<s>
Trauma	B-Application
Center	I-Application
:	I-Application
Second	I-Application
Opinion	I-Application
is	O
a	O
simulation	O
video	O
game	O
developed	O
by	O
Atlus	O
for	O
the	B-Operating_System
Wii	I-Operating_System
.	O
</s>
<s>
The	O
second	O
entry	O
in	O
the	O
Trauma	O
Center	O
series	O
,	O
Second	O
Opinion	O
is	O
a	O
remake	O
of	O
the	O
Nintendo	B-Device
DS	I-Device
title	O
Trauma	B-Application
Center	I-Application
:	I-Application
Under	I-Application
the	I-Application
Knife	I-Application
(	O
2005	O
)	O
.	O
</s>
<s>
Gameplay	O
combines	O
surgical	O
simulation	O
with	O
a	O
story	O
told	O
as	O
a	O
visual	O
novel	O
,	O
with	O
operations	O
and	O
control	O
options	O
reworked	O
for	O
the	B-Operating_System
Wii	I-Operating_System
hardware	O
.	O
</s>
<s>
The	O
character	O
Naomi	O
was	O
added	O
to	O
help	O
set	O
the	O
game	O
apart	O
from	O
the	O
Nintendo	B-Device
DS	I-Device
original	O
.	O
</s>
<s>
The	O
game	O
was	O
positively	O
reviewed	O
by	O
journalists	O
,	O
who	O
praised	O
its	O
implementation	O
of	O
the	B-Operating_System
Wii	I-Operating_System
control	O
scheme	O
.	O
</s>
<s>
Trauma	B-Application
Center	I-Application
:	I-Application
Second	I-Application
Opinion	I-Application
is	O
a	O
video	O
game	O
that	O
combines	O
surgical	O
simulation	O
gameplay	O
with	O
storytelling	O
using	O
non-interactive	O
visual	O
novel	O
segments	O
using	O
static	O
scenes	O
,	O
character	O
portraits	O
,	O
text	O
boxes	O
,	O
and	O
rare	O
voice	O
clips	O
during	O
gameplay	O
segments	O
.	O
</s>
<s>
Second	O
Opinion	O
is	O
a	O
remake	O
of	O
Trauma	B-Application
Center	I-Application
:	I-Application
Under	I-Application
the	I-Application
Knife	I-Application
for	O
the	O
Nintendo	B-Device
DS	I-Device
.	O
</s>
<s>
Actions	O
during	O
surgery	O
are	O
guided	O
using	O
the	B-Operating_System
Wii	I-Operating_System
Remote	O
and	O
Nunchuk	O
.	O
</s>
<s>
The	B-Operating_System
Wii	I-Operating_System
Remote	O
is	O
used	O
for	O
many	O
actions	O
including	O
stitching	O
up	O
wounds	O
and	O
using	O
the	O
scalpel	O
,	O
filling	O
the	O
role	O
of	O
the	O
stylus	O
from	O
the	O
Nintendo	B-Device
DS	I-Device
original	O
.	O
</s>
<s>
Players	O
can	O
activate	O
each	O
character	O
's	O
Healing	O
Touch	O
by	O
drawing	O
a	O
star	O
on-screen	O
using	O
the	B-Operating_System
Wii	I-Operating_System
Remote	O
.	O
</s>
<s>
Joining	O
the	O
medical	O
conglomerate	O
Caduceus	B-Application
,	O
Stiles	O
uses	O
his	O
gift	O
to	O
treat	O
those	O
infected	O
with	O
GUILT	O
,	O
aided	O
by	O
his	O
assistant	O
Angela	O
"	O
Angie	O
"	O
Thompson	O
.	O
</s>
<s>
With	O
Blackwell	O
's	O
aid	O
,	O
Caduceus	B-Application
launches	O
a	O
raid	O
on	O
Delphi	O
's	O
headquarters	O
and	O
discovers	O
its	O
founder	O
,	O
Adam	O
.	O
</s>
<s>
Adam	O
is	O
in	O
a	O
vegetative	O
state	O
,	O
hosting	O
all	O
the	O
GUILT	O
strains	O
,	O
and	O
the	O
body	O
is	O
impounded	O
by	O
Caduceus	B-Application
Europe	O
.	O
</s>
<s>
Kimishima	O
remains	O
mostly	O
unaware	O
of	O
the	O
circumstances	O
of	O
Delphi	O
until	O
just	O
before	O
the	O
Caduceus	B-Application
raid	O
,	O
and	O
