Institute for Medicine and Engineering
University of Pennsylvania
Vagelos Research Labs
3340 Smith Walk
Philadelphia, PA 19104
Tel: 1 (215) 573-5704
M.S. Chemical and Biomolecular Engineering, University of Pennsylvania, 2013.
B.S. Chemical Engineering, Columbia University, 2011.
Detection of platelet sensitivity to antiplatelet therapies using a whole blood microfluidic assay.
Recapitulation of trauma and the fibrinolytic state under flow.
Microfluidic assay of hemophilic blood: Studying contact pathway deficiencies.
Multiscale prediction of patient-specific platelet function under flow over tissue factor and collagen biomimetic surfaces
I study the role of platelets in hemostasis and thrombosis in various microfluidic thrombosis models. Specifically, I examine the effects of various anti-platelet and anti-thrombotic therapies on platelet function under flow. I characterize platelet ligand-receptor dynamics, clot morphology, and the effects of antagonists on secondary platelet aggregation using in vitro microfludic devices capable of recreating platelet biochemical signaling pathways and transport processes in vivo.