<s>
HIVToolbox	B-Application
is	O
an	O
internet	O
application	O
that	O
helps	O
scientists	O
identify	O
and	O
develop	O
new	O
hypotheses	O
as	O
well	O
as	O
facilitate	O
interpretation	O
of	O
experiments	O
,	O
with	O
the	O
goal	O
of	O
helping	O
scientists	O
better	O
understand	O
HIV	O
,	O
the	O
virus	O
that	O
causes	O
AIDS	B-Device
,	O
and	O
to	O
identify	O
new	O
potential	O
drug	O
targets	O
.	O
</s>
<s>
HIVtoolbox	B-Application
is	O
an	O
internet	O
application	O
that	O
runs	O
off	O
of	O
a	O
MySQL	B-Application
database	O
designed	O
to	O
integrate	O
HIV	O
data	O
for	O
protein	O
sequences	O
derived	O
from	O
many	O
different	O
isolates	O
,	O
protein	O
structures	O
,	O
protein	O
domains	O
,	O
protein-protein	O
interactions	O
,	O
functional	O
elements	O
in	O
proteins	O
,	O
and	O
known	O
and	O
predicted	O
minimotifs	O
from	O
the	O
Minimotif	O
Miner	O
database	O
.	O
</s>
<s>
The	O
2nd	O
release	O
of	O
HIVToolbox	B-Application
,	O
HIVToolbox2	O
also	O
contains	O
information	O
about	O
the	O
locations	O
on	O
the	O
proteins	O
where	O
different	O
HIV	O
drugs	O
bind	O
,	O
and	O
their	O
spatial	O
relationship	O
to	O
the	O
mutations	O
that	O
arise	O
in	O
HIV	O
and	O
render	O
the	O
virus	O
resistant	O
to	O
the	O
drug	O
.	O
</s>
