<s>
Immune	B-Application
Attack	I-Application
is	O
an	O
educational	O
video	O
game	O
created	O
by	O
the	O
Federation	O
of	O
American	O
Scientists	O
and	O
Escape	O
Hatch	O
Entertainment	O
.	O
</s>
<s>
The	O
protagonist	O
of	O
Immune	B-Application
Attack	I-Application
is	O
a	O
teenaged	O
prodigy	O
in	O
the	O
near-future	O
with	O
a	O
unique	O
immunodeficiency	O
in	O
which	O
the	O
immune	O
system	O
is	O
"	O
present	O
,	O
yet	O
non-functional	O
"	O
-	O
as	O
if	O
all	O
the	O
immune	O
cells	O
have	O
forgotten	O
what	O
to	O
do	O
.	O
</s>
<s>
Each	O
subsequent	O
level	O
of	O
Immune	B-Application
Attack	I-Application
features	O
a	O
different	O
infection	O
,	O
and	O
a	O
different	O
cell	O
type	O
the	O
player	O
must	O
train	O
.	O
</s>
<s>
Immune	B-Application
Attack	I-Application
was	O
evaluated	O
in	O
5th	O
grade	O
though	O
12th	O
grade	O
classrooms	O
across	O
the	O
US	O
from	O
2009	O
through	O
2013	O
.	O
</s>
