<s>
RTI-121	B-Algorithm
is	O
a	O
phenyltropane	O
based	O
,	O
highly	O
selective	O
dopamine	O
reuptake	O
inhibitor	O
and	O
is	O
derived	O
from	O
methylecgonidine	O
.	O
</s>
<s>
RTI-121	B-Algorithm
is	O
a	O
potent	O
and	O
long-lasting	O
stimulant	O
,	O
producing	O
stimulant	O
effects	O
for	O
more	O
than	O
10	O
hours	O
after	O
a	O
single	O
dose	O
in	O
mice	O
which	O
would	O
limit	O
its	O
potential	O
uses	O
in	O
humans	O
,	O
as	O
it	O
might	O
have	O
significant	O
abuse	O
potential	O
if	O
used	O
outside	O
a	O
medical	O
setting	O
.	O
</s>
<s>
However	O
RTI-121	B-Algorithm
occupies	O
the	O
dopamine	O
transporter	O
more	O
slowly	O
than	O
cocaine	B-Application
,	O
and	O
so	O
might	O
have	O
lower	O
abuse	O
potential	O
than	O
cocaine	B-Application
itself	O
.	O
</s>
<s>
RTI-121	B-Algorithm
is	O
mainly	O
used	O
in	O
scientific	O
research	O
into	O
the	O
dopamine	O
reuptake	O
transporter	O
.	O
</s>
<s>
It	O
is	O
more	O
selective	O
for	O
the	O
dopamine	O
transporter	O
than	O
other	O
DAT	O
radioligands	O
such	O
as	O
β-CIT	B-Language
,	O
and	O
so	O
has	O
less	O
nonspecific	O
binding	O
and	O
produces	O
"	O
cleaner	O
"	O
images	O
.	O
</s>
<s>
Various	O
radiolabelled	O
forms	O
of	O
RTI-121	B-Algorithm
(	O
with	O
different	O
radioactive	O
isotopes	O
of	O
iodine	O
used	O
depending	O
on	O
the	O
application	O
)	O
are	O
used	O
in	O
both	O
humans	O
and	O
animals	O
to	O
map	O
the	O
distribution	O
of	O
dopamine	O
transporters	O
in	O
the	O
brain	O
.	O
</s>
<s>
RTI-121	B-Algorithm
not	O
specified	O
as	O
controlled	O
substance	O
in	O
any	O
country	O
as	O
of	O
2007	O
.	O
</s>
<s>
Some	O
jurisdictions	O
such	O
as	O
the	O
United	O
States	O
,	O
Australia	O
,	O
and	O
New	O
Zealand	O
,	O
however	O
,	O
might	O
however	O
consider	O
RTI-121	B-Algorithm
to	O
be	O
a	O
controlled	O
substance	O
analogue	O
of	O
cocaine	B-Application
on	O
the	O
grounds	O
of	O
its	O
related	O
chemical	O
structure	O
.	O
</s>