also	O
places	O
their	O
operation	O
in	O
danger	O
at	O
one	O
point	O
by	O
insisting	O
on	O
operating	O
on	O
a	O
reporter	O
wounded	O
after	O
chasing	O
down	O
a	O
car	O
in	O
which	O
Kimishima	O
and	O
a	O
Delphi	O
operative	O
were	O
passengers	O
.	O
</s>
<s>
Just	O
before	O
their	O
headquarters	O
are	O
discovered	O
by	O
Caduceus	B-Application
,	O
Kimishima	O
escapes	O
with	O
a	O
GUILT	O
sample	O
which	O
she	O
plans	O
to	O
use	O
as	O
a	O
bargaining	O
chip	O
for	O
immunity	O
against	O
all	O
potential	O
charges	O
against	O
her	O
.	O
</s>
<s>
In	O
the	O
new	O
sixth	O
chapter	O
,	O
Stiles	O
is	O
summoned	O
to	O
Caduceus	B-Application
Europe	O
,	O
where	O
Kimishima	O
now	O
works	O
under	O
her	O
real	O
name	O
alongside	O
another	O
doctor	O
called	O
Owen	O
.	O
</s>
<s>
It	O
is	O
revealed	O
that	O
Caduceus	B-Application
Europe	O
have	O
created	O
a	O
new	O
regenerative	O
culture	O
dubbed	O
"	O
Z-Cells	O
"	O
.	O
</s>
<s>
Caduceus	B-Application
Europe	O
is	O
forced	O
to	O
face	O
charges	O
for	O
their	O
actions	O
,	O
Kimishima	O
stays	O
in	O
Europe	O
to	O
pursue	O
her	O
medical	O
career	O
and	O
to	O
compensate	O
for	O
her	O
crimes	O
while	O
working	O
under	O
Delphi	O
,	O
and	O
Stiles	O
spearheads	O
a	O
new	O
drive	O
to	O
eradicate	O
the	O
GUILT	O
pandemic	O
.	O
</s>
<s>
Second	O
Opinion	O
is	O
the	O
second	O
game	O
in	O
the	O
Trauma	O
Center	O
series	O
and	O
the	O
first	O
produced	O
for	O
the	B-Operating_System
Wii	I-Operating_System
.	O
</s>
<s>
Kanada	O
had	O
previously	O
been	O
a	O
designer	O
for	O
multiple	O
Megami	B-Application
Tensei	I-Application
titles	O
,	O
had	O
worked	O
with	O
Hashino	O
since	O
Maken	B-Application
X	I-Application
(	O
1999	O
)	O
,	O
and	O
made	O
his	O
debut	O
as	O
a	O
director	O
with	O
Second	O
Opinion	O
.	O
</s>
<s>
Lead	O
programmer	O
Takaaki	O
Ikeda	O
would	O
work	O
on	O
future	O
Trauma	O
Center	O
titles	O
,	O
while	O
future	O
Persona	B-Application
5	I-Application
art	O
director	O
Masayoshi	O
Suto	O
was	O
lead	O
designer	O
.	O
</s>
<s>
In	O
addition	O
to	O
new	O
tools	O
such	O
as	O
the	O
defibrillator	O
,	O
the	O
original	O
tools	O
such	O
as	O
forceps	O
were	O
carried	O
over	O
and	O
adjusted	O
to	O
fit	O
the	O
new	O
control	O
scheme	O
of	O
the	B-Operating_System
Wii	I-Operating_System
.	O
</s>
<s>
Another	O
composer	O
on	O
the	O
project	O
was	O
Shingo	O
Yasumoto	O
,	O
who	O
had	O
worked	O
on	O
Persona	B-Application
3	I-Application
for	O
Atlus	O
and	O
multiple	O
games	O
for	O
Grasshopper	O
Manufacture	O
.	O
</s>
<s>
While	O
voice	O
acting	O
was	O
still	O
restricted	O
to	O
shout-outs	O
from	O
characters	O
,	O
there	O
were	O
ten	O
times	O
the	O
number	O
compared	O
to	O
the	O
Nintendo	B-Device
DS	I-Device
original	O
,	O
and	O
Stiles	O
was	O
given	O
a	O
voice	O
for	O
the	O
first	O
time	O
.	O
</s>
<s>
The	O
game	O
was	O
announced	O
in	O
May	O
2006	O
at	O
that	O
year	O
's	O
Electronic	O
Entertainment	O
Expo	O
as	O
a	O
launch	O
title	O
for	O
the	B-Operating_System
Wii	I-Operating_System
.	O
</s>
<s>
In	O
Japan	O
,	O
it	O
was	O
originally	O
known	O
under	O
the	O
