<s>
The	O
Fiocruz	B-Operating_System
Genome	I-Operating_System
Comparison	I-Operating_System
Project	I-Operating_System
is	O
a	O
collaborative	O
effort	O
involving	O
Brazil	O
's	O
Oswaldo	O
Cruz	O
Institute	O
and	O
IBM	O
's	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
,	O
designed	O
to	O
produce	O
a	O
database	O
comparing	O
the	O
genes	O
from	O
many	O
genomes	O
with	O
each	O
other	O
using	O
SSEARCH	O
.	O
</s>
<s>
The	O
program	O
SSEARCH	O
performs	O
a	O
rigorous	O
Smith	B-Algorithm
–	I-Algorithm
Waterman	I-Algorithm
alignment	I-Algorithm
between	O
a	O
protein	O
sequence	O
and	O
another	O
protein	O
sequence	O
,	O
a	O
protein	O
database	O
,	O
a	O
DNA	O
or	O
a	O
DNA	O
library	O
.	O
</s>
<s>
The	O
nature	O
of	O
the	O
computation	O
in	O
the	O
project	O
allows	O
it	O
to	O
easily	O
take	O
advantage	O
of	O
volunteer	B-Operating_System
computing	I-Operating_System
.	O
</s>
<s>
This	O
,	O
along	O
with	O
the	O
likely	O
humanitarian	O
benefits	O
of	O
the	O
research	O
,	O
has	O
led	O
the	O
World	B-Operating_System
Community	I-Operating_System
Grid	I-Operating_System
(	O
a	O
volunteer	B-Operating_System
computing	I-Operating_System
grid	O
that	O
uses	O
idle	O
computer	O
clock	O
time	O
)	O
to	O
run	O
the	O
Fiocruz	O
project	O
.	O
</s>
<s>
The	O
Genome	B-Operating_System
Comparison	I-Operating_System
Project	O
performs	O
a	O
complete	O
pairwise	O
comparison	O
between	O
all	O
predicted	O
protein	O
sequences	O
,	O
obtaining	O
indices	O
used	O
(	O
together	O
with	O
standardized	O
Gene	O
Ontology	O
)	O
as	O
a	O
reference	O
repository	O
for	O
the	O
annotator	O
community	O
.	O
</s>
<s>
The	O
sequence	O
similarity	O
comparison	O
program	O
used	O
in	O
the	O
Genome	B-Operating_System
Comparison	I-Operating_System
Project	O
is	O
called	O
SSEARCH	O
.	O
</s>
<s>
This	O
program	O
mathematically	O
finds	O
best	O
local	B-Algorithm
alignment	I-Algorithm
between	O
sequence	O
pairs	O
,	O
and	O
is	O
a	O
freely	O
available	O
implementation	O
of	O
the	O
Smith	B-Algorithm
–	I-Algorithm
Waterman	I-Algorithm
algorithm	I-Algorithm
.	O
</s>
