Jun 10, 2011 - 9:45 pm
very interesting. Cancer cells undergo mutations and develop resistance. That is why metastatic tumors could have variations from primary. Please watch explanation: http://www.medscape.com/viewarticle/741103
Ding L, Ellis MJ, Shunqiang L, et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature. 2010;464:999-1005. Available at: www.medscape.com/medline/abstract/20393555 Accessed April 21, 2011.