<s>
GIMIAS	B-Language
is	O
a	O
workflow-oriented	O
environment	O
focused	O
on	O
biomedical	O
image	O
computing	O
and	O
simulation	B-Application
.	O
</s>
<s>
The	O
open-source	B-Application
framework	B-Architecture
is	O
extensible	O
through	O
plug-ins	B-Application
and	O
is	O
focused	O
on	O
building	O
research	O
and	O
clinical	O
software	O
prototypes	B-Application
.	O
</s>
<s>
GIMIAS	B-Language
is	O
being	O
funded	O
by	O
several	O
national	O
and	O
international	O
projects	O
like	O
cvREMOD	O
,	O
euHeart	O
or	O
VPH	O
NoE	O
.	O
</s>
<s>
GIMIAS	B-Language
stands	O
for	O
Graphical	B-Application
Interface	I-Application
for	O
Medical	B-Application
Image	I-Application
Analysis	O
and	O
Simulation	B-Application
.	O
</s>
<s>
GIMIAS	B-Language
provides	O
a	O
graphical	B-Application
user	I-Application
interface	I-Application
with	O
all	O
main	O
data	O
IO	O
,	O
visualization	O
and	O
interaction	O
functions	O
for	O
images	O
,	O
meshes	O
and	O
signals	O
.	O
</s>
<s>
GIMIAS	B-Language
features	O
include	O
:	O
</s>
<s>
Several	O
input	O
and	O
output	O
formats	O
:	O
DICOM	B-Algorithm
,	O
vtk	B-Language
,	O
stl	O
,	O
Nifty	O
,	O
Analyze	O
.	O
</s>
<s>
Clinical	O
workflow	B-Operating_System
navigation	O
that	O
can	O
help	O
the	O
user	O
to	O
navigate	O
from	O
patient	O
data	O
to	O
useful	O
information	O
for	O
patient	O
treatment	O
.	O
</s>
<s>
Other	O
additional	O
tools	O
for	O
image	B-Algorithm
segmentation	I-Algorithm
,	O
mesh	O
manipulation	O
and	O
signal	O
navigation	O
.	O
</s>
<s>
GIMIAS	B-Language
is	O
a	O
development	O
framework	B-Architecture
that	O
allows	O
developers	O
to	O
create	O
their	O
own	O
medical	O
applications	O
using	O
different	O
plug-ins	B-Application
that	O
can	O
be	O
dynamically	O
loaded	O
and	O
combined	O
.	O
</s>
<s>
The	O
prototypes	B-Application
developed	O
on	O
GIMIAS	B-Language
can	O
be	O
verified	O
by	O
end	O
users	O
in	O
real	O
scenarios	O
and	O
with	O
real	O
data	O
at	O
early	O
development	O
stages	O
.	O
</s>
<s>
Is	O
developed	O
using	O
C++	B-Language
language	I-Language
,	O
has	O
a	O
plug-in	B-Application
architecture	O
,	O
and	O
is	O
cross-platform	B-Operating_System
by	O
means	O
of	O
the	O
standard	O
CMake	B-Language
tool	O
.	O
</s>
<s>
Is	O
possible	O
to	O
integrate	O
new	O
libraries	O
using	O
CSnake	O
tool	O
and	O
is	O
based	O
on	O
common	O
open	O
source	O
libraries	O
like	O
VTK	B-Language
,	O
ITK	B-Language
,	O
MITK	O
,	O
BOOST	B-Language
and	O
wxWidgets	B-Language
.	O
</s>
<s>
A	O
plug-in	B-Application
can	O
extend	O
the	O
framework	B-Architecture
adding	O
new	O
processing	O
components	O
,	O
GUI	B-Application
components	O
like	O
toolbars	O
or	O
windows	B-Application
,	O
new	O
data	O
processing	O
types	O
or	O
