The meeting will begin at 12 noon on July 12 and will conclude around 6 pm on July 13. Breakfast and lunch will be served and a poster session will take place on the afternoon of July 13.
Afternoon of July 12
12:00 – 1:00 Welcome Lunch (Colloquium, 6th floor Ross) / Setup Posters (Blau Lobby)
1:00 – 1:15 Introduction (Blau Auditorium, Ross School of Business)
This session will lay out the charge of the meeting, which is to review the uses of 1000 Genomes and sequencing in genetic studies, but also to have a discussion about the future of community resource sequencing projects.
· Gonçalo Abecasis (University of Michigan)
1:15 – 2:45 Plenary Session I – Advances in the Analysis of Next Generation Data
Presenters will discuss advances in the analysis of next generation sequencing; presenters should discuss current challenges and data resources that might help drive further advances in at least 1-2 slides.
1:15 - 1:45 Eric Banks (Broad Institute of Harvard and MIT)
1:45 - 2:15 Hyun Min Kang (University of Michigan)
2:15 - 2:30 Benjamin Neale (Massachusetts General Hospital)
2:30 - 2:45 Yaniv Erlich (Whitehead Institute)
Population-scale profile of short tandem repeat variations
2:45 – 3:15 Afternoon Snack / Poster Viewing (Blau Lobby)
3:15 – 4:45 Plenary Session II – The Future Of Sequencing Data Generation and Analysis
Presenters will discuss advances in production of next generation sequence data; presenters should discuss how these might influence future community resource projects in 1-2 slides.
3:15 – 3:45 Jay Shendure (University of Washington)
3:45 – 4:15 Yingrui Li (BGI)
Sequencing and Assembly of Genomes on a Large Scale
4:15 – 4:45 Jan Korbel (European Molecular Biology Laboratory)
Beyond SNPs II: Analysis of Structural Variation in the 1000 Genomes Project
4:45 – 5:15 Late Afternoon Snack / Poster Viewing (Blau Lobby)
5:15 – 7:15 Plenary Session III – Insights into Population Genetics From Large Scale Sequencing
Presenters will discuss major insights into human population genetics, and how the next round of large scale sequencing studies may enable further insights in at least 1-2 slides.
5:15 – 5:45 Gil McVean (University of Oxford)
5:45 – 6:15 John Novembre (University of California Los Angeles)
6:15 – 6:45 Molly Przeworski (University of Chicago)
Beyond the Classic Sweep: Insights into Modes of Adaptation from Genomic Variation Data
6:45 – 7:00 Michael DeGiorgio (University of California, Berkeley)
7:00 – 7:15 Alexander Platt (University of California, Los Angeles)
7:15 Dinner on Your Own
Morning of July 13
7:30 – 8:00 Breakfast (Blau Lobby)
8:00 – 9:45 Plenary Session IV – Studying Human Disease by Genotyping, Imputation and Sequencing
This session will provide examples of contrasting designs for human genetic studies, ranging from case-control studies, to population studies, to studies of founder populations and studies informed by electronic medical records. Presenters are invited to discuss what sort of community resources might be most informative for their ongoing and future genetic studies in at least 1-2 slides.
8:00 – 8:30 Sekar Kathiresan (Massachusetts General Hospital)
8:30 – 9:00 Augustine Kong (deCode Genetics)
Small is Beautiful: Genetic Studies in the Founder Population of Iceland
9:00 – 9:30 Dan Roden (Vanderbilt University)
9:30 – 9:45 Andrew Wood (Peninsula Medical School)
1000 Genomes Imputation Identifies Low-Frequency, Large Effect Biomarker Associations
9:45 – 10:15 Morning Break / Poster Viewing (Blau Lobby)
10:15 – 12:00 Plenary Session V – The Evolution of Human Complex Trait Studies
This session will review the evolution of human gene mapping studies for several traits, starting with the era prior to genomewide association studies and ending with examples of current studies informed by 1000 Genomes data and other large scale sequencing efforts. Presenters are invited to discuss what sort of community resources might be most informative for their ongoing and future genetic studies in at least 1-2 slides.
10:15 – 10:45 Ines Barroso (Wellcome Trust Sanger Institute)
Large Scale Genetic Studies in European Populations
10:45 – 11:15 Michael Boehnke (University of Michigan)
11:15 – 11:45 Judy Cho (Yale University)
11:45 – 12:00 Carlo Sidore (University of Michigan)
Afternoon of July 13
12:00 – 1:00 Lunch (Colloquium, 6th floor Ross) / Poster Viewing (Blau Lobby)
1:00 – 2:45 Plenary Session VI – The Future is Now: Large Scale Sequencing in Human Disease
This session will review highlights from some of the most informative large scale sequencing studies, with discussion of directions for future studies and how they might be informed (and inform) the design of community resource projects.
1:00 – 1:30 Debbie Nickerson (University of Washington)
Learning about Human Disease Through Exome Sequencing: Examples and Challenges
1:30 – 2:00 Shaun Purcell (Mount Sinai School of Medicine)
Genetics to Study Human Psychiatric Traits
2:00 – 2:30 Cisca Wijmenga (University of Groningen)
2:30 – 2:45 Jeroen Van Rooij (Erasmus Medical Center)
2:45 – 3:45 Poster Session (Blau Lobby)
3:45 – 5:45 Plenary Session VII – The Future of Large Scale Sequencing Studies
This session will discuss ideas for the future of community resource sequencing studies, designed to inform human genetics. Presenters can discuss their own ongoing gene mapping studies but are invited to spend a substantial fraction of their time discussing possibilities for the future, informed by discussions in earlier sessions.
3:45 – 4:15 Richard Durbin (Wellcome Trust Sanger Institute)
Advances in Genome Assembly and Analysis: What Is Needed?
4:15 – 4:45 Gonçalo Abecasis (University of Michigan)
4:45 – 5:15 Andrew Clark (Cornell University)
Maximizing Insights into Human Evolution and Biology
5:15 – 5:45 Nancy Cox (University of Chicago)
5:45 – 6:15 Closing Discussion
An archive of meeting tweets is available here: