Thomas E Coyle
Affiliation: SUNY Upstate Medical University
- Acute leukemia associated with valproic acid treatment: a novel mechanism for leukemogenesis?Thomas E Coyle
Department of Medicine, SUNY Upstate Medical University, Syracuse, New York 13210, USA
Am J Hematol 78:256-60. 2005..We propose that valproic acid therapy may lead to secondary leukemia by increasing DNA damage through chronic inhibition of histone deacetylase...