<s>
Tactile	B-Algorithm
corpuscles	I-Algorithm
or	O
Meissner	B-Algorithm
's	I-Algorithm
corpuscles	I-Algorithm
are	O
a	O
type	O
of	O
mechanoreceptor	O
discovered	O
by	O
anatomist	O
Georg	O
Meissner	O
(	O
1829	O
–	O
1905	O
)	O
and	O
Rudolf	O
Wagner	O
.	O
</s>
<s>
Tactile	B-Algorithm
corpuscles	I-Algorithm
are	O
encapsulated	O
myelinated	O
nerve	O
endings	O
,	O
surrounded	O
by	O
Schwann	O
cells	O
.	O
</s>
<s>
Feelings	O
of	O
deep	O
pressure	O
(	O
from	O
a	O
poke	O
,	O
for	O
instance	O
)	O
are	O
generated	O
from	O
lamellar	B-Algorithm
corpuscles	I-Algorithm
(	O
the	O
only	O
other	O
type	O
of	O
phasic	B-Architecture
tactile	O
mechanoreceptor	O
)	O
,	O
which	O
are	O
located	O
deeper	O
in	O
the	O
dermis	B-Algorithm
,	O
and	O
some	O
free	O
nerve	O
endings	O
.	O
</s>
<s>
Also	O
,	O
tactile	B-Algorithm
corpuscles	I-Algorithm
do	O
not	O
detect	O
noxious	O
stimuli	O
;	O
this	O
is	O
signaled	O
exclusively	O
by	O
free	O
nerve	O
endings	O
.	O
</s>
<s>
The	O
number	O
of	O
tactile	B-Algorithm
corpuscles	I-Algorithm
per	O
square	O
millimeter	O
of	O
human	O
skin	O
on	O
the	O
fingertips	O
drops	O
fourfold	O
between	O
the	O
ages	O
of	O
12	O
and	O
50	O
.	O
</s>
<s>
Tactile	B-Algorithm
corpuscles	I-Algorithm
are	O
rapidly	O
adapting	O
mechanoreceptors	O
.	O
</s>
<s>
Because	O
of	O
their	O
superficial	O
location	O
in	O
the	O
dermis	B-Algorithm
,	O
these	O
corpuscles	O
are	O
particularly	O
sensitive	O
to	O
touch	O
and	O
vibrations	O
,	O
but	O
for	O
the	O
same	O
reasons	O
,	O
they	O
are	O
limited	O
in	O
their	O
detection	O
because	O
they	O
can	O
only	O
signal	O
that	O
something	O
is	O
touching	O
the	O
skin	O
.	O
</s>
<s>
Any	O
physical	O
deformation	O
of	O
the	O
corpuscle	O
will	O
cause	O
sodium	O
ions	O
to	O
enter	O
it	O
,	O
creating	O
an	O
action	B-Algorithm
potential	I-Algorithm
in	O
the	O
corpuscle	O
's	O
nerve	O
fiber	O
.	O
</s>
<s>
Since	O
they	O
are	O
rapidly	O
adapting	O
or	O
phasic	B-Architecture
,	O
the	O
action	B-Algorithm
potentials	I-Algorithm
generated	O
quickly	O
decrease	O
and	O
eventually	O
cease	O
(	O
this	O
is	O
the	O
reason	O
one	O
stops	O
"	O
feeling	O
"	O
one	O
's	O
clothes	O
)	O
.	O
</s>
<s>
:	O
while	O
physically	O
reforming	O
)	O
causes	O
another	O
volley	O
of	O
action	B-Algorithm
potentials	I-Algorithm
to	O
be	O
generated	O
.	O
</s>
