<s>
A	O
sequence	B-Application
profiling	I-Application
tool	I-Application
in	O
bioinformatics	O
is	O
a	O
type	O
of	O
software	O
that	O
presents	O
information	O
related	O
to	O
a	O
genetic	O
sequence	O
,	O
gene	O
name	O
,	O
or	O
keyword	O
input	O
.	O
</s>
<s>
Many	O
sequence	B-Application
profiling	I-Application
tools	I-Application
are	O
software	O
portals	O
or	O
gateways	O
that	O
simplify	O
the	O
process	O
of	O
finding	O
information	O
about	O
a	O
query	O
in	O
the	O
large	O
and	O
growing	O
number	O
of	O
bioinformatics	O
databases	O
.	O
</s>
<s>
The	O
"	O
post-genomics	O
"	O
era	O
has	O
given	O
rise	O
to	O
a	O
range	O
of	O
web-based	O
tools	O
and	O
software	O
to	O
compile	O
,	O
organize	O
,	O
and	O
deliver	O
large	O
amounts	O
of	O
primary	O
sequence	O
information	O
,	O
as	O
well	O
as	O
protein	O
structures	O
,	O
gene	O
annotations	O
,	O
sequence	B-Algorithm
alignments	I-Algorithm
,	O
and	O
other	O
common	O
bioinformatics	O
tasks	O
.	O
</s>
<s>
For	O
example	O
,	O
users	O
might	O
use	O
the	O
sequence	B-Algorithm
alignment	I-Algorithm
and	O
search	O
tool	O
BLAST	B-Application
to	O
identify	O
homologs	O
of	O
their	O
gene	O
of	O
interest	O
in	O
other	O
species	O
,	O
and	O
then	O
use	O
these	O
results	O
to	O
locate	O
a	O
solved	O
protein	O
structure	O
for	O
one	O
of	O
the	O
homologs	O
.	O
</s>
<s>
Sequence	B-Application
profiling	I-Application
tools	I-Application
serve	O
to	O
automate	O
and	O
integrate	O
the	O
process	O
of	O
seeking	O
such	O
disparate	O
information	O
by	O
rendering	O
the	O
process	O
of	O
searching	O
several	O
different	O
external	O
databases	O
transparent	O
to	O
the	O
user	O
.	O
</s>
<s>
Advantages	O
of	O
sequence	B-Application
profiling	I-Application
tools	I-Application
include	O
the	O
ability	O
to	O
use	O
multiple	O
of	O
these	O
specialized	O
tools	O
in	O
a	O
single	O
query	O
and	O
present	O
the	O
output	O
with	O
a	O
common	O
interface	O
,	O
the	O
ability	O
to	O
direct	O
the	O
output	O
of	O
one	O
set	O
of	O
tools	O
or	O
database	O
searches	O
into	O
the	O
input	O
of	O
another	O
,	O
and	O
the	O
capacity	O
to	O
disseminate	O
hosting	O
and	O
compilation	O
obligations	O
to	O
a	O
network	O
of	O
research	O
groups	O
and	O
institutions	O
rather	O
than	O
a	O
single	O
centralized	O
repository	O
.	O
</s>
<s>
Profiling	O
tools	O
based	O
on	O
keyword	O
searches	O
are	O
essentially	O
search	B-Application
engines	I-Application
that	O
are	O
highly	O
specialized	O
for	O
bioinformatics	O
work	O
,	O
thereby	O
eliminating	O
a	O
clutter	O
of	O
irrelevant	O
or	O
non-scholarly	O
hits	O
that	O
might	O
occur	O
with	O
a	O
traditional	O
search	B-Application
engine	I-Application
like	O
Google	B-Application
.	I-Application
</s>
<s>
For	O
example	O
,	O
the	O
NCBI	O
search	B-Application
engine	I-Application
Entrez	O
segregates	O
its	O
hits	O
by	O
category	O
,	O
so	O
that	O
users	O
looking	O
for	O
