Do animal models help predict host responses to fungal infections and antifungal treatments? Choosing therapy on the basis of efficacy not safety
Abstract number: S108
Clinical outcomes from invasive fungal infections involve a complex interplay between the infecting organism, antifungal treatment and the host immune response. Factors such as the host's neutropenic status are well known to influence outcome and may be of particular relevance if the antifungal treatment is fungistatic rather than fungicidal, but the immune response involves far more than neutrophils alone. Cytokine changes may correlate with both clinical response and clinical failure. In this symposium the faculty will show how changes in vitro may correlate with responses in vivo in animal models and therefore predict the response in the human host.
|Session name:||Abstracts 20th European Congress of Clinical Microbiology and Infectious Diseases|
|Location:||Vienna, Austria, 10 - 13 April 2010|
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