<s>
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
(	O
WCG	O
)	O
is	O
an	O
effort	O
to	O
create	O
the	O
world	O
's	O
largest	O
volunteer	B-Operating_System
computing	I-Operating_System
platform	O
to	O
tackle	O
scientific	O
research	O
that	O
benefits	O
humanity	O
.	O
</s>
<s>
Launched	O
on	O
November	O
16	O
,	O
2004	O
,	O
with	O
proprietary	O
Grid	B-Operating_System
MP	I-Operating_System
client	O
from	O
United	B-Operating_System
Devices	I-Operating_System
and	O
adding	O
support	O
for	O
Berkeley	B-Operating_System
Open	I-Operating_System
Infrastructure	I-Operating_System
for	I-Operating_System
Network	I-Operating_System
Computing	I-Operating_System
(	O
BOINC	B-Operating_System
)	O
in	O
2005	O
,	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
eventually	O
discontinued	O
the	O
Grid	B-Operating_System
MP	I-Operating_System
client	O
and	O
consolidated	O
on	O
the	O
BOINC	B-Operating_System
platform	O
in	O
2008	O
.	O
</s>
<s>
In	O
September	O
2021	O
,	O
it	O
was	O
announced	O
that	O
IBM	O
transferred	O
ownership	O
to	O
the	O
Krembil	O
Research	O
Institute	O
of	O
University	O
Health	O
Network	O
in	O
Toronto	O
,	O
Ontario	B-Architecture
.	O
</s>
<s>
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
utilizes	O
unused	O
processing	O
power	O
of	O
consumer	O
devices	O
(	O
PCs	O
,	O
Laptops	O
,	O
Android	B-Application
Smartphones	O
,	O
etc	O
.	O
)	O
</s>
<s>
These	O
include	O
an	O
OpenZika	O
project	O
paper	O
on	O
the	O
discovery	O
of	O
a	O
compound	O
(	O
FAM	O
3	O
)	O
that	O
inhibits	O
the	O
NS3	O
Helicase	O
protein	O
of	O
the	O
Zika	O
virus	O
,	O
thus	O
reducing	O
viral	O
replication	O
by	O
up	O
to	O
86%	O
;	O
a	O
FightAIDS	B-Operating_System
@home	I-Operating_System
paper	O
on	O
the	O
discovery	O
of	O
new	O
vulnerabilities	O
on	O
the	O
HIV-1	O
Capsid	O
protein	O
which	O
may	O
allow	O
for	O
a	O
new	O
drug	O
target	O
;	O
a	O
FightAIDS	B-Operating_System
@home	I-Operating_System
paper	O
on	O
new	O
computational	O
drug	O
discovery	O
techniques	O
for	O
more	O
refined	O
and	O
accurate	O
results	O
.	O
</s>
<s>
Based	O
on	O
the	O
success	O
of	O
the	O
Smallpox	O
study	O
,	O
IBM	O
announced	O
the	O
creation	O
of	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
on	O
November	O
16	O
,	O
2004	O
,	O
with	O
the	O
goal	O
of	O
creating	O
a	O
technical	O
environment	O
where	O
other	O
humanitarian	O
research	O
could	O
be	O
processed	O
.	O
</s>
<s>
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
initially	O
only	O
supported	O
Windows	O
,	O
using	O
the	O
proprietary	O
Grid	B-Operating_System
MP	I-Operating_System
software	O
from	O
United	B-Operating_System
Devices	I-Operating_System
which	O
powered	O
the	O
grid.org	O
distributed	B-Operating_System
computing	I-Operating_System
projects	I-Operating_System
.	O
</s>
<s>
Demand	O
for	O
Linux	B-Application
support	O
led	O
to	O
the	O
addition	O
in	O
November	O
2005	O
of	O
open	O
source	O
Berkeley	B-Operating_System
Open	I-Operating_System