tentative	O
title	O
Caduceus	B-Application
Neo	O
.	O
</s>
<s>
As	O
with	O
Stile	O
's	O
name	O
in	O
the	O
Nintendo	B-Device
DS	I-Device
version	O
,	O
Kimishima	O
's	O
original	O
surname	O
"	O
Weaver	O
"	O
was	O
written	O
by	O
Atlus	O
USA	O
as	O
a	O
pun	O
on	O
the	O
word	O
"	O
Wii	B-Operating_System
"	O
.	O
</s>
<s>
The	O
game	O
released	O
in	O
North	O
America	O
on	O
November	O
19	O
,	O
2006	O
,	O
releasing	O
concurrently	O
with	O
the	B-Operating_System
Wii	I-Operating_System
console	O
in	O
the	O
region	O
.	O
</s>
<s>
In	O
Japan	O
,	O
the	O
game	O
released	O
on	O
December	O
2	O
of	O
that	O
year	O
alongside	O
the	B-Operating_System
Wii	I-Operating_System
's	O
launch	O
in	O
the	O
region	O
.	O
</s>
<s>
During	O
November	O
2007	O
,	O
Second	O
Opinion	O
was	O
among	O
the	O
better-selling	O
Wii	B-Operating_System
titles	O
for	O
the	O
period	O
,	O
selling	O
around	O
200,000	O
units	O
in	O
North	O
America	O
.	O
</s>
<s>
In	O
January	O
the	O
following	O
year	O
,	O
it	O
was	O
still	O
in	O
the	O
top	O
ten	O
best-selling	O
Wii	B-Operating_System
games	O
of	O
the	O
region	O
.	O
</s>
<s>
Computer	O
and	O
Video	O
Games	O
called	O
it	O
"	O
One	O
of	O
the	O
tightest	O
,	O
and	O
best	O
,	O
games	O
available	O
on	O
Wii.	O
"	O
</s>
<s>
Keza	O
MacDonald	O
,	O
writing	O
for	O
Eurogamer	O
,	O
was	O
highly	O
positive	O
;	O
she	O
said	O
that	O
Second	O
Opinion	O
would	O
help	O
dispel	O
scepticism	O
regarding	O
the	B-Operating_System
Wii	I-Operating_System
's	O
motion	O
control	O
functions	O
.	O
</s>
<s>
Eric	O
Bratcher	O
of	O
GamesRadar	O
regarded	O
the	O
game	O
as	O
the	O
second	O
essential	O
game	O
for	O
Wii	B-Operating_System
owners	O
after	O
The	B-Application
Legend	I-Application
of	I-Application
Zelda	I-Application
:	I-Application
Twilight	I-Application
Princess	I-Application
.	O
</s>
<s>
GameSpys	O
Bryn	O
Williams	O
felt	O
that	O
,	O
despite	O
an	O
occasional	O
lack	O
of	O
polish	O
,	O
the	O
game	O
was	O
an	O
essential	O
purchase	O
for	O
Wii	B-Operating_System
owners	O
.	O
</s>
<s>
Mark	O
Bozon	O
of	O
IGN	O
felt	O
that	O
the	O
game	O
was	O
doing	O
for	O
the	B-Operating_System
Wii	I-Operating_System
what	O
the	O
original	O
did	O
for	O
the	O
Nintendo	B-Device
DS	I-Device
in	O
terms	O
of	O
control	O
innovation	O
.	O
</s>
<s>
Nintendo	O
World	O
Reports	O
Jonathan	O
Metts	O
was	O
also	O
very	O
positive	O
,	O
praising	O
how	O
the	O
game	O
fixed	O
balancing	O
issues	O
present	O
in	O
the	O
Nintendo	B-Device
DS	I-Device
original	O
while	O
adding	O
new	O
and	O
enjoyable	O
content	O
.	O
</s>
<s>
Tom	O
East	O
of	O
Official	O
Nintendo	O
Magazine	O
liked	O
the	O
implementation	O
of	O
the	B-Operating_System
Wii	I-Operating_System
's	O
controls	O
,	O
saying	O
that	O
the	O
game	O
played	O
to	O
the	O
console	O
's	O
strengths	O
.	O
</s>
<s>
General	O
opinion	O
was	O
positive	O
about	O
the	O
implementation	O
of	O
the	B-Operating_System
Wii	I-Operating_System
motion	O
controls	O
,	O
and	O
how	O
this	O
improved	O
on	O
the	O
control	O
scheme	O
and	O
difficulty	O
of	O
the	O
Nintendo	B-Device
DS	I-Device
original	O
.	O
</s>