protein	O
structure	O
information	O
can	O
screen	O
out	O
sequences	O
with	O
no	O
corresponding	O
structure	O
,	O
while	O
users	O
interested	O
in	O
perusing	O
the	O
literature	O
on	O
a	O
subject	O
can	O
view	O
abstracts	O
of	O
papers	O
published	O
in	O
scholarly	O
journals	O
without	O
distraction	O
from	O
gene	O
or	O
sequence	O
results	O
.	O
</s>
<s>
The	O
PubMed	B-Library
biosciences	O
literature	O
database	O
is	O
a	O
popular	O
tool	O
for	O
literature	O
searches	O
,	O
though	O
this	O
service	O
is	O
nearly	O
equaled	O
with	O
the	O
more	O
general	O
Google	B-Library
Scholar	I-Library
.	O
</s>
<s>
Keyword-based	O
data	O
aggregation	O
services	O
like	O
the	O
Bioinformatic	B-Application
Harvester	I-Application
performs	O
provide	O
reports	O
from	O
a	O
variety	O
of	O
third-party	O
servers	O
in	O
an	O
as-is	O
format	O
so	O
that	O
users	O
need	O
not	O
visit	O
the	O
website	O
or	O
install	O
the	O
software	O
for	O
each	O
individual	O
component	O
service	O
.	O
</s>
<s>
A	O
typical	O
sequence	B-Application
profiling	I-Application
tool	I-Application
carries	O
this	O
further	O
by	O
using	O
an	O
actual	O
DNA	O
,	O
RNA	O
,	O
or	O
protein	O
sequence	O
as	O
an	O
input	O
and	O
allows	O
the	O
user	O
to	O
visit	O
different	O
web-based	O
analysis	O
tools	O
to	O
obtain	O
the	O
information	O
desired	O
.	O
</s>
<s>
In	O
another	O
public-database	O
example	O
,	O
the	O
BLAST	B-Application
sequence	O
search	O
report	O
from	O
NCBI	O
provides	O
a	O
link	O
from	O
its	O
alignment	O
report	O
to	O
other	O
relevant	O
information	O
in	O
its	O
own	O
databases	O
,	O
if	O
such	O
specific	O
information	O
exists	O
.	O
</s>
<s>
Sequerome	B-Application
,	O
a	O
public	O
service	O
tool	O
,	O
links	O
the	O
entire	O
BLAST	B-Application
report	O
to	O
many	O
third	O
party	O
servers/sites	O
that	O
provide	O
highly	O
specific	O
services	O
in	O
sequence	O
manipulations	O
such	O
as	O
restriction	O
enzyme	O
maps	O
,	O
open	O
reading	O
frame	O
analyses	O
for	O
nucleotide	O
sequences	O
,	O
and	O
secondary	O
structure	O
prediction	O
.	O
</s>
<s>
Consequently	O
,	O
future	O
generation	O
of	O
sequence	B-Application
profiling	I-Application
tools	I-Application
would	O
include	O
ability	O
to	O
collaborate	O
online	O
with	O
researchers	O
to	O
share	O
project	O
logs	O
and	O
research	O
tools	O
,	O
annotate	O
results	O
of	O
sequence	O
analysis	O
or	O
lab	O
work	O
,	O
customize	O
and	O
automate	O
the	O
processing	O
of	O
sets	O
of	O
sequence	O
data	O
etc	O
.	O
</s>
<s>
is	O
a	O
Google	B-Application
powered	O
search	O
tool	O
that	O
allows	O
the	O
user	O
to	O
directly	O
enter	O
a	O
sequence	O
and	O
search	O
the	O
entire	O
World	O
Wide	O
Web	O
.	O
</s>
<s>
This	O
unique	O
search	B-Application
engine	I-Application
,	O
which	O
is	O
the	O
only	O
one	O
of	O
its	O
kind	O
,	O
is	O
in	O
contrast	O
to	O
searching	O
specific	O
databases	O
e.g.	O
</s>
