<s>
SCHEMA	B-Algorithm
is	O
a	O
computational	O
algorithm	O
used	O
in	O
protein	O
engineering	O
to	O
identify	O
fragments	O
of	O
proteins	O
(	O
called	O
schemas	B-Algorithm
)	O
that	O
can	O
be	O
recombined	O
without	O
disturbing	O
the	O
integrity	O
of	O
the	O
proteins	O
 '	O
three-dimensional	O
structure	O
.	O
</s>
<s>
By	O
minimizing	O
these	O
disruptions	O
,	O
SCHEMA	B-Algorithm
can	O
be	O
used	O
to	O
engineer	O
chimeric	O
proteins	O
that	O
stably	O
fold	O
and	O
may	O
have	O
altered	O
function	O
relative	O
to	O
their	O
parent	O
proteins	O
.	O
</s>
<s>
SCHEMA	B-Algorithm
algorithm	O
has	O
been	O
applied	O
in	O
the	O
recombinant	O
libraries	O
of	O
distantly	O
related	O
β-lactamases	O
.	O
</s>
