Melting computes, for a nucleic acid duplex, the enthalpy and entropy of the helix-coil transition, and then its melting temperatures. Three types of hybridisation are possible: DNA/DNA, DNA/RNA, and RNA/RNA. The program uses the method of nearest-neighbors. The set of thermodynamic parameters can easily be changed, