Sujit Kumar Mohanty
Affiliation: Cincinnati Children's Hospital Medical Center
- Loss of interleukin-12 modifies the pro-inflammatory response but does not prevent duct obstruction in experimental biliary atresiaSujit Kumar Mohanty
Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
BMC Gastroenterol 6:14. 2006..Based on the role of IL-12 as a key proinflammatory cytokine, we hypothesized that loss of IL-12 prevents the obstruction of extrahepatic bile ducts...
- Th2 signals induce epithelial injury in mice and are compatible with the biliary atresia phenotypeJun Li
Cincinnati Children s Hospital Medical Center and the Department of Pediatrics of the University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
J Clin Invest 121:4244-56. 2011..These findings demonstrate compatibility between Th2 commitment and the pathogenesis of BA, and suggest that patient subgrouping in future clinical trials should account for differences in Th2 status...
- Temporal-spatial activation of apoptosis and epithelial injury in murine experimental biliary atresiaNissa Erickson
Cincinnati Children s Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
Hepatology 47:1567-77. 2008..In vivo, administration of the caspase inhibitor IDN-8050 decreased apoptosis in the duct epithelium and the extent of epithelial injury after RRV challenge...