<s>
Stretta	B-Algorithm
is	O
a	O
minimally	O
invasive	O
endoscopic	O
procedure	O
for	O
the	O
treatment	O
of	O
gastroesophageal	O
reflux	O
disease	O
(	O
GERD	O
)	O
that	O
delivers	O
radiofrequency	O
energy	O
in	O
the	O
form	O
of	O
electromagnetic	O
waves	O
through	O
electrodes	O
at	O
the	O
end	O
of	O
a	O
catheter	O
to	O
the	O
lower	O
esophageal	O
sphincter	O
(	O
LES	O
)	O
and	O
the	O
gastric	O
cardia	O
–	O
the	O
region	O
of	O
the	O
stomach	O
just	O
below	O
the	O
LES	O
.	O
</s>
<s>
In	O
2015	O
an	O
American	O
Society	O
for	O
Gastrointestinal	O
Endoscopy	O
guideline	O
noted	O
that	O
the	O
quality	O
of	O
evidence	O
was	O
low	O
for	O
Stretta	B-Algorithm
and	O
the	O
other	O
available	O
endoscopic	O
treatment	O
for	O
GERD	O
(	O
transoral	B-Algorithm
incisionless	I-Algorithm
fundoplication	I-Algorithm
)	O
and	O
called	O
for	O
better	O
research	O
to	O
be	O
conducted	O
;	O
it	O
suggested	O
that	O
endoscopic	O
treatments	O
for	O
GERD	O
be	O
considered	O
.	O
</s>
<s>
One	O
was	O
a	O
systematic	O
review	O
and	O
meta-analysis	O
of	O
clinical	O
trials	O
conducted	O
with	O
Stretta	B-Algorithm
,	O
done	O
in	O
response	O
to	O
the	O
2013	O
SAGES	O
review	O
(	O
which	O
did	O
not	O
include	O
meta-analysis	O
)	O
.	O
</s>
<s>
However	O
,	O
there	O
does	O
not	O
appear	O
to	O
be	O
any	O
sustained	O
improvement	O
in	O
objective	O
outcomes	O
and	O
there	O
is	O
no	O
evidence	O
that	O
Stretta	B-Algorithm
results	O
in	O
improved	O
outcomes	O
as	O
compared	O
to	O
surgical	O
intervention	O
.	O
</s>
<s>
A	O
more	O
recent	O
study	O
published	O
in	O
2020	O
evaluated	O
25	O
patients	O
post	O
Stretta	B-Algorithm
Procedure	I-Algorithm
and	O
the	O
results	O
concluded	O
significant	O
improvement	O
in	O
reflux	O
symptoms	O
and	O
quality	O
of	O
life	O
,	O
lowering	O
Heartburn	O
Score	O
(	O
DeMeester	O
score	O
)	O
from	O
3.7	O
in	O
women	O
and	O
4.0	O
in	O
men	O
to	O
1.6	O
±1	O
(	O
p	O
=	O
0.05	O
)	O
in	O
women	O
and	O
1.68	O
±	O
1.19	O
(	O
p	O
=	O
0.05	O
)	O
in	O
men	O
.	O
</s>
