<s>
The	O
program	O
ShelXle	B-Application
is	O
a	O
graphical	O
user	O
interface	O
for	O
the	O
structure	O
refinement	O
program	O
SHELXL	O
.	O
</s>
<s>
ShelXle	B-Application
combines	O
an	O
editor	O
with	O
syntax	O
highlighting	O
for	O
the	O
SHELXL-associated	O
(	O
input	O
)	O
and	O
(	O
output	O
)	O
files	O
with	O
an	O
interactive	O
graphical	O
display	O
for	O
visualization	O
of	O
a	O
three-dimensional	O
structure	O
including	O
the	O
electron	O
density	O
(	O
Fo	O
)	O
and	O
difference	O
density	O
(	O
Fo-Fc	O
)	O
maps	O
.	O
</s>
<s>
ShelXle	B-Application
can	O
display	O
electron	O
density	O
maps	O
like	O
the	O
macromolecular	O
program	O
Coot	B-Language
but	O
is	O
more	O
intended	O
for	O
smaller	O
molecules	O
.	O
</s>
<s>
ShelXle	B-Application
is	O
free	B-Application
software	I-Application
,	O
distributed	O
under	O
the	O
GNU	B-Application
LGPL	I-Application
.	O
</s>
<s>
It	O
is	O
available	O
from	O
the	O
ShelXle	B-Application
website	O
or	O
from	O
SourceForge	B-Application
.	O
</s>
<s>
Binaries	O
are	O
available	O
for	O
Windows	B-Application
,	O
macOS	B-Application
and	O
the	O
Linux	B-Application
distributions	O
SuSE	O
,	O
Debian	O
and	O
Ubuntu	B-Operating_System
.	O
</s>
<s>
The	O
Windows	B-Application
binary	O
is	O
distributed	O
with	O
the	O
NSIS	B-Language
Installer	I-Language
.	O
</s>
<s>
ShelXle	B-Application
uses	O
the	O
Qt	B-Language
(	O
framework	O
)	O
.	O
</s>
<s>
It	O
is	O
written	O
entirely	O
in	O
C++	B-Language
and	O
does	O
not	O
use	O
any	O
scripting	B-Language
language	I-Language
.	O
</s>
