<s>
Tip-enhanced	B-Algorithm
Raman	I-Algorithm
spectroscopy	I-Algorithm
(	O
TERS	O
)	O
is	O
a	O
variant	O
of	O
surface-enhanced	B-Algorithm
Raman	I-Algorithm
spectroscopy	I-Algorithm
(	O
SERS	O
)	O
that	O
combines	O
scanning	O
probe	O
microscopy	O
with	O
Raman	B-Algorithm
spectroscopy	I-Algorithm
.	O
</s>
<s>
TERS	O
overcomes	O
these	O
limitations	O
as	O
the	O
Raman	B-Algorithm
spectrum	I-Algorithm
obtained	O
originates	O
primarily	O
from	O
the	O
molecules	O
within	O
a	O
few	O
tens	O
of	O
nanometers	O
of	O
the	O
tip	O
.	O
</s>
<s>
The	O
earliest	O
reports	O
of	O
tip	O
enhanced	O
Raman	B-Algorithm
spectroscopy	I-Algorithm
typically	O
used	O
a	O
Raman	O
microscope	O
coupled	O
with	O
an	O
atomic	O
force	O
microscope	O
.	O
</s>
<s>
Tip-enhanced	B-Algorithm
Raman	I-Algorithm
spectroscopy	I-Algorithm
coupled	O
with	O
a	O
scanning	O
tunneling	O
microscope	O
(	O
STM-TERS	O
)	O
has	O
also	O
become	O
a	O
reliable	O
technique	O
,	O
since	O
it	O
utilizes	O
the	O
gap	O
mode	O
plasmon	O
between	O
the	O
metallic	O
probe	O
and	O
the	O
metallic	O
substrate	O
.	O
</s>
<s>
Tip-enhanced	B-Algorithm
Raman	I-Algorithm
spectroscopy	I-Algorithm
requires	O
a	O
confocal	O
microscope	O
,	O
and	O
a	O
scanning	O
probe	O
microscope	O
.	O
</s>
