<s>
Cytoscape	B-Language
is	O
an	O
open	B-Application
source	I-Application
bioinformatics	O
software	B-Device
platform	I-Device
for	O
visualizing	B-Application
molecular	O
interaction	O
networks	O
and	O
integrating	O
with	O
gene	O
expression	O
profiles	O
and	O
other	O
state	O
data	O
.	O
</s>
<s>
Additional	O
features	O
are	O
available	O
as	O
plugins	B-Application
.	O
</s>
<s>
Plugins	B-Application
are	O
available	O
for	O
network	O
and	O
molecular	O
profiling	O
analyses	O
,	O
new	O
layouts	O
,	O
additional	O
file	O
format	O
support	O
and	O
connection	O
with	O
databases	O
and	O
searching	O
in	O
large	O
networks	O
.	O
</s>
<s>
Plugins	B-Application
may	O
be	O
developed	O
using	O
the	O
Cytoscape	B-Language
open	O
Java	B-Language
software	O
architecture	O
by	O
anyone	O
and	O
plugin	B-Application
community	O
development	O
is	O
encouraged	O
.	O
</s>
<s>
Cytoscape	B-Language
also	O
has	O
a	O
JavaScript-centric	O
sister	O
project	O
named	O
that	O
can	O
be	O
used	O
to	O
analyse	O
and	O
visualise	O
graphs	O
in	O
JavaScript	B-Language
environments	O
,	O
like	O
a	O
browser	O
.	O
</s>
<s>
Cytoscape	B-Language
was	O
originally	O
created	O
at	O
the	O
Institute	O
of	O
Systems	O
Biology	O
in	O
Seattle	O
in	O
2002	O
.	O
</s>
<s>
Now	O
,	O
it	O
is	O
developed	O
by	O
an	O
international	O
consortium	O
of	O
open	B-Application
source	I-Application
developers	O
.	O
</s>
<s>
Cytoscape	B-Language
was	O
initially	O
made	O
public	O
in	O
July	O
,	O
2002	O
(	O
v0.8	O
)	O
;	O
the	O
second	O
release	O
(	O
v0.9	O
)	O
was	O
in	O
November	O
,	O
2002	O
,	O
and	O
v1.0	O
was	O
released	O
in	O
March	O
2003	O
.	O
</s>
<s>
Version	O
2.0	O
was	O
initially	O
released	O
in	O
2004	O
;	O
Cytoscape	B-Language
2.83	O
,	O
the	O
final	O
2.xx	O
version	O
,	O
was	O
released	O
in	O
May	O
2012	O
.	O
</s>
<s>
The	O
Cytoscape	B-Language
core	O
developer	O
team	O
continues	O
to	O
work	O
on	O
this	O
project	O
and	O
released	O
Cytoscape	B-Language
3.0	O
in	O
2013	O
.	O
</s>
<s>
This	O
represented	O
a	O
major	O
change	O
in	O
the	O
Cytoscape	B-Language
architecture	O
;	O
it	O
is	O
a	O
more	O
modularized	O
,	O
expandable	O
and	O
maintainable	O
version	O
of	O
the	O
software	O
.	O
</s>
<s>
While	O
Cytoscape	B-Language
is	O
most	O
commonly	O
used	O
for	O
biological	O
research	O
applications	O
,	O
it	O
is	O
agnostic	O
in	O
terms	O
of	O
usage	O
.	O
</s>
<s>
Cytoscape	B-Language
can	O
visualize	O
and	O
analyze	O
network	O
graphs	O
of	O
any	O
kind	O
involving	O
nodes	O
and	O
edges	O
(	O
e.g.	O
,	O
social	O
networks	O
)	O
.	O
</s>
<s>
A	O
vital	O
aspect	O
of	O
the	O
software	O
architecture	O
of	O
Cytoscape	B-Language
is	O
the	O
use	O
of	O
plugins	B-Application
for	O
specialized	O
features	O
.	O
</s>
<s>
Plugins	B-Application
are	O
developed	O
by	O
core	O
developers	O
and	O
the	O
greater	O
user	O
community	O
.	O
</s>
