OverviewSide Effects and InteractionsTaking the MedicineSpecial Precautions
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| Side Effects and Interactions|
The most common side effects of Evista are hot flashes and leg cramps.
Your doctor should be notified immediately of any of the following symptoms: pain in the calf or groin, sudden shortness of breath or sharp chest pain, sudden severe headache, blurred vision or speech, weakness or numbness in an arm or leg. These might indicate a blood clot requiring prompt medical attention.
Other side effects reported with Evista include migraine headaches, sinusitis, joint pain, insomnia, rash, sweating, digestive upset, vaginitis, and infections.
Evista may alter tests of blood fats, lowering total cholesterol, LDL cholesterol, apolipoprotein B and fibrinogen. It raises values of apolipoprotein A1.
Like estrogen, it may increase the levels of certain thyroid tests without changing thyroid function.
Evista may change prothrombin times modestly if given with Coumadin, so monitoring is important.
Medications such as ibuprofen (Advil, Motrin IB), indomethacin and naproxen (Aleve, Naprosyn) may interact with Evista.
Check with your doctor and pharmacist before taking any other medicine while taking Estrace.