|Executive Summary:||The NanoCycler™ genotyping device and accompanying disposables (polymer chips) has been designed to handle and process patient sample material directly from e.g. mouth rinse or saliva swab - and provide a result within 15 minutes.
The platform is a fully-integrated system, incorporating all necessary “laboratory” steps to perform SNP genotyping;
• Human DNA material is collected from a mouth rinse or saliva swab,
• The sample is applied to a disposable polymer chip and
• The chip is inserted into the NanoCycler™ device which in turn provides the answer to whether a given SNP is present or absent.
The NanoCycler™ device is small in size and “footprint”; contains no moving parts and does not require any external pumping or suction to enable the on-chip flow control or sample preparation; the polymer chip as well as the device consist of established components designed with a particular focus on low cost and scalability. Moreover, the processes utilised in the NanoCycler™ device and the polymer chip is extremely versatile - offering significant expansion opportunities of the addressable application range.|