Infrastructure	I-Operating_System
for	I-Operating_System
Network	I-Operating_System
Computing	I-Operating_System
(	O
BOINC	B-Operating_System
)	O
software	O
which	O
powers	O
projects	O
such	O
as	O
SETI	B-Application
@home	I-Application
and	O
Climateprediction	B-Operating_System
.	O
</s>
<s>
Mac	B-Application
OS	I-Application
and	O
Linux	B-Application
support	O
was	O
added	O
since	O
the	O
introduction	O
of	O
BOINC	B-Operating_System
.	O
</s>
<s>
In	O
2007	O
,	O
the	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
migrated	O
from	O
Grid	B-Operating_System
MP	I-Operating_System
to	O
BOINC	B-Operating_System
for	O
all	O
of	O
its	O
supported	O
platforms	O
.	O
</s>
<s>
In	O
September	O
2021	O
,	O
IBM	O
announced	O
that	O
it	O
had	O
transferred	O
ownership	O
of	O
the	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
to	O
the	O
Krembil	O
Research	O
Institute	O
.	O
</s>
<s>
As	O
of	O
September	O
21	O
,	O
2021	O
,	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
had	O
over	O
33,000	O
active	O
user	O
accounts	O
,	O
with	O
over	O
154,000	O
active	O
devices	O
.	O
</s>
<s>
The	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
software	O
uses	O
the	O
unused	O
computing	O
time	O
of	O
Internet-connected	O
devices	O
to	O
perform	O
research	O
calculations	O
.	O
</s>
<s>
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
offers	O
multiple	O
humanitarian	O
projects	O
under	O
a	O
single	O
umbrella	O
.	O
</s>
<s>
The	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
software	O
increases	O
CPU	B-Device
usage	O
by	O
consuming	O
unused	O
processing	O
time	O
;	O
in	O
the	O
late	O
1990s	O
and	O
early	O
2000s	O
,	O
such	O
calculations	O
were	O
meant	O
to	O
reduce	O
"	O
wasted	O
"	O
CPU	B-Device
cycles	O
.	O
</s>
<s>
With	O
modern	O
CPUs	B-Device
,	O
where	O
dynamic	B-General_Concept
frequency	I-General_Concept
scaling	I-General_Concept
is	O
prevalent	O
,	O
increased	O
usage	O
makes	O
the	O
processor	O
run	O
at	O
higher	O
frequency	O
,	O
increasing	O
power	O
usage	O
and	O
heating	O
counter	O
to	O
power	O
management	O
.	O
</s>
<s>
The	O
BOINC	B-Operating_System
client	O
avoids	O
slowing	O
the	O
computer	O
by	O
using	O
a	O
variety	O
of	O
limits	O
that	O
suspend	O
computation	O
when	O
there	O
are	O
insufficient	O
free	O
resources	O
.	O
</s>
<s>
Unlike	O
other	O
BOINC	B-Operating_System
projects	O
,	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
set	O
the	O
BOINC	B-Operating_System
defaults	O
conservatively	O
,	O
making	O
the	O
chances	O
of	O
computer	O
damage	O
extremely	O
small	O
.	O
</s>
<s>
The	O
default	O
CPU	B-Device
throttle	O
is	O
60%	O
.	O
</s>
<s>
An	O
add-on	O
program	O
for	O
Windows	B-Application
computers	I-Application
–	O
–	O
can	O
solve	O
the	O
problem	O
of	O
overheating	O
by	O
directly	O
limiting	O
the	O
BOINC	B-Operating_System
project	O
's	O
use	O
of	O
the	O
host	O
computer	O
.	O
</s>
<s>
It	O
does	O
this	O
by	O
measuring	O
the	O
CPU	B-Device
and/or	O
