CHEM& 262 Organic Chemistry II • 6 Cr.
Second in a three-course organic chemistry sequence. Format includes laboratory work. Prerequisite: CHEM& 261.
After completing this class, students should be able to:
- Interpret patterns of reactivity for reactions of alkenes, alkynes, alkyl halides, alcohols, ethers, epoxides, radicals, and aromatic compounds, and provide electron–pushing mechanisms and multistep products where applicable.
- Apply IUPAC nomenclature rules and predict trends in physical properties for simple organic molecules based on their functional groups.
- Provide reagents or predict products for reactions of carbon nucleophiles, such as Grignard and Gilman reagents.
- Predict the relative energies of radicals and product distributions which arise from radical reactions, including an understanding of side reactions which occur.
- Apply resonance and/or molecular orbital theory in determining the stability of conjugated systems and predicting the product of conjugate addition reactions (1, 2- and 1,4-conjugate additions, cycloadditions, etc.)
- Design syntheses of organic molecules of moderate complexity using multiple synthetic steps to produce the highest yield using the fewest steps and/or protecting groups.
- Deduce molecular structures based on various spectroscopic techniques such as NMR, MS, IR, and/or UV-Vis.
- Effectively use laboratory techniques to synthesize, isolate, and purify samples, and assess the purity and yield of final products.