External Ids for H1FX Gene
Previous GeneCards Identifiers for H1FX Gene
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H1 family. [provided by RefSeq, Oct 2015]
GeneCards Summary for H1FX Gene
H1FX (H1 Histone Family, Member X) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and E2F mediated regulation of DNA replication. GO annotations related to this gene include poly(A) RNA binding.
UniProtKB/Swiss-Prot for H1FX Gene
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures