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How is Sustiva usedMultiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system that leads to the degeneration of nerves in the brain and spinal cord. The immune or infection-fighting system in MS patients attacks the body's own cells, causing progressive damage in the brain and spinal cord. Symptoms of MS include vision problems, muscle weakness, trouble walking or speaking, numbness and tingling, problems related to bowel or bladder control, and others. Although MS was first identified over a century ago, a cure still remains to be found. Available therapies help improve patients overall quality of life and minimize long term disability (by reducing inflammation, delaying the progression of the disease, reducing the frequency and severity of acute attacks, and improving walking speed). Physical, occupational, speech, and cognitive therapy also are used for improving function.
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iramate can cause visual changes, including decreased acuity along with eye pain. This may necessitate withdrawal of the drug to prevent permanent visual loss. Decreased sweating and the resultant increase in body temperature, sometimes severe enough to require hospitalization, may occur with iramate. Patients should be monitored for sweat output, especially in hot weather. Side effects of iramate include difficulty concentrating, behavioral changes, and drowsiness.
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