Irofol is different than your typical iron containing pharmaceutical products. It contanins 150 mg of elemental iron, as a polysaccharide-iron complex. This special form of iron is well absorbed and well tolerated. Irofol is effective, cost-efficient and has a once-a-day dosing regimen in the majority of the cases. Most iron preparations have some form of ionized ferric of ferrous iron in them thatcmes into contact with the stomach and upper gastrointestinal tract. Typically, this contact leads to side effects such as: upser stomach epigastric pain, constipation or diarrhea. The PIC in irofol is an ionized iron delivery system that allows the ionic iron to be delivered to the bloodstream, without coming into contact with the stomach or upper GI tract. The PIC irofol is absorbed intact through the small intestine where it is them delivered to the bloodstream. Once free from the PIC, the ionized iron can be used by the body to make hemoglobin.