<s>
An	O
Ussing	B-Algorithm
chamber	I-Algorithm
is	O
an	O
apparatus	O
for	O
measuring	O
epithelial	O
membrane	O
properties	O
.	O
</s>
<s>
The	O
Ussing	B-Algorithm
chamber	I-Algorithm
was	O
invented	O
by	O
the	O
Danish	O
zoologist	O
and	O
physiologist	O
Hans	O
Henriksen	O
Ussing	O
in	O
1946	O
.	O
</s>
<s>
Ussing	B-Algorithm
chambers	I-Algorithm
are	O
used	O
to	O
measure	O
ion	O
transport	O
in	O
native	O
tissue	O
,	O
such	O
as	O
gut	O
mucosa	O
,	O
and	O
in	O
a	O
monolayer	O
of	O
cells	O
grown	O
on	O
permeable	O
supports	O
.	O
</s>
<s>
The	O
Ussing	B-Algorithm
chamber	I-Algorithm
provides	O
a	O
system	O
to	O
measure	O
the	O
transport	O
of	O
ions	O
,	O
nutrients	O
,	O
and	O
drugs	O
across	O
various	O
epithelial	O
tissues	O
,	O
(	O
although	O
can	O
generate	O
false-negative	O
results	O
for	O
lipophilic	O
substances	O
)	O
.	O
</s>
<s>
An	O
Ussing	B-Algorithm
chamber	I-Algorithm
can	O
isolate	O
the	O
apical	O
side	O
from	O
the	O
basolateral	O
side	O
.	O
</s>
<s>
Measuring	O
epithelial	O
ion	O
transport	O
is	O
helped	O
by	O
Ussing	B-Algorithm
chambers	I-Algorithm
.	O
</s>
<s>
The	O
main	O
types	O
of	O
Ussing	B-Algorithm
chamber	I-Algorithm
systems	O
are	O
:	O
</s>
