T D Heiman Patterson
Affiliation: Drexel University
- Background and gender effects on survival in the TgN(SOD1-G93A)1Gur mouse model of ALST D Heiman-Patterson
Department of Neurology, Drexel University College of Medicine, Mail Stop 423, 245 North 15th Street, Philadelphia, PA 19102, USA
J Neurol Sci 236:1-7. 2005..This is the first report of a shortened lifespan when the G93A SOD1 transgene is placed on the SJL/J background and an increased survival with the loss of gender influences when the transgene is placed on the C57BL/6J background...
- Elevated cortical extracellular fluid glutamate in transgenic mice expressing human mutant (G93A) Cu/Zn superoxide dismutaseG M Alexander
Department of Neurology, MCP Hahnemann University, Philadelphia, Pennsylvania 19102 1192, USA
J Neurochem 74:1666-73. 2000....
- The ALSSQOL: balancing physical and nonphysical factors in assessing quality of life in ALSZ Simmons
Department of Neurology, Penn State College of Medicine, Hershey, PA 17033, USA
Neurology 67:1659-64. 2006..Current instruments are either too heavily weighted toward strength and physical function or useful for the evaluation of individuals but of less utility in assessing large samples...
- A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosisM E Cudkowicz
Neurology Clinical Trials Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Neurology 61:456-64. 2003..To determine if long-term topiramate therapy is safe and slows disease progression in patients with ALS...