In the graphic below I have extracted a table from a very old study. It highlights the huge increase in lipofuscin aggregation with age. They used acetyl l carnitine has a therapeutic intervention and the results were quite good but only at very high dosages. Other and much more recent research has found that acetyl l carnitine can also play an important role in preventing Age Related Macular Degeneration (AMD). In those studies they created a compound called Phototrop, a combination of acetyl L carnitine, omega 3 fatty acids, and co-enzyme Q10.
Word of warning: you should always use alpha lipoic acid with ALC because ALC increases mitochondrial function and mitochondria are the key region where oxidants are formed.
The table below is from