<s>
OpenEpi	B-Application
is	O
a	O
free	B-Application
,	O
web-based	B-Application
,	O
open	O
source	O
,	O
operating	O
system-independent	O
series	O
of	O
programs	O
for	O
use	O
in	O
epidemiology	O
,	O
biostatistics	O
,	O
public	O
health	O
,	O
and	O
medicine	O
,	O
providing	O
a	O
number	O
of	O
epidemiologic	O
and	O
statistical	O
tools	O
for	O
summary	O
data	O
.	O
</s>
<s>
OpenEpi	B-Application
was	O
developed	O
in	O
JavaScript	B-Language
and	O
HTML	B-Language
,	O
and	O
can	O
be	O
run	O
in	O
modern	O
web	B-Application
browsers	I-Application
.	O
</s>
<s>
The	O
program	O
can	O
be	O
run	O
from	O
the	O
OpenEpi	B-Application
website	O
or	O
downloaded	O
and	O
run	O
without	O
a	O
web	O
connection	O
.	O
</s>
<s>
OpenEpi	B-Application
has	O
been	O
reviewed	O
,	O
both	O
by	O
media	O
organizations	O
and	O
in	O
research	O
journals	O
.	O
</s>
<s>
The	O
OpenEpi	B-Application
developers	O
have	O
had	O
extensive	O
experience	O
in	O
the	O
development	O
and	O
testing	O
of	O
Epi	B-Application
Info	I-Application
,	O
a	O
program	O
developed	O
by	O
the	O
Centers	O
for	O
Disease	O
Control	O
and	O
Prevention	O
(	O
CDC	O
)	O
and	O
widely	O
used	O
around	O
the	O
world	O
for	O
data	O
entry	O
and	O
analysis	O
.	O
</s>
<s>
OpenEpi	B-Application
was	O
developed	O
to	O
perform	O
analyses	O
found	O
in	O
the	O
DOS	B-Device
version	O
of	O
Epi	B-Application
Info	I-Application
modules	O
StatCalc	O
and	O
EpiTable	O
,	O
to	O
improve	O
upon	O
the	O
types	O
of	O
analyses	O
provided	O
by	O
these	O
modules	O
,	O
and	O
to	O
provide	O
a	O
number	O
of	O
tools	O
and	O
calculations	O
not	O
currently	O
available	O
in	O
Epi	B-Application
Info	I-Application
.	O
</s>
<s>
It	O
is	O
the	O
first	O
step	O
toward	O
an	O
entirely	O
web-based	B-Application
set	O
of	O
epidemiologic	O
software	O
tools	O
.	O
</s>
<s>
OpenEpi	B-Application
can	O
be	O
thought	O
of	O
as	O
an	O
important	O
companion	O
to	O
Epi	B-Application
Info	I-Application
and	O
to	O
other	O
programs	O
such	O
as	O
SAS	B-Language
,	O
PSPP	B-Language
,	O
SPSS	B-Algorithm
,	O
Stata	B-Algorithm
,	O
SYSTAT	B-Language
,	O
Minitab	B-Application
,	O
Epidata	B-Algorithm
,	O
and	O
R	B-Language
(	O
see	O
the	O
R	B-Language
programming	I-Language
language	I-Language
)	O
.	O
</s>
<s>
Another	O
functionally	O
similar	O
Windows-based	O
program	O
is	O
Winpepi	B-Algorithm
.	O
</s>
<s>
See	O
also	O
list	B-Algorithm
of	I-Algorithm
statistical	I-Algorithm
packages	I-Algorithm
and	O
comparison	O
of	O
statistical	B-Algorithm
packages	I-Algorithm
.	O
</s>
<s>
Both	O
OpenEpi	B-Application
and	O
Epi	B-Application
Info	I-Application
were	O
developed	O
with	O
the	O
goal	O
of	O
