Current Research and Scholarly Interests
1. Translating advances in genomics for patient care. Currently we are using next generation sequencing approaches to characterize the clonal population in T or B cell cancers,
how theses cells reconstitute following transplantation, and their role in disease progression and complications such as graft-versus-host disease.
2.Using traditional and next generation genomic approaches to characterize the molecular basis of myeloproliferative neoplasms
3. Molecular basis of pediatric immune thrombocytopenia - underlying etiology, what differentiates the 80% who spontaneously remit form those who develop chronic disease, identification of molecular biomarkers predicting response to thrombopoietin agonists
4. Whole genome studies of families with interesting pedigrees - inherited thrombocytopenia, thrombosis following exposure to oral contraceptives