TNM 7 Classification
TNM 6 Classification
1. Rules for Classification
The classification applies to carcinomas. Papilloma is excluded. There should be histological or cytological confirmation of the disease.
The following are the procedures for assessing T, N, and M categories:
T categories. Physical examination, imaging, and endoscopy
N categories. Physical examination and imaging
M categories. Physical examination and imaging
2. Regional Lymph NodesThe regional lymph nodes are the nodes of the true pelvis, which essentially are the pelvic nodes below the bifurcation of the common iliac arteries. Laterality does not affect the N classification.
3. TNM Clinical Classification3.1. T - Primary Tumour
The suffix (m) should be added to the appropriate T category to indicate multiple tumours. The suffix (is) may be added to any T to indicate presence of associated carcinoma in situ.
TX. Primary tumour cannot be assessed
T0. No evidence of primary tumour
Ta. Noninvasive papillary carcinoma
Tis. Carcinoma in situ: "flat tumour"
T1. Tumour invades subepithelial connective tissue
T2. Tumour invades muscle
T2a. Tumour invades superficial muscle (inner half)
T2b. Tumour invades deep muscle (outer half)
T3. Tumour invades perivesical tissue:
T3b. macroscopically (extravesical mass)
T4. Tumour invades any of the following: prostate, uterus, vagina, pelvic wall, abdominal wall
T4a. Tumour invades prostate, uterus, or vagina
T4b. Tumour invades pelvic wall or abdominal wall
3.2. N - Regional Lymph Nodes
NX. Regional lymph nodes cannot be assessed
N0. No regional lymph node metastasis
N1. Metastasis in a single lymph node 2 cm or less in greatest dimension
N2. Metastasis in a single lymph node more than 2 cm but not more than 5 cm in greatest dimension, or multiple lymph nodes, none more than 5 cm in greatest dimension
N3. Metastasis in a lymph node more than 5 cm in greatest dimension
3.3. M - Distant Metastasis
MX. Distant metastasis cannot be assessed
M0. No distant metastasis
M1. Distant metastasis
4. pTNM Pathological ClassificationThe pT, pN, and pM categories correspond to the T, N, and M categories.
5. G Histopathological GradingGX. Grade of differentiation cannot be assessed
G1. Well differentiated
G2. Moderately differentiated
G3-4. Poorly differentiated/undifferentiated
6. Stage Grouping