Sean Klepper M.D.
Artur Zembowicz M.D....
- Seen on the hands and feet (where it can result in permanent loss of the nail) and mucosal membranes of the mouth or genitalia
- Risk of squamous cell carcinoma in chronic lesions
- Rare associations include Castleman disease, chronic hydroxyurea therapy and hepatitis C.
- Epidermal ulceration, with the typical changes of lichen planus at the edges of the ulcers
- Plasma cells are universally present in lesions of mucosal membranes.