polare (normal on the left and mild-to-moderate atrophy on the right)
For additional Regions of Interest:
- no observable atrophic changes in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- mild-to-moderate atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)); the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) is normal
- moderate atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) and severe atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- mild-to-moderate bilateral atrophy of the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
SV
|
FTLD_203175368_01867_MR_Sagittal_MP-Rage_br_raw_20230209093418458_I10183210_dupl_9
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- moderate atrophy of the left putamen; normal-to-mild atrophy of the right putamen
- mild atrophy of the left thalamus; the right thalamus is normal
- mild atrophy of the left hippocampus
- mild atrophy of the left pallidum; the right pallidum is normal
- severe atrophy of the left amygdala and moderate atrophy of the right amygdala
- moderate atrophy of the left caudate; the right caudate is normal
- moderate atrophy of the left accumbens and mild atrophy of the right accumbens
For the cerebral cortex:
- moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy on the left and mild atrophy on the right), entorhinal area (mild atrophy both left and right), posterior cingulate gyrus (mild atrophy on the left) and parahippocampal gyrus (mild atrophy on the left and normal on the right)
- mild-to-moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and normal-to-mild atrophy on the right), fusiform gyrus (mild atrophy both left and right) and middle temporal gyrus (mild atrophy on the left and normal on the right)
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (severe atrophy on the left and moderate atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), central operculum (mild atrophy on the left) and posterior insula (mild atrophy on the left and normal on the right)
- no evident atrophy or tissue thinning seen in the occipital lobe
- severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (moderate atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus medial segment (mild-to-moderate atrophy both left and right), frontal pole (mild-to-moderate atrophy both left and right), triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), middle frontal gyrus (moderate atrophy on the left and normal on the right), sup. frontal gyrus (mild atrophy both left and right), orbital inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), lateral orbital gyrus (mild-to-moderate atrophy on the left), opercular inf. frontal gyrus (mild atrophy on the left and normal on the right) and medial frontal cortex (mild atrophy on the left and normal on the right)
For the ventricles:
- mild-to-moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- moderate enlargement of the external csf
- moderate enlargement of the 3rd ventricle
- mild bilateral enlargement of the lateral ventricle
- mild enlargement of the 4th ventricle
For additional Regions of Interest:
- moderate atrophy of the left fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula); the right fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) is normal
- severe atrophy of the left salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) and moderate atrophy of the right salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- moderate atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala); the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) is normal
- no findings suggestive of atrophy are seen in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
SV
|
FTLD_203142083_03384_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450647_dupl_11
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the caudate
- putamen maintains a normal appearance with no observable atrophic features
- no observable atrophic changes in the thalamus
- mild atrophy of the left hippocampus
- no observable atrophic changes in the pallidum
- moderate atrophy of the left amygdala; the right amygdala is normal
- no evident atrophy or tissue thinning seen in the accumbens
For the ventricles:
- mild enlargement of the 3rd ventricle
- external csf maintains a typical volume without observable enlargement
- severe enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- the lateral ventricle shows no notable changes suggestive of enlargement
- no evident size increase noted in the 4th ventricle
For the cerebral cortex:
- the parietal lobe shows no notable changes suggestive of atrophy
- occipital lobe appears preserved, with no observable tissue loss
- insular cortex appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the frontal lobe
- no clear atrophic alterations are visible in the limbic cortex
- moderate atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), temporal pole (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and fusiform gyrus (mild atrophy on the left)
For additional Regions of Interest:
- fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula) appears within normal limits without apparent atrophy
- no clear atrophic alterations are visible in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- moderate-to-severe atrophy of the left medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala) and mild atrophy of the right medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) appears within normal limits without apparent atrophy
|
SV
|
FTLD_203237221_01123_MR_Sagittal_MP-Rage_br_raw_20230206162139987_I10181612
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild bilateral atrophy of the occipital lobe; focal volume loss observed in the following subregions: lingual gyrus (mild atrophy both left and right), occipital fusiform gyrus (mild atrophy on the right) and middle occipital gyrus (mild atrophy on the left)
- no clear atrophic alterations are visible in the temporal lobe
- parietal lobe maintains a normal appearance with no observable atrophic features
- no observable atrophic changes in the insular cortex
- frontal lobe appears preserved, with no observable tissue loss
- limbic cortex demonstrates a healthy morphology without signs of atrophy
For the ventricles:
- the inf. lateral ventricle shows no notable changes suggestive of enlargement
- 4th ventricle maintains a typical volume without observable enlargement
- 3rd ventricle maintains its expected proportions without signs of enlargement
- lateral ventricle maintains a typical volume without observable enlargement
- no observable enlargement of the external csf
For the subcortical structures:
- no clear atrophic alterations are visible in the hippocampus
- no appreciable degenerative or atrophic changes observed in the thalamus
- putamen demonstrates a healthy morphology without signs of atrophy
- caudate demonstrates a healthy morphology without signs of atrophy
- the amygdala shows no notable changes suggestive of atrophy
- pallidum appears within normal limits without apparent atrophy
- no observable atrophic changes in the accumbens
For additional Regions of Interest:
- no observable atrophic changes in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- no observable atrophic changes in the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca))
- no clear atrophic alterations are visible in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- no observable atrophic changes in the medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus)
|
CN
|
FTLD_203788451_02158_MR_Sagittal_MP-Rage_br_raw_20230206180137317_I10182334
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no clear atrophic alterations are visible in the accumbens
- no clear atrophic alterations are visible in the hippocampus
- no clear atrophic alterations are visible in the putamen
- the pallidum shows no notable changes suggestive of atrophy
- caudate demonstrates a healthy morphology without signs of atrophy
- no appreciable degenerative or atrophic changes observed in the amygdala
- the thalamus shows no notable changes suggestive of atrophy
For the ventricles:
- 4th ventricle maintains its expected proportions without signs of enlargement
- the 3rd ventricle shows no notable changes suggestive of enlargement
- no clear enlargement or abnormal growth seen in the inf. lateral ventricle
- no appreciable enlargement noted in the external csf
- no clear enlargement or abnormal growth seen in the lateral ventricle
For the cerebral cortex:
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- the temporal lobe shows no notable changes suggestive of atrophy
- the frontal lobe shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- insular cortex appears within normal limits without apparent atrophy
- limbic cortex demonstrates a healthy morphology without signs of atrophy
For additional Regions of Interest:
- no appreciable degenerative or atrophic changes observed in the fronto-opercular and motor speech-control network (broca's area, frontal operculum, precentral gyrus, supplementary motor cortex, anterior insula)
- the salience and ventromedial prefrontal (vmpfc) fronto-insular complex (anterior insula (ains), anterior cingulate gyrus (acgg), orbitofrontal cortex (ofc), gyrus rectus (gre), subcallosal area (sca)) shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the medial temporal lobe and limbic-paralimbic memory complex (temporal pole, inferior temporal gyrus, fusiform gyrus, parahippocampal gyrus, amygdala)
- medial temporal lobe-default mode network (mtl-dmn) memory complex (hippocampus, entorhinal cortex, parahippocampal gyrus, precuneus, posterior cingulate, angular gyrus) appears within normal limits without apparent atrophy
|
CN
|
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