the	O
GPU	B-Architecture
temperature	O
and	O
adjusts	O
the	O
run	O
time	O
accordingly	O
.	O
</s>
<s>
Upon	O
completing	O
a	O
workunit	O
,	O
the	O
BOINC	B-Operating_System
client	O
will	O
request	O
the	O
number	O
of	O
points	O
it	O
thinks	O
it	O
deserves	O
based	O
on	O
software	O
benchmarks	O
(	O
see	O
BOINC	B-Operating_System
Credit	O
System	O
#Cobblestones	O
)	O
.	O
</s>
<s>
Since	O
multiple	O
computers	O
process	O
the	O
same	O
workunit	O
to	O
ensure	O
accuracy	O
,	O
the	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
servers	O
can	O
look	O
at	O
the	O
points	O
claimed	O
by	O
each	O
of	O
those	O
computers	O
.	O
</s>
<s>
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
recognizes	O
companies	O
and	O
organizations	O
as	O
partners	O
if	O
they	O
promote	O
WCG	O
within	O
their	O
company	O
or	O
organization	O
.	O
</s>
<s>
Also	O
,	O
as	O
part	O
of	O
its	O
commitment	O
to	O
improving	O
human	O
health	O
and	O
welfare	O
,	O
the	O
results	O
of	O
all	O
computations	O
completed	O
on	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
are	O
released	O
into	O
the	O
public	O
domain	O
and	O
made	O
available	O
to	O
the	O
scientific	O
community	O
.	O
</s>
<s>
Since	O
its	O
launch	O
,	O
more	O
than	O
thirty	O
projects	O
have	O
run	O
in	O
the	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
.	O
</s>
<s>
In	O
February	O
2014	O
,	O
the	O
Help	B-Operating_System
Fight	I-Operating_System
Childhood	I-Operating_System
Cancer	I-Operating_System
project	O
scientists	O
announced	O
the	O
discovery	O
of	O
7	O
compounds	O
that	O
destroy	O
neuroblastoma	O
cancer	O
cells	O
without	O
any	O
apparent	O
side	O
effects	O
.	O
</s>
<s>
As	O
of	O
July	O
2012	O
,	O
the	O
Human	B-Operating_System
Proteome	I-Operating_System
Folding	I-Operating_System
Project	I-Operating_System
has	O
published	O
several	O
papers	O
using	O
data	O
from	O
WCG	O
.	O
</s>
<s>
The	O
Discovering	B-Operating_System
Dengue	I-Operating_System
Drugs	I-Operating_System
-	I-Operating_System
Together	I-Operating_System
project	O
scientists	O
reported	O
the	O
discovery	O
of	O
several	O
new	O
Dengue	O
protease	O
inhibitors	O
,	O
most	O
of	O
which	O
also	O
inhibit	O
the	O
West	O
Nile	O
virus	O
protease	O
.	O
</s>
<s>
In	O
June	O
2013	O
,	O
the	O
Clean	B-Operating_System
Energy	I-Operating_System
Project	I-Operating_System
published	O
a	O
database	O
of	O
over	O
2.3	O
million	O
organic	O
molecules	O
which	O
have	O
had	O
their	O
properties	O
characterized	O
.	O
</s>
<s>
In	O
February	O
2010	O
,	O
the	O
FightAIDS	B-Operating_System
@Home	I-Operating_System
project	O
scientists	O
announced	O
that	O
they	O
have	O
found	O
two	O
compounds	O
which	O
make	O
a	O
potentially	O
new	O
class	O
of	O
AIDS-fighting	O
drugs	O
possible	O
.	O
</s>
<s>
By	O
running	O
simulations	O
on	O
WCG	O
,	O
the	O
scientists	O
discovered	O
that	O
certain	O
kinds	O
of	O
natural	O
vibrations	O
called	O
phonons	B-Language
,	O
under	O
specific	O
conditions	O
,	O
can	O
lead	O
to	O
more	O
than	O
300%	O
increased	O
flow	O
of	O
water	O
through	O
the	O
nanotubes	O
,	O
compared	O
to	O
previous	O
theoretical	O
predictions	O
.	O
</s>
<s>
In	O
March	O
2019	O
,	O
FightAIDS	B-Operating_System
@Home	I-Operating_System
researchers	O
published	O
a	O
paper	O
describing	O
a	O
"	O
Novel	O
Intersubunit	O
Interaction	O
Critical	O
for	O
HIV-1	O
Core	O
Assembly	O
"	O
that	O
"	O
defines	O
a	O
Potentially	O
Targetable	O
Inhibitor	O
Binding	O
Pocket	O
"	O
.	O
</s>
<s>
Using	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
,	O
more	O
than	O
1.6	O
million	O
compounds	O
were	O
used	O
to	O
target	O
20	O
conformations	O
of	O
this	O
pocket	O
.	O
</s>
<s>
WCG	O
will	O
partner	O
with	O
Scripps	O
Research	O
,	O
with	O
whom	O
it	O
has	O
partnered	O
in	O
the	O
past	O
,	O
notably	O
in	O
FightAIDS	B-Operating_System
@Home	I-Operating_System
projects	O
.	O
</s>
<s>
The	O
project	O
runs	O
on	O
CPUs	B-Device
and	O
GPUs	B-Architecture
and	O
will	O
also	O
serve	O
to	O
create	O
a	O
"	O
fast-response	O
,	O
open	O
source	O
tool	O
that	O
will	O
help	O
all	O
scientists	O
quickly	O
search	O
for	O
treatments	O
for	O
future	O
pandemics.	O
"	O
</s>
<s>
FightAIDS	B-Operating_System
@Home	I-Operating_System
Phase	O
2	O
(	O
launched	O
September	O
30	O
,	O
2015	O
)	O
is	O
looking	O
more	O
closely	O
at	O
the	O
results	O
of	O
Phase	O
1	O
.	O
</s>
<s>
The	O
project	O
has	O
two	O
goals	O
in	O
the	O
early	O
experiments	O
;	O
the	O
simulation	O
architecture	O
is	O
functioning	O
correctly	O
and	O
giving	O
reliable	O
results	O
,	O
and	O
using	O
BEDAM	O
and	O
AutoDock	B-Application
together	O
provides	O
better	O
results	O
than	O
using	O
just	O
BEDAM	O
or	O
AutoDock	B-Application
.	O
</s>
<s>
Launched	O
in	O
January	O
2017	O
,	O
the	O
Smash	B-Operating_System
Childhood	I-Operating_System
Cancer	I-Operating_System
project	O
builds	O
on	O
the	O
work	O
from	O
the	O
Help	B-Operating_System
Fight	I-Operating_System
Childhood	I-Operating_System
Cancer	I-Operating_System
project	O
by	O
looking	O
for	O
drug	O
candidates	O
targeting	O
additional	O
childhood	O
cancers	O
.	O
</s>
<s>
Upon	O
Dr.	O
Akira	O
Nakagawara	O
's	O
retirement	O
in	O
March	O
2020	O
,	O
the	O
principal	O
investigator	O
changed	O
to	O
Dr.	O
Godfrey	O
Chan	O
,	O
who	O
was	O
one	O
of	O
the	O
original	O
members	O
of	O
the	O
Smash	B-Operating_System
Childhood	I-Operating_System
Cancer	I-Operating_System
team	O
.	O
</s>
<s>
The	O
Africa	O
Rainfall	O
Project	O
(	O
launched	O
October	O
2019	O
)	O
will	O
use	O
the	O
computing	O
power	O
of	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
,	O
data	O
from	O
The	O
Weather	O
Company	O
,	O
and	O
other	O
data	O
to	O
improve	O
rainfall	O
modelling	O
,	O
which	O
can	O
help	O
farmers	O
in	O
sub-Saharan	O
Africa	O
successfully	O
raise	O
their	O
crops	O
.	O
</s>
<s>
The	O
first	O
project	O
launched	O
on	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
was	O
the	O
Human	B-Operating_System
