<s>
A	O
slow-wave	B-Algorithm
potential	I-Algorithm
is	O
a	O
rhythmic	O
electrophysiological	O
event	O
in	O
the	O
gastrointestinal	O
tract	O
.	O
</s>
<s>
In	O
the	O
human	O
enteric	O
nervous	O
system	O
,	O
the	O
slow-wave	B-Algorithm
threshold	I-Algorithm
is	O
the	O
slow-wave	B-Algorithm
potential	I-Algorithm
which	O
must	O
be	O
reached	O
before	O
a	O
slow	O
wave	O
can	O
be	O
propagated	O
in	O
gut	O
wall	O
smooth	O
muscle	O
.	O
</s>
<s>
When	O
the	O
amplitude	O
of	O
slow	O
waves	O
in	O
smooth	O
muscle	O
cells	O
reaches	O
the	O
slow-wave	B-Algorithm
threshold	I-Algorithm
—	O
the	O
L-type	O
Ca2+	O
channels	O
are	O
activated	O
,	O
resulting	O
in	O
calcium	O
influx	O
and	O
initiation	O
of	O
motility	O
.	O
</s>
<s>
In	O
gastrointestinal	O
smooth	O
muscle	O
,	O
the	O
slow-wave	B-Algorithm
threshold	I-Algorithm
can	O
be	O
altered	O
by	O
input	O
from	O
endogenous	O
and	O
exogenous	O
innervation	O
,	O
as	O
well	O
as	O
excitatory	O
(	O
acetylcholine	O
and	O
Substance	O
P	O
)	O
and	O
inhibitory	O
(	O
vasoactive	O
intestinal	O
peptide	O
and	O
nitric	O
oxide	O
)	O
compounds	O
.	O
</s>
