Willerman et al. (1991) conducted their study at a large southwestern university. They selected a sample of 40 right-handed Anglo introductory psychology students who had indicated no history of alcoholism, unconsciousness, brain damage, epilepsy, or heart disease. These subjects were drawn from a larger pool of introductory psychology students with total Scholastic Aptitude Test Scores higher than 1350 or lower than 940 who had agreed to satisfy a course requirement by allowing the administration of four subtests (Vocabulary, Similarities, Block Design, and Picture Completion) of the Wechsler (1981) Adult Intelligence Scale-Revised. With prior approval of the University's research review board, students selected for MRI were required to obtain prorated full-scale IQs of greater than 130 or less than 103, and were equally divided by sex and IQ classification.
The MRI Scans were performed at the same facility for all 40 subjects. The scans consisted of 18 horizontal MR images. The computer counted all pixels with non-zero gray scale in each of the 18 images and the total count served as an index for brain size.
A straightforward method for evaluating the relationship between brain size and IQ scores is the correllation coefficient. For the 20 men in the study, the researchers report correlations between IQ scores and brain sizes before and after controlling for body size of r = 0.51 (p-value less than 0.05) and r = 0.65 (p-value less than 0.01) respectively. For the 20 women in the study, the researchers report the corresponding correlations to be r = 0.33 (p-value not significant) and r = 0.35 (p-value not significant). With both genders pooled the correlation between IQ and adjusted brain size was r = 0.51 (p-value less than 0.05).