Proteome	I-Operating_System
Folding	I-Operating_System
Project	I-Operating_System
,	O
or	O
HPF1	O
,	O
which	O
aims	O
to	O
predict	O
the	O
structure	O
of	O
human	O
proteins	O
.	O
</s>
<s>
This	O
project	O
was	O
unique	O
in	O
that	O
computation	O
was	O
done	O
in	O
tandem	O
with	O
the	O
grid.org	O
distributed	B-Operating_System
computing	I-Operating_System
project	I-Operating_System
.	O
</s>
<s>
Human	O
Proteome	O
Folding	O
-	O
Phase	O
2	O
(	O
HPF2	O
)	O
(	O
launched	O
June	O
23	O
,	O
2006	O
)	O
was	O
the	O
third	O
project	O
to	O
run	O
on	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
,	O
and	O
completed	O
in	O
2013	O
.	O
</s>
<s>
Help	O
Cure	O
Muscular	O
Dystrophy	O
is	O
run	O
by	O
Décrypthon	B-Operating_System
,	O
a	O
collaboration	O
between	O
French	O
Muscular	O
Dystrophy	O
Association	O
,	O
French	B-Application
National	I-Application
Center	I-Application
for	I-Application
Scientific	I-Application
Research	I-Application
and	O
IBM	O
.	O
</s>
<s>
This	O
project	O
was	O
available	O
only	O
to	O
agents	O
running	O
the	O
Grid	B-Operating_System
MP	I-Operating_System
client	O
,	O
making	O
it	O
unavailable	O
to	O
users	O
running	O
BOINC	B-Operating_System
.	O
</s>
<s>
Discovering	B-Operating_System
Dengue	I-Operating_System
Drugs	I-Operating_System
–	I-Operating_System
Together	I-Operating_System
was	O
sponsored	O
by	O
scientists	O
at	O
the	O
University	O
of	O
Texas	O
and	O
the	O
University	O
of	O
Chicago	O
and	O
will	O
run	O
in	O
two	O
phases	O
.	O
</s>
<s>
Phase	O
1	O
,	O
launched	O
August	O
21	O
,	O
2007	O
,	O
used	O
AutoDock	B-Application
2007	O
(	O
the	O
same	O
software	O
used	O
for	O
FightAIDS	B-Operating_System
@Home	I-Operating_System
)	O
to	O
test	O
potential	O
antiviral	O
drugs	O
(	O
through	O
NS3	O
protease	O
inhibition	O
)	O
against	O
viruses	O
from	O
the	O
family	O
flaviviridae	O
and	O
completed	O
on	O
August	O
11	O
,	O
2009	O
.	O
</s>
<s>
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
's	O
tremendous	O
computing	O
power	O
was	O
used	O
to	O
understand	O
and	O
reduce	O
the	O
uncertainty	O
with	O
which	O
climate	O
processes	O
were	O
simulated	O
over	O
Africa	O
.	O
</s>
<s>
Help	O
Conquer	O
Cancer	O
project	O
(	O
launched	O
November	O
1	O
,	O
2007	O
)	O
is	O
sponsored	O
by	O
the	O
Ontario	B-Architecture
Cancer	O
Institute	O
(	O
OCI	O
)	O
,	O
Princess	O
Margaret	O
Hospital	O
and	O
University	O
Health	O
Network	O
of	O
Toronto	O
,	O
Canada	O
.	O
</s>
<s>
The	O
HCC	O
project	O
was	O
the	O
first	O
WCG	O
project	O
benefiting	O
from	O
graphics	B-Architecture
processing	I-Architecture
units	I-Architecture
(	O
GPU	B-Architecture
)	O
s	O
which	O
helped	O
finish	O
it	O
a	O
lot	O
earlier	O
than	O
initially	O
projected	O
due	O
to	O
the	O
massive	O
power	O
of	O
GPUs	B-Architecture
.	O
</s>
<s>
On	O
April	O
13	O
,	O
2010	O
,	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
officially	O
announced	O
that	O
the	O
Nutritious	O
Rice	O
for	O
the	O
World	O
project	O
finished	O
on	O
