<s>
StatsDirect	B-Algorithm
is	O
a	O
statistical	B-Algorithm
software	I-Algorithm
package	I-Algorithm
designed	O
for	O
biomedical	O
,	O
public	O
health	O
,	O
and	O
general	O
health	O
science	O
uses	O
.	O
</s>
<s>
StatsDirect	B-Algorithm
's	O
interface	O
is	O
menu	O
driven	O
and	O
has	O
editors	O
for	O
spreadsheet-like	O
data	O
and	O
reports	O
.	O
</s>
<s>
The	O
function	O
library	O
includes	O
common	O
medical	O
statistical	O
methods	O
that	O
can	O
be	O
extended	O
by	O
users	O
via	O
an	O
XML-based	O
description	O
that	O
can	O
embed	O
calls	O
to	O
native	O
StatsDirect	B-Algorithm
numerical	O
libraries	O
,	O
R	B-Language
scripts	O
,	O
or	O
algorithms	O
in	O
any	O
of	O
the	O
.NET	B-Application
languages	O
(	O
such	O
as	O
C#	B-Application
,	O
VB.Net	B-Language
,	O
J#	B-Language
,	O
or	O
F#	B-Operating_System
)	O
.	O
</s>
<s>
For	O
example	O
,	O
users	O
can	O
perform	O
a	O
chi-square	B-General_Concept
test	I-General_Concept
on	O
a	O
two-by-two	O
table	O
,	O
but	O
they	O
are	O
asked	O
whether	O
the	O
data	O
are	O
from	O
a	O
cohort	O
(	O
perspective	O
)	O
or	O
case-control	O
(	O
retrospective	O
)	O
study	O
before	O
delivering	O
the	O
result	O
.	O
</s>
<s>
Both	O
processes	O
produce	O
a	O
chi-square	B-General_Concept
test	I-General_Concept
result	O
but	O
more	O
emphasis	O
is	O
put	O
on	O
the	O
appropriate	O
statistic	O
for	O
the	O
inference	O
,	O
which	O
is	O
the	O
odds	O
ratio	O
for	O
retrospective	O
studies	O
and	O
relative	O
risk	O
for	O
prospective	O
studies	O
.	O
</s>
<s>
Arcus	O
Quickstat	O
for	O
Windows	B-Application
followed	O
in	O
1999	O
.	O
</s>
<s>
In	O
2000	O
,	O
an	O
expanded	O
version	O
,	O
StatsDirect	B-Algorithm
,	O
was	O
released	O
for	O
Microsoft	B-Application
Windows	I-Application
.	O
</s>
<s>
In	O
2013	O
,	O
the	O
third	O
generation	O
of	O
this	O
software	O
was	O
released	O
,	O
written	O
in	O
C#	B-Application
for	O
the	O
.NET	B-Application
platform	I-Application
.	O
</s>
<s>
StatsDirect	B-Algorithm
reports	O
embed	O
the	O
metadata	O
necessary	O
to	O
replay	O
calculations	O
,	O
which	O
may	O
be	O
needed	O
if	O
the	O
original	O
data	O
is	O
ever	O
updated	O
.	O
</s>
<s>
The	O
reproducible	O
report	O
technology	O
follows	O
the	O
research	B-Application
object	I-Application
approach	O
for	O
replaying	O
in	O
"	O
eLabs	O
"	O
.	O
</s>
