<s>
Connectograms	B-Algorithm
are	O
graphical	O
representations	O
of	O
connectomics	O
,	O
the	O
field	O
of	O
study	O
dedicated	O
to	O
mapping	O
and	O
interpreting	O
all	O
of	O
the	O
white	O
matter	O
fiber	O
connections	O
in	O
the	O
human	O
brain	O
.	O
</s>
<s>
These	O
circular	O
graphs	O
based	O
on	O
diffusion	B-Algorithm
MRI	I-Algorithm
data	O
utilize	O
graph	O
theory	O
to	O
demonstrate	O
the	O
white	O
matter	O
connections	O
and	O
cortical	O
characteristics	O
for	O
single	O
structures	O
,	O
single	O
subjects	O
,	O
or	O
populations	O
.	O
</s>
<s>
The	O
connectogram	B-Algorithm
,	O
as	O
a	O
graphical	O
representation	O
of	O
brain	O
connectomics	O
,	O
was	O
proposed	O
in	O
2012	O
.	O
</s>
<s>
Connectograms	B-Algorithm
were	O
also	O
cited	O
as	O
a	O
source	O
of	O
inspiration	O
for	O
the	O
heads-up	O
display	O
style	O
of	O
Tony	O
Stark	O
's	O
helmet	O
in	O
Iron	B-Application
Man	I-Application
3	I-Application
.	O
</s>
<s>
Connectograms	B-Algorithm
are	O
circular	O
,	O
with	O
the	O
left	O
half	O
depicting	O
the	O
left	O
hemisphere	O
and	O
the	O
right	O
half	O
depicting	O
the	O
right	O
hemisphere	O
.	O
</s>
<s>
The	O
fractional	B-Algorithm
anisotropy	I-Algorithm
of	O
each	O
connection	O
is	O
reflected	O
in	O
its	O
color	O
.	O
</s>
<s>
The	O
connectogram	B-Algorithm
can	O
display	O
83	O
cortical	O
regions	O
within	O
each	O
hemisphere	O
,	O
and	O
visually	O
display	O
which	O
areas	O
are	O
structurally	O
connected	O
,	O
all	O
on	O
a	O
flat	O
surface	O
.	O
</s>
<s>
The	O
graphs	O
were	O
originally	O
developed	O
using	O
the	O
visualization	O
tool	O
called	O
Circos	B-Application
,	O
.	O
</s>
<s>
On	O
an	O
individual	O
level	O
,	O
connectograms	B-Algorithm
can	O
be	O
used	O
to	O
inform	O
the	O
treatment	O
of	O
patients	O
with	O
neuroanatomical	O
abnormalities	O
.	O
</s>
<s>
Connectograms	B-Algorithm
have	O
been	O
used	O
to	O
monitor	O
the	O
progression	O
of	O
neurological	O
recovery	O
of	O
patients	O
who	O
suffered	O
a	O
traumatic	O
brain	O
injury	O
(	O
TBI	O
)	O
.	O
</s>
<s>
They	O
have	O
also	O
been	O
applied	O
to	O
famous	O
patient	O
Phineas	O
Gage	O
,	O
to	O
estimate	O
damage	O
to	O
his	O
neural	B-Architecture
network	I-Architecture
(	O
as	O
well	O
as	O
the	O
damage	O
at	O
the	O
cortical	O
levelthe	O
primary	O
focus	O
of	O
earlier	O
studies	O
on	O
Gage	O
)	O
.	O
</s>
<s>
Connectograms	B-Algorithm
can	O
represent	O
the	O
averages	O
of	O
cortical	O
metrics	O
(	O
grey	O
matter	O
volume	O
,	O
surface	O
area	O
,	O
cortical	O
thickness	O
,	O
curvature	O
,	O
and	O
degree	O
of	O
connectivity	O
)	O
,	O
as	O
well	O
as	O
tractography	B-Algorithm
data	O
,	O
such	O
as	O
the	O
average	O
densities	O
and	O
fractional	B-Algorithm
anisotropy	I-Algorithm
of	O
the	O
connections	O
,	O
across	O
populations	O
of	O
any	O
size	O
.	O
</s>
<s>
There	O
are	O
many	O
possibilities	O
for	O
which	O
measures	O
are	O
included	O
in	O
the	O
rings	O
of	O
a	O
connectogram	B-Algorithm
.	O
</s>
<s>
Irimia	O
and	O
Van	O
Horn	O
(	O
2012	O
)	O
have	O
published	O
connectograms	B-Algorithm
which	O
examine	O
the	O
correlative	O
relationships	O
between	O
regions	O
and	O
uses	O
the	O
figures	O
to	O
compare	O
the	O
approaches	O
of	O
graph	O
theory	O
and	O
connectomics	O
.	O
</s>
<s>
Others	O
include	O
additional	O
measures	O
relating	O
to	O
neural	B-Architecture
networks	I-Architecture
,	O
which	O
can	O
be	O
added	O
as	O
additional	O
rings	O
to	O
the	O
inside	O
to	O
show	O
metrics	O
of	O
graph	O
theory	O
,	O
as	O
in	O
the	O
extended	O
connectogram	B-Algorithm
here	O
:	O
</s>