April	O
6	O
,	O
2010	O
.	O
</s>
<s>
The	O
Clean	B-Operating_System
Energy	I-Operating_System
project	I-Operating_System
is	O
sponsored	O
by	O
the	O
scientists	O
of	O
Harvard	O
University	O
's	O
Department	O
of	O
Chemistry	O
and	O
Chemical	O
Biology	O
.	O
</s>
<s>
The	O
mission	O
of	O
the	O
Clean	B-Operating_System
Energy	I-Operating_System
Project	I-Operating_System
is	O
to	O
find	O
new	O
materials	O
for	O
the	O
next	O
generation	O
of	O
solar	O
cells	O
and	O
later	O
,	O
energy	O
storage	O
devices	O
.	O
</s>
<s>
By	O
harnessing	O
the	O
computing	O
power	O
of	O
the	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
,	O
researchers	O
were	O
able	O
to	O
calculate	O
the	O
electronic	O
properties	O
of	O
tens	O
of	O
thousands	O
of	O
organic	O
materials	O
–	O
many	O
more	O
than	O
could	O
ever	O
be	O
tested	O
in	O
a	O
lab	O
–	O
and	O
determine	O
which	O
candidates	O
are	O
most	O
promising	O
for	O
developing	O
affordable	O
solar	O
energy	O
technology	O
.	O
</s>
<s>
Further	O
calculations	O
about	O
optical	O
,	O
electronic	O
and	O
other	O
physical	O
properties	O
of	O
the	O
candidate	O
materials	O
are	O
being	O
conducted	O
with	O
the	O
Q-Chem	B-Language
quantum	O
chemistry	O
software	O
.	O
</s>
<s>
Help	B-Operating_System
Fight	I-Operating_System
Childhood	I-Operating_System
Cancer	I-Operating_System
project	O
(	O
launched	O
March	O
13	O
,	O
2009	O
)	O
is	O
sponsored	O
by	O
the	O
scientists	O
at	O
Chiba	O
Cancer	O
Center	O
Research	O
Institute	O
and	O
Chiba	O
University	O
.	O
</s>
<s>
The	O
mission	O
of	O
the	O
Help	B-Operating_System
Fight	I-Operating_System
Childhood	I-Operating_System
Cancer	I-Operating_System
project	O
is	O
to	O
find	O
drugs	O
that	O
can	O
disable	O
three	O
particular	O
proteins	O
associated	O
with	O
neuroblastoma	O
,	O
one	O
of	O
the	O
most	O
frequently	O
occurring	O
solid	O
tumors	O
in	O
children	O
.	O
</s>
<s>
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
and	O
researchers	O
supported	O
by	O
Decrypthon	B-Operating_System
,	O
a	O
partnership	O
between	O
AFM	O
(	O
French	O
Muscular	O
Dystrophy	O
Association	O
)	O
,	O
CNRS	B-Application
(	O
French	B-Application
National	I-Application
Center	I-Application
for	I-Application
Scientific	I-Application
Research	I-Application
)	O
,	O
Universite	O
Pierre	O
et	O
Marie	O
Curie	O
,	O
and	O
IBM	O
were	O
investigating	O
protein	O
–	O
protein	O
interactions	O
for	O
more	O
than	O
2,200	O
proteins	O
whose	O
structures	O
are	O
known	O
,	O
with	O
particular	O
focus	O
on	O
those	O
proteins	O
that	O
play	O
a	O
role	O
in	O
neuromuscular	O
diseases	O
.	O
</s>
<s>
Phase	O
2	O
ran	O
on	O
the	O
BOINC	B-Operating_System
platform	O
.	O
</s>
<s>
Discovering	B-Operating_System
Dengue	I-Operating_System
Drugs	I-Operating_System
–	I-Operating_System
Together	I-Operating_System
–	O
Phase	O
2	O
(	O
launched	O
February	O
17	O
,	O
2010	O
)	O
is	O
sponsored	O
by	O
The	O
University	O
of	O
Texas	O
Medical	O
Branch	O
(	O
UTMB	O
)	O
in	O
