<s>
Interferometric	O
reflectance	O
imaging	O
sensor	O
(	O
IRIS	B-Algorithm
)	O
,	O
formerly	O
known	O
as	O
the	O
spectral	O
reflectance	O
imaging	O
biosensor	O
(	O
SRIB	O
)	O
,	O
is	O
a	O
system	O
that	O
can	O
be	O
used	O
as	O
a	O
biosensing	O
platform	O
capable	O
of	O
high-throughput	O
multiplexing	O
of	O
protein	O
–	O
protein	O
,	O
protein	O
–	O
DNA	O
,	O
and	O
DNA	O
–	O
DNA	O
interactions	O
without	O
the	O
use	O
of	O
any	O
fluorescent	O
labels	O
.	O
</s>
<s>
IRIS	B-Algorithm
is	O
capable	O
of	O
quantifying	O
biomolecular	O
mass	O
accumulated	O
on	O
the	O
surface	O
.	O
</s>
<s>
The	O
reflection	O
intensity	O
is	O
imaged	O
using	O
a	O
CCD	B-Algorithm
or	O
CMOS	B-Device
camera	O
.	O
</s>
<s>
Applications	O
for	O
IRIS	B-Algorithm
include	O
microarray	O
format	O
immunoassays	O
,	O
single	O
nucleotide	O
polymorphism	O
(	O
SNP	O
)	O
detection	O
,	O
pathogen	O
detection	O
and	O
bio-defense	O
monitoring	O
,	O
kinetic	O
analysis	O
of	O
biomolecular	O
interactions	O
,	O
and	O
general	O
biomolecular	O
interaction	O
studies	O
for	O
research	O
applications	O
.	O
</s>
