<s>
Central	B-Algorithm
chemoreceptors	I-Algorithm
of	O
the	O
central	O
nervous	O
system	O
,	O
located	O
on	O
the	O
ventrolateral	O
medullary	O
surface	O
in	O
the	O
vicinity	O
of	O
the	O
exit	O
of	O
the	O
9th	O
and	O
10th	O
cranial	O
nerves	O
,	O
are	O
sensitive	O
to	O
the	O
pH	O
of	O
their	O
environment	O
.	O
</s>
<s>
However	O
,	O
a	O
change	O
in	O
plasma	O
pH	O
alone	O
will	O
not	O
stimulate	O
central	B-Algorithm
chemoreceptors	I-Algorithm
as	O
are	O
not	O
able	O
to	O
diffuse	O
across	O
the	O
blood	O
–	O
brain	O
barrier	O
into	O
the	O
CSF	O
.	O
</s>
<s>
Central	O
chemoreception	O
remains	O
,	O
in	O
this	O
way	O
,	O
distinct	O
from	O
peripheral	B-Algorithm
chemoreceptors	I-Algorithm
.	O
</s>
<s>
Peripheral	B-Algorithm
chemoreceptors	I-Algorithm
(	O
carotid	O
and	O
aortic	O
bodies	O
)	O
and	O
central	B-Algorithm
chemoreceptors	I-Algorithm
(	O
medullary	O
neurons	O
)	O
primarily	O
function	O
to	O
regulate	O
respiratory	O
activity	O
.	O
</s>