new	O
rendering	O
libraries	O
.	O
</s>
<s>
GIMIAS	B-Language
supports	O
several	O
types	O
of	O
plug-ins	B-Application
,	O
starting	O
from	O
a	O
simple	O
DLL	O
,	O
a	O
3D	B-Application
Slicer	I-Application
compatible	O
command	O
line	O
plug-in	B-Application
or	O
a	O
more	O
complex	O
GIMIAS	B-Language
plug-in	B-Application
with	O
customized	O
graphical	B-Application
interface	I-Application
.	O
</s>
<s>
Automated	O
GUI	B-Application
generation	O
and	O
extensible	O
data	O
object	O
model	O
allow	O
to	O
share	O
plug-ins	B-Application
with	O
other	O
frameworks	O
and	O
empower	O
interoperability	O
.	O
</s>
<s>
The	O
software	O
is	O
available	O
on	O
Windows	B-Application
and	O
Linux	B-Application
,	O
64-bit	B-Device
and	O
32-bit	O
.	O
</s>
<s>
Initial	O
versions	O
of	O
the	O
open	O
source	O
framework	B-Architecture
was	O
released	O
by	O
the	O
end	O
of	O
2009	O
(	O
GIMIAS	B-Language
0.6.15	O
was	O
released	O
in	O
October	O
2009	O
)	O
.	O
</s>
<s>
In	O
2010	O
,	O
more	O
effort	O
was	O
done	O
to	O
empower	O
the	O
open	O
source	O
framework	B-Architecture
itself	O
,	O
providing	O
more	O
functionality	O
like	O
workflow	B-Operating_System
manager	O
,	O
3D	B-Application
Slicer	I-Application
plug-in	B-Application
compatibility	O
,	O
signal	O
viewer	O
and	O
customizable	O
views	O
.	O
</s>
<s>
GIMIAS	B-Language
version	O
0.8.1	O
,	O
1.0.0	O
,	O
1.1.0	O
and	O
1.2.0	O
were	O
released	O
during	O
this	O
year	O
.	O
</s>
<s>
GIMIAS	B-Language
Team	O
have	O
collaborated	O
with	O
:	O
</s>
<s>
GIMIAS	B-Language
is	O
one	O
of	O
the	O
tools	O
used	O
in	O
the	O
Virtual	O
Physiological	O
Human	O
.	O
</s>
<s>
AngioLab	O
is	O
a	O
software	O
tool	O
developed	O
within	O
the	O
GIMIAS	B-Language
framework	B-Architecture
and	O
is	O
part	O
of	O
a	O
more	O
ambitious	O
pipeline	O
for	O
the	O
integrated	O
management	O
of	O
cerebral	O
aneurysms	O
.	O
</s>
<s>
AngioLab	O
currently	O
includes	O
four	O
plug-ins	B-Application
:	O
angio	O
segmentation	B-Algorithm
,	O
angio	O
morphology	O
virtual	O
stenting	O
and	O
virtual	O
angiography	O
.	O
</s>
<s>
The	O
Automated	O
Morphological	O
Analysis	O
(	O
angio	O
morphology	O
plug-in	B-Application
)	O
and	O
the	O
Endovascular	O
Treatment	O
Planning	O
(	O
stenting	O
plug-in	B-Application
)	O
were	O
evaluated	O
.	O
</s>
<s>
CardioLab	O
:	O
The	O
CardioLab	O
suite	O
for	O
GIMIAS	B-Language
allows	O
performing	O
an	O
entire	O
workflow	B-Operating_System
from	O
medical	B-Application
images	I-Application
to	O
characterization	O
and	O
quantification	O
of	O
myocardial	O
diseases	O
and	O
Cardiac	O
Resynchronization	O
Therapy	O
(	O
CRT	O
)	O
planning	O
.	O
</s>
<s>
FocusDET	O
was	O
developed	O
using	O
GIMIAS	B-Language
facilities	O
.	O
</s>
