<s>
The	O
Berendsen	B-Algorithm
thermostat	I-Algorithm
is	O
an	O
algorithm	O
to	O
re-scale	O
the	O
velocities	O
of	O
particles	O
in	O
molecular	O
dynamics	O
simulations	O
to	O
control	O
the	O
simulation	O
temperature	O
.	O
</s>
<s>
In	O
many	O
instances	O
,	O
systems	O
are	O
initially	O
equilibrated	O
using	O
the	O
Berendsen	O
scheme	O
,	O
while	O
properties	O
are	O
calculated	O
using	O
the	O
widely	O
known	O
Nosé	B-Algorithm
–	I-Algorithm
Hoover	I-Algorithm
thermostat	I-Algorithm
,	O
which	O
correctly	O
generates	O
trajectories	O
consistent	O
with	O
a	O
canonical	O
ensemble	O
.	O
</s>
<s>
However	O
,	O
the	O
Berendsen	B-Algorithm
thermostat	I-Algorithm
can	O
result	O
in	O
the	O
flying	O
ice	O
cube	O
effect	O
,	O
an	O
artifact	O
which	O
can	O
be	O
eliminated	O
by	O
using	O
the	O
more	O
rigorous	O
Bussi	O
–	O
Donadio	O
–	O
Parrinello	O
thermostat	O
;	O
for	O
this	O
reason	O
,	O
it	O
has	O
been	O
recommended	O
that	O
usage	O
of	O
the	O
Berendsen	B-Algorithm
thermostat	I-Algorithm
be	O
discontinued	O
in	O
almost	O
all	O
cases	O
except	O
for	O
replication	O
of	O
prior	O
studies	O
.	O
</s>
