|Closed||Acute Lymphoid Leukemia (ALL)||NA||
RATIONALE: Learning about the long-term effects of methotrexate on brain function may help doctors plan cancer treatment.
PURPOSE: This clinical trial is looking at brain function in young patients receiving methotrexate for acute lymphoblastic leukemia.
|Ages Eligible for Study:||1 Year to 17 Years|
|Genders Eligible for Study:||Both|
|Accepts Healthy Volunteers:||No|
- Diagnosis of acute lymphoblastic leukemia
- Enrolled on COG-AALL0434 or COG-AALL0232
- No CNS-3 disease
No known significant neurodevelopmental disability unrelated to cancer diagnosis including, but not limited to, any of the following:
- Down syndrome
- Fragile X mental retardation
- Pervasive developmental disability
- Seizure disorder
- Attention-deficit hyperactivity disorder or specific learning disability (e.g., dyslexia) allowed
- No sensory impairment (e.g., pre-existing uncorrectable vision impairment or deafness)
PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
- No cranial radiation therapy
See this trial at ClinicalTrials.gov
Access protocol and consent forms at Fred Hutchinson Cancer Research Center
- Talk to your health care providers first before making decisions about your health care.
- Whether you are eligible for a research study depends on many things. There are specific requirements to be in research studies. These requirements are different for each study.