The Nechisti Order was the religious body of the Nechani, whose members devoted their lives to the Ancestral Spirits. They generally kept to their affairs, though they did welcome those who wished to seek the Spirits for themselves.
In 2373, Kes was severely injured by an encounter with a Nechisti shrine. A Nechisti Order monk subsequently served as Kathryn Janeway's guide when she sought to undergo a sacred ritual to save Kes' life. (VOY: "Sacred Ground")