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Vasopressor Drugs in Acute Kidney Injury
Pressors; Vasoactive drugs; Vasoconstrictors; Vasopressors
Vasopressor Drug Names
Class and Category
All of these agents are able to increase mean arterial blood pressure.
Most of their actions are based on alpha- and beta-receptor stimulation. However, other less commonly used agents (vasopressin, terlipressin, angiotensin II) work through separate receptors.
Indications, Dosage, Preparation, Contraindications
See individual drug chapters.
Septic shock, systemic inflammation (trauma, major surgery, cardiopulmonary bypass, and the like), or pharmacological vasodilatation (phosphodiesterase inhibitors, sedative drugs, epidural or spinal block) often cause systemic hypotension despite a normal or increased cardiac output. Under these circumstances, hypotension may persist despite volume