Product Sector: Medical → Therapeutics → Bone Graft
Fluidinova is a specialized manufacturer of synthetic nanocrystalline hydroxyapatite material, which is commercialized under the brand name nanoXIM®. Using an innovative proprietary technology - NETmix® - Fluidinova produces a highly pure, single phase nanoHydroxyapatite. nanoXIM® is supplied worldwide in different forms to manufacture Medical Devices, for Personal Care Product formulations, R&D activities and many other applications.
Fluidinova produces highly pure nanocrystals of hydroxyapatite, both in water based pastes and spray dried aggregated micron-size powders.
These nanoXIM•HAp products are suitable for innumerous applications, namely as polymers or other materials functionalization, separation/purifications processes, drug delivery and many others applications and R&D activities.
Fluidinova produces high quality hydroxyapatite nanoparticles as a raw-material for medical devices applications. The nanoXIM•HAp products present high purity, single-phase, nanocrystalline features and are in compliance with the ISO13779 and ASTM F1185 standards requests for medical applications regarding heavy metals and other specifications.
High Resolution Transmission Electronic Microscopy (HRTEM) analysis reveals that nanoXIM•HAp products are highly nanocrystalline, presenting the nanocrystals in a structure perfectly aligned.
Other main characteristics of the nanoXIM•HAp material are the high specific surface BET area (> 100 m2/g) and the precise stoichiometry of Calcium/Phosphate ions resulting in a Ca/P ratio always near to 1.67. The high consistency level of these materials results in a strongly feasible product for medical applications.
Research has demonstrated the advantages of using nanostructured nanoXIM hydroxyapatite in bone scaffolds substitutes and also the influence of the hydroxyapatite crystal size on proteins adsorption and osteoblast adhesion.
Further information can be found in Laranjeira et al (2010) and Ribeiro et al (2010).