Working with an ethnically diverse patient population, Einstein-Montefiore cardiology investigators conduct a wide range of basic science and clinical research to achieve 3 missions:
- Prevent the development of cardiovascular disease
- Successfully treat patients with heart disease, including the most critical, advanced cases
- Provide patients with the most accessible, informed healthcare experience possible
Cardiac Disease Prevention Studies
Cardiovascular disease is the leading cause of death for both men and women. Einstein-Montefiore researchers are studying innovative approaches to promote exercise, a healthy diet, weight loss, and the potential effects of statins in order to help patients adopt a heart-healthy lifestyle.
Heart Failure and Transplantation Studies
Einstein-Montefiore investigators are studying cutting-edge techniques to save the most critically diseased hearts, the benefit of stimulating the patient’s own stem cells and cardiac tissue to help the heart recover, and innovative high-altitude athletic training methods and muscle-building drugs to help patients with heart failure become stronger.
Interventional Cardiology Studies
Investigations in thrombolysis in myocardial infarction (TIMI), nitric oxide for MI treatment during angioplasty, Periscope trial, bypass angioplasty revascularization investigation 2 diabetes (BARI 2D), effectiveness of glycoprotein IIb/IIIa inhibitor use during primary coronary angioplasty, percutaneous coronary interventions (PCI) registry, racial and ethnic factors in response to treatment, vascular imaging technologies, emergency angioplasty, treatment devices, pharmacological treatment for MI, novel predictors of atherosclerosis for optimal patient care.
Myocardial Blood Flow
There is currently no blood test in clinical use to detect myocardial ischemia (decreased blood flow to the heart muscle), often a precursor of heart attack. Einstein-Montefiore Heart Center investigators are studying a novel blood test that may improve the ability to diagnose and treat mycardial ischemia.
Medical Education Studies
Investigators are conducting studies to achieve excellence in training medical students, residents, and fellows through focused cardiovascular physical exam curriculum and an intensive pre-fellowship orientation program.
Cell Death and Cardiovascular Disease
The Kitsis laboratory studies fundamental mechanisms of cell death and their role in cardiovascular disease.
Ion Channel Function
The McDonald laboratory studies the role of ion channel function in normal and disease states.
The Sibinga laboratory uses genetic approaches to study vascular remodeling, a complex biological response to changes in hemodynamics, metabolism, local and systemic inflammation, and physical injury.