<s>
The	O
Neurophysiological	B-Algorithm
Biomarker	I-Algorithm
Toolbox	I-Algorithm
(	O
NBT	O
)	O
is	O
an	O
open	O
source	O
MATLAB	B-Language
toolbox	O
for	O
the	O
computation	O
and	O
integration	O
of	O
neurophysiological	O
biomarkers	O
(	O
e.g.	O
,	O
biomarkers	O
based	O
on	O
EEG	B-Application
or	O
MEG	B-Algorithm
recordings	O
)	O
.	O
</s>
<s>
The	O
NBT	O
toolbox	O
provides	O
unique	O
features	O
for	O
analysis	O
of	O
resting-state	O
EEG	B-Application
or	O
MEG	B-Algorithm
recordings	O
.	O
</s>
<s>
For	O
an	O
adequate	O
understanding	O
of	O
quantitative	O
changes	O
in	O
neurophysiological	O
signals	O
,	O
such	O
as	O
electroencephalography	B-Application
(	O
EEG	B-Application
)	O
or	O
magnetoencephalography	B-Algorithm
(	O
MEG	B-Algorithm
)	O
,	O
as	O
a	O
consequence	O
of	O
disease	O
,	O
experimental	O
manipulations	O
,	O
or	O
genetic	O
variability	O
there	O
is	O
a	O
need	O
to	O
apply	O
multiple	O
biomarker	O
algorithms	O
.	O
</s>
<s>
Originally	O
the	O
toolbox	O
was	O
aimed	O
at	O
biomarkers	O
based	O
on	O
EEG	B-Application
or	O
MEG	B-Algorithm
signals	O
,	O
recently	O
however	O
the	O
toolbox	O
has	O
moved	O
towards	O
supporting	O
almost	O
any	O
type	O
of	O
biomarker	O
data	O
.	O
</s>
<s>
The	O
biomarker	O
data	O
and	O
associated	O
meta	O
information	O
is	O
stored	O
in	O
a	O
Matlab-based	O
database	O
;	O
the	O
NBT	O
elements	O
database	O
.	O
</s>
<s>
The	O
NBT	O
toolbox	O
works	O
as	O
a	O
plugin	O
to	O
the	O
open-source	O
Matlab	B-Language
toolbox	O
EEGLAB	B-Algorithm
.	O
</s>
<s>
Commercial	O
EEG	B-Application
analysis	O
mainly	O
targeting	O
large	O
clinical	O
research	O
studies	O
or	O
clinical	O
trials	O
are	O
provided	O
as	O
an	O
.	O
</s>
