<s>
Time	O
Aware	O
LSTM	B-Algorithm
(	O
T-LSTM	O
)	O
is	O
a	O
long	B-Algorithm
short-term	I-Algorithm
memory	I-Algorithm
(	O
LSTM	B-Algorithm
)	O
unit	O
capable	O
of	O
handling	O
irregular	O
time	O
intervals	O
in	O
longitudinal	O
patient	O
records	O
.	O
</s>
<s>
T-LSTM	O
was	O
developed	O
by	O
researchers	O
from	O
Michigan	O
State	O
University	O
,	O
IBM	O
Research	O
,	O
and	O
Cornell	O
University	O
and	O
was	O
first	O
presented	O
in	O
the	O
Knowledge	O
Discovery	O
and	O
Data	O
Mining	O
(	O
KDD	O
)	O
conference	O
.	O
</s>
<s>
Experiments	O
using	O
real	O
and	O
synthetic	O
data	O
proved	O
that	O
T-LSTM	O
auto-encoder	O
outperformed	O
widely	O
used	O
frameworks	O
including	O
LSTM	B-Algorithm
and	O
MF1-LSTM	O
auto-encoders	O
.	O
</s>
