<s>
Little	B-Language
b	I-Language
is	O
a	O
domain-specific	B-Language
programming	I-Language
language	I-Language
,	O
more	O
specifically	O
,	O
a	O
modeling	B-Language
language	I-Language
,	O
designed	O
to	O
build	O
modular	O
mathematical	O
models	O
of	O
biological	O
systems	O
.	O
</s>
<s>
Little	B-Language
b	I-Language
is	O
being	O
developed	O
in	O
the	O
Virtual	O
Cell	O
Program	O
at	O
Harvard	O
Medical	O
School	O
,	O
headed	O
by	O
mathematician	O
Jeremy	O
Gunawardena	O
.	O
</s>
<s>
This	O
language	O
is	O
based	O
on	O
Lisp	B-Language
and	O
is	O
meant	O
to	O
allow	O
modular	O
programming	O
to	O
model	O
biological	O
systems	O
.	O
</s>
<s>
The	O
language	O
draws	O
on	O
techniques	O
from	O
artificial	O
intelligence	O
and	O
symbolic	O
mathematics	O
,	O
and	O
provides	O
syntactic	O
conveniences	O
derived	O
from	O
object-oriented	B-Language
languages	I-Language
.	O
</s>
<s>
The	O
language	O
was	O
originally	O
denoted	O
with	O
a	O
lowercase	O
b	B-Language
(	O
distinguishing	O
it	O
from	O
B	B-Language
,	O
the	O
predecessor	O
to	O
the	O
widely	O
used	O
C	B-Language
programming	I-Language
language	I-Language
)	O
,	O
but	O
the	O
name	O
was	O
eventually	O
changed	O
to	O
"	O
little	B-Language
b	I-Language
"	O
to	O
avoid	O
confusion	O
and	O
to	O
pay	O
homage	O
to	O
Smalltalk	B-Application
.	O
</s>
