<s>
Vector	B-Application
NTI	I-Application
was	O
a	O
commercial	B-Application
bioinformatics	O
software	O
package	O
used	O
by	O
many	O
life	O
scientists	O
in	O
the	O
early	O
2000s	O
to	O
work	O
,	O
among	O
other	O
things	O
,	O
with	O
nucleic	O
acids	O
and	O
proteins	O
in	O
silico	O
.	O
</s>
<s>
It	O
allowed	O
researchers	O
to	O
,	O
for	O
example	O
,	O
plan	O
a	O
DNA	O
cloning	B-Application
experiment	O
on	O
the	O
computer	O
before	O
actually	O
performing	O
it	O
in	O
the	O
lab	O
.	O
</s>
<s>
However	O
,	O
in	O
2008	O
it	O
was	O
locked	O
and	O
turned	O
into	O
a	O
commercial	B-Application
software	I-Application
after	O
2008	O
which	O
created	O
problems	O
for	O
locked	O
in	O
users	O
who	O
were	O
forced	O
to	O
buy	O
the	O
software	O
to	O
continue	O
accessing	O
their	O
data	O
on	O
newer	O
computers	O
.	O
</s>
<s>
What	O
was	O
previously	O
a	O
single	O
software	O
package	O
was	O
subsequently	O
split	O
into	O
Vector	B-Application
NTI	I-Application
Express	O
,	O
Advanced	O
,	O
and	O
Express	O
Designer	O
.	O
</s>
<s>
Vector	B-Application
NTI	I-Application
was	O
discontinued	O
by	O
its	O
corporate	O
parent	O
Thermo	O
Fisher	O
at	O
the	O
end	O
of	O
2019	O
and	O
support	O
ceased	O
a	O
year	O
later	O
.	O
</s>
