<s>
Caisis	B-Application
is	O
an	O
open-source	B-Application
,	O
web-based	O
,	O
patient	O
data	O
management	O
system	O
that	O
integrates	O
research	O
with	O
patient	O
care	O
.	O
</s>
<s>
Caisis	B-Application
was	O
designed	O
around	O
structured	O
chronological	O
patient	O
histories	O
which	O
could	O
be	O
displayed	O
to	O
clinicians	O
and	O
processed	O
by	O
computer	O
algorithms	O
.	O
</s>
<s>
It	O
is	O
released	O
under	O
the	O
GNU	B-License
General	I-License
Public	I-License
License	I-License
(	O
GPL	B-License
)	O
and	O
is	O
entirely	O
web	O
based	O
;	O
written	O
mainly	O
in	O
C#	B-Application
,	O
HTML	B-Language
,	O
and	O
JavaScript	B-Language
it	O
runs	O
on	O
the	O
.Net	B-Application
Framework	I-Application
.	O
</s>
<s>
Caisis	B-Application
has	O
been	O
developed	O
to	O
allow	O
the	O
system	O
to	O
evolve	O
and	O
adapt	O
to	O
the	O
evolving	O
landscape	O
of	O
clinical	O
research	O
.	O
</s>
<s>
As	O
a	O
framework	O
,	O
it	O
is	O
easy	O
for	O
developers	O
to	O
extend	O
Caisis	B-Application
by	O
adding	O
new	O
fields	O
and	O
tables	O
,	O
plugin	O
features	O
,	O
and	O
new	O
modules	O
with	O
standalone	O
functionality	O
.	O
</s>
<s>
goal	O
of	O
Caisis	B-Application
:	O
to	O
capture	O
the	O
patient	O
's	O
clinical	O
"	O
story	O
"	O
.	O
</s>
<s>
Capturing	O
data	O
in	O
the	O
structured	O
,	O
Caisis	B-Application
relational	O
data	O
model	O
,	O
will	O
facilitate	O
the	O
generation	O
of	O
large	O
clean	O
datasets	O
for	O
multi-institution	O
collaborative	O
research	O
.	O
</s>
