NCI is at the forefront of research into how doctors diagnose and treat various types of cancer, as well as what advances are being made. The following pages highlight information you should know about six of the most common cancers and some of the NCI funded research currently under way. (In future issues, NIH MedlinePlus will feature research about additional forms of cancer.)
Lung cancer causes more deaths than the next three most common cancers combined (colon, breast, and prostate). In 2007, scientists estimate that more than 213,000 people will be newly diagnosed with lung cancer, and over 160,000 people will die of the disease. Since 87 percent of lung cancers are caused by smoking, preventing people from starting to smoke and increasing the quit rate are important approaches.
Screening and Diagnosis
There are two main types of lung cancer: Non-small cell lung cancer (NSCLC) is the more common type; small cell lung cancer (SCLC) makes up about 20 percent of all lung cancer cases.
Your doctor will perform a physical exam and ask questions about your medical history. She will ask if you smoke, and, if so, how long you have smoked. When listening to your chest with a stethoscope, your doctor can sometimes hear fluid around the lungs, which could (but doesn't always) suggest cancer. You may receive chest X-rays and possibly other chest scans. In some cases, your doctor may need to remove a piece of tissue from your lungs for examination under a microscope. This is called a biopsy.
Your symptoms may include a persistent cough, lingering bronchitis, and even coughing up blood. If lung cancer has advanced beyond the early stages and even spread (metastasized) beyond the lungs, symptoms may include weight loss, fatigue, difficulty breathing, and more severe reactions.
Surgery, chemotherapy, and radiation therapy are the most common forms of treatment for lung cancer. Surgery is used to cut out the entire lung or the part of the lung where the cancer is before it can spread. Chemotherapy, sometimes referred to as "chemo," is the use of strong drugs to treat cancer. There are more than 100 different chemo drugs used today to kill cancer or to slow its growth. Radiation therapy uses special equipment to send high doses of radiation to the cancer cells to kill them. Sometimes, your doctor will use surgery, chemo, and radiation therapy in combination.