<s>
GenMAPP	B-Application
(	O
Gene	O
Map	O
Annotator	O
and	O
Pathway	O
Profiler	O
)	O
is	O
a	O
free	O
,	O
open-source	B-Application
bioinformatics	O
software	O
tool	O
designed	O
to	O
visualize	O
and	O
analyze	O
genomic	O
data	O
in	O
the	O
context	O
of	O
pathways	O
(	O
metabolic	O
,	O
signaling	O
)	O
,	O
connecting	O
gene-level	O
datasets	O
to	O
biological	O
processes	O
and	O
disease	O
.	O
</s>
<s>
First	O
created	O
in	O
2000	O
,	O
GenMAPP	B-Application
is	O
developed	O
by	O
an	O
open-source	B-Application
team	O
based	O
in	O
an	O
academic	O
research	O
laboratory	O
.	O
</s>
<s>
GenMAPP	B-Application
maintains	O
databases	O
of	O
gene	O
identifiers	O
and	O
collections	O
of	O
pathway	O
maps	O
in	O
addition	O
to	O
visualization	O
and	O
analysis	O
tools	O
.	O
</s>
<s>
Together	O
with	O
other	O
public	O
resources	O
,	O
GenMAPP	B-Application
aims	O
to	O
provide	O
the	O
research	O
community	O
with	O
tools	O
to	O
gain	O
insight	O
into	O
biology	O
through	O
the	O
integration	O
of	O
data	O
types	O
ranging	O
from	O
genes	O
to	O
proteins	O
to	O
pathways	O
to	O
disease	O
.	O
</s>
<s>
GenMAPP	B-Application
was	O
first	O
created	O
in	O
2000	O
as	O
a	O
prototype	O
software	O
tool	O
in	O
the	O
laboratory	O
of	O
Bruce	O
Conklin	O
at	O
the	O
J	O
.	O
David	O
Gladstone	O
Institutes	O
in	O
San	O
Francisco	O
and	O
continues	O
to	O
be	O
developed	O
in	O
the	O
same	O
non-profit	O
,	O
academic	O
research	O
environment	O
.	O
</s>
<s>
The	O
first	O
release	O
version	O
of	O
GenMAPP	B-Application
1.0	O
was	O
available	O
in	O
2002	O
,	O
supporting	O
analysis	O
of	O
DNA	O
microarray	O
data	O
from	O
human	O
,	O
mouse	O
,	O
rat	O
and	O
yeast	O
.	O
</s>
<s>
In	O
2004	O
,	O
GenMAPP	B-Application
2.0	O
was	O
released	O
,	O
combining	O
the	O
previously	O
accessory	O
programs	O
MAPPFinder	O
and	O
MAPPBuilder	O
,	O
and	O
expanding	O
support	O
to	O
additional	O
species	O
.	O
</s>
<s>
GenMAPP	B-Application
2.1	O
was	O
released	O
in	O
2006	O
with	O
new	O
visualization	O
features	O
and	O
support	O
for	O
a	O
total	O
of	O
eleven	O
species	O
.	O
</s>
<s>
GenMAPP	B-Application
was	O
developed	O
by	O
biologists	O
and	O
is	O
focused	O
on	O
pathway	O
visualization	O
for	O
bench	O
biologists	O
.	O
</s>
<s>
Unlike	O
many	O
other	O
computational	O
systems	O
biology	O
tools	O
,	O
GenMAPP	B-Application
is	O
not	O
designed	O
for	O
cell/systems	O
modeling	O
;	O
it	O
focuses	O
on	O
the	O
immediate	O
needs	O
of	O
bench	O
biologists	O
by	O
enabling	O
them	O
to	O
rapidly	O
interpret	O
genomic	O
data	O
with	O
an	O
intuitive	O
,	O
easy-to-use	O
interface	O
.	O
</s>
<s>
GenMAPP	B-Application
is	O
implemented	O
in	O
Visual	B-Language
Basic	I-Language
6.0	I-Language
and	O
is	O
available	O
as	O
a	O
stand-alone	O
application	O
for	O
Microsoft	B-Application
Windows	I-Application
operating	I-Application
systems	I-Application
,	O
including	O
Boot	B-Application
Camp	I-Application
or	O
Parallels	B-Operating_System
Workstation	I-Operating_System
on	O
a	O
Mac	O
.	O
</s>
<s>
GenMAPP	B-Application
builds	O
and	O
maintains	O
gene	O
databases	O
for	O
a	O
variety	O
of	O
key	O
model	O
organisms	O
:	O
</s>
<s>
GenMAPP	B-Application
provides	O
tools	O
to	O
create	O
,	O
edit	O
and	O
annotate	O
biological	O
pathway	O
maps	O
.	O
</s>
<s>
GenMAPP	B-Application
allows	O
users	O
to	O
visualize	O
and	O
analyze	O
their	O
data	O
in	O
the	O
context	O
of	O
pathway	O
collections	O
and	O
the	O
Gene	O
Ontology	O
.	O
</s>
