Garyfalia I Drossopoulou
Affiliation: NCSR Demokritos
- Impaired transcription factor interplay in addition to advanced glycation end products suppress podocalyxin expression in high glucose-treated human podocytesGaryfalia I Drossopoulou
Institute of Biology, National Centre for Scientific Research Demokritos, Terma Patriarchou Grigoriou and Neapoleos Str, 15310 Agia Paraskevi, Attiki, Greece
Am J Physiol Renal Physiol 297:F594-603. 2009....
- Glucose-induced gradual phenotypic modulation of cultured human glomerular epithelial cells may be independent of Wilms' tumor 1 (WT1)Nikolaos E Tsotakos
Institute of Biosciences and Applications, National Centre for Scientific Research Demokritos, Athens, Greece
BMC Cell Biol 14:28. 2013..We used an in vitro model of human glomerular epithelial cells (HGEC) to investigate the role of high glucose in dysregulating the podocytic epithelial phenotype and determined the time needed for this change to occur...
- Synthesis of a folate functionalized PEGylated poly(propylene imine) dendrimer as prospective targeted drug delivery systemZili Sideratou
Institute of Physical Chemistry, NCSR Demokritos, 15310 Aghia Paraskevi, Attiki, Greece
Bioorg Med Chem Lett 20:6513-7. 2010..These properties coupled with specificity towards the folate receptor and the low toxicity render folate functionalized PEGylated poly(propylene imine) dendrimer promising candidate for targeted drug delivery...
- High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cellsPanagiotis D Venieratos
Institute of Biology, National Centre for Scientific Research Demokritos, Athens, Attiki, Greece
Cell Signal 22:791-800. 2010..These results indicated that glucose-induced endogenous IL-1beta expression increased betaTC-6 cells apoptosis by inhibiting, at least in part, IRS-2/Akt-mediated signalling through SOCS-1 upregulation...