providing	O
tools	O
for	O
low	O
and	O
moderate	O
resource	O
areas	O
of	O
the	O
world	O
.	O
</s>
<s>
The	O
initial	O
development	O
of	O
OpenEpi	B-Application
was	O
supported	O
by	O
a	O
grant	O
from	O
the	O
Bill	O
and	O
Melinda	O
Gates	O
Foundation	O
to	O
Emory	O
University	O
.	O
</s>
<s>
The	O
types	O
of	O
calculations	O
currently	O
performed	O
by	O
OpenEpi	B-Application
include	O
:	O
</s>
<s>
For	O
epidemiologists	O
and	O
other	O
health	O
researchers	O
,	O
OpenEpi	B-Application
performs	O
a	O
number	O
of	O
calculations	O
based	O
on	O
tables	O
not	O
found	O
in	O
most	O
epidemiologic	O
and	O
statistical	B-Algorithm
packages	I-Algorithm
.	O
</s>
<s>
For	O
example	O
,	O
for	O
a	O
single	O
2x2	O
table	O
,	O
in	O
addition	O
to	O
the	O
results	O
presented	O
in	O
other	O
programs	O
,	O
OpenEpi	B-Application
provides	O
estimates	O
for	O
:	O
</s>
<s>
For	O
stratified	O
2x2	O
tables	O
with	O
count	O
data	O
,	O
OpenEpi	B-Application
provides	O
:	O
</s>
<s>
Similar	O
to	O
Epi	B-Application
Info	I-Application
,	O
in	O
a	O
stratified	O
analysis	O
,	O
both	O
crude	O
and	O
adjusted	O
estimates	O
are	O
provided	O
so	O
that	O
the	O
assessment	O
of	O
confounding	O
can	O
be	O
made	O
.	O
</s>
<s>
With	O
rate	O
data	O
,	O
OpenEpi	B-Application
provides	O
adjusted	O
rate	O
ratio	O
's	O
and	O
rate	O
differences	O
,	O
and	O
tests	O
for	O
interaction	O
.	O
</s>
<s>
Finally	O
,	O
with	O
count	O
data	O
,	O
OpenEpi	B-Application
also	O
performs	O
a	O
test	O
for	O
trend	O
,	O
for	O
both	O
crude	O
data	O
and	O
stratified	O
data	O
.	O
</s>
<s>
In	O
addition	O
to	O
being	O
used	O
to	O
analyze	O
data	O
by	O
health	O
researchers	O
,	O
OpenEpi	B-Application
has	O
been	O
used	O
as	O
a	O
training	O
tool	O
for	O
teaching	O
epidemiology	O
to	O
students	O
at	O
:	O
Emory	O
University	O
,	O
University	O
of	O
Massachusetts	O
,	O
University	O
of	O
Michigan	O
,	O
University	O
of	O
Minnesota	O
,	O
Morehouse	O
College	O
,	O
Columbia	O
University	O
,	O
University	O
of	O
Wisconsin	O
,	O
San	O
Jose	O
State	O
University	O
,	O
University	O
of	O
Medicine	O
and	O
Dentistry	O
of	O
New	O
Jersey	O
,	O
University	O
of	O
Washington	O
,	O
and	O
elsewhere	O
.	O
</s>
<s>
Because	O
OpenEpi	B-Application
is	O
easy	O
to	O
use	O
,	O
requires	O
no	O
programming	O
experience	O
,	O
and	O
can	O
be	O
run	O
on	O
the	O
internet	O
,	O
students	O
can	O
use	O
the	O
program	O
and	O
focus	O
on	O
the	O
interpretation	O
of	O
results	O
.	O
</s>
<s>
The	O
developers	O
encourage	O
others	O
to	O
develop	O
modules	O
that	O
could	O
be	O
added	O
to	O
OpenEpi	B-Application
and	O
provide	O
a	O
developer	O
's	O
tool	O
at	O
the	O
website	O
.	O
</s>
