In the paper:
- Michael Berk et al, So depression is an inflammatory disease, but where does the inflammation come from?, BMC Medicine 2013, 11:200, doi:10.1186/1741-7015-11-200
it is presented as an undisputed fact that depression is an inflammatory disease.
For example (the first sentence of the abstract):
We now know that depression is associated with a chronic, low-grade inflammatory response and activation of cell-mediated immunity, as well as activation of the compensatory anti-inflammatory reflex system.
However, AFAIK, we are far from understanding the etiology of depression (perhaps there is no universal one). Sure, there are many correlates (for example – levels of neurotransmitters), but I haven't heard that there a single, accepted cause (except for the cited paper). For the reference, Wikipedia mentions inflammation as one of multiple related conditions in the "Other hypotheses" section.
So, as of now, is it universally accepted that depression is an inflammatory disease? And if not, is it at least one of many mainstream opinions?
Discussion on HN, through which I've learnt about this paper