Galveston	O
,	O
Texas	O
,	O
United	O
States	O
and	O
the	O
University	O
of	O
Chicago	O
in	O
Illinois	O
,	O
USA	O
.	O
</s>
<s>
The	O
extensive	O
computing	O
power	O
of	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
will	O
be	O
used	O
to	O
complete	O
the	O
structure-based	O
drug	O
discovery	O
calculations	O
required	O
to	O
identify	O
these	O
drug	O
candidates	O
.	O
</s>
<s>
The	O
extensive	O
computing	O
power	O
of	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
will	O
be	O
used	O
to	O
perform	O
computer	O
simulations	O
of	O
the	O
interactions	O
between	O
millions	O
of	O
chemical	O
compounds	O
and	O
certain	O
target	O
proteins	O
.	O
</s>
<s>
The	O
computing	O
power	O
of	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
will	O
be	O
used	O
to	O
perform	O
computer	O
simulations	O
of	O
the	O
interactions	O
between	O
millions	O
of	O
chemical	O
compounds	O
and	O
certain	O
target	O
proteins	O
,	O
to	O
predict	O
their	O
ability	O
to	O
eliminate	O
malaria	O
.	O
</s>
<s>
Say	O
No	O
to	O
Schistosoma	O
(	O
launched	O
February	O
22	O
,	O
2012	O
)	O
was	O
the	O
20th	O
research	O
project	O
to	O
be	O
launched	O
on	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
.	O
</s>
<s>
The	O
researchers	O
at	O
Infórium	O
University	O
in	O
Belo	O
Horizonte	O
and	O
FIOCRUZ-Minas	O
,	O
Brazil	O
,	O
ran	O
this	O
project	O
on	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
to	O
perform	O
computer	O
simulations	O
of	O
the	O
interactions	O
between	O
millions	O
of	O
chemical	O
compounds	O
and	O
certain	O
target	O
proteins	O
in	O
the	O
hope	O
of	O
finding	O
effective	O
treatments	O
for	O
schistosomiasis	O
.	O
</s>
<s>
Computing	O
for	O
Sustainable	O
Water	O
was	O
the	O
21st	O
research	O
project	O
to	O
be	O
launched	O
on	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
.	O
</s>
<s>
The	O
researchers	O
at	O
the	O
University	O
of	O
Virginia	O
were	O
running	O
this	O
project	O
on	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
to	O
study	O
the	O
effects	O
of	O
human	O
activity	O
on	O
a	O
large	O
watershed	O
and	O
gain	O
deeper	O
insights	O
into	O
what	O
actions	O
can	O
support	O
the	O
restoration	O
,	O
health	O
and	O
sustainability	O
of	O
this	O
important	O
water	O
resource	O
.	O
</s>
<s>
FightAIDS	B-Operating_System
@Home	I-Operating_System
(	O
launched	O
November	O
19	O
,	O
2005	O
)	O
was	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
's	O
second	O
project	O
and	O
its	O
first	O
to	O
target	O
a	O
single	O
disease	O
.	O
</s>
<s>
Scripps	O
Research	O
Institute	O
published	O
its	O
first	O
peer-reviewed	O
scientific	O
paper	O
about	O
the	O
results	O
of	O
FightAIDS	B-Operating_System
@Home	I-Operating_System
on	O
April	O
21	O
,	O
2007	O
.	O
</s>
<s>
This	O
paper	O
explains	O
that	O
the	O
results	O
up	O
to	O
that	O
point	O
will	O
primarily	O
be	O
used	O
to	O
improve	O
the	O
efficiency	O
of	O
future	O
FightAIDS	B-Operating_System
@Home	I-Operating_System
calculations	O
.	O
</s>
