Recently, researchers have discovered the first type of gene mutation that helps fight Alzheimer's disease. People who carry this type of gene mutation have a greatly reduced risk of developing dementia symptoms after entering old age. Researchers conducted health surveys and gene sequencing on 1795 study subjects. Later, it was discovered that the gene that affects Alzheimer's disease, the amyloid precursor protein gene, has different types of mutations, and some people who carry one of these types of mutations are relatively less likely to develop Alzheimer's disease. The researchers explained that Alzheimer's disease The cause of the disease is the accumulation of beta-amyloid protein in the brain. This is caused by beta-amyloid precursor protein lyase 1 cutting large pieces of protein into small pieces. This mutation in the amyloid precursor protein gene Type can limit the function of beta amyloid precursor protein lyase 1, thereby reducing the risk of Alzheimer's disease.
Studies have found that people with active beta-amyloid precursor protein lyase 1 have a greatly increased proportion of people with Alzheimer's disease can support the researchers' conclusion.