<s>
The	O
cardiac	B-Algorithm
transient	I-Algorithm
outward	I-Algorithm
potassium	I-Algorithm
current	I-Algorithm
(	O
referred	O
to	O
as	O
Ito1	O
or	O
Ito	O
)	O
is	O
one	O
of	O
the	O
ion	O
currents	O
across	O
the	O
cell	O
membrane	O
of	O
heart	O
muscle	O
cells	O
.	O
</s>
<s>
There	O
is	O
correlation	O
between	O
decreased	O
Ito1	O
density	O
and	O
atrial	B-Application
fibrillation	I-Application
.	O
</s>
<s>
This	O
mechanisms	O
may	O
be	O
one	O
of	O
the	O
reasons	O
for	O
the	O
observation	O
that	O
both	O
bradycardia	O
and	O
atrial	B-Application
fibrillation	I-Application
are	O
common	O
in	O
hypothyroidism	O
.	O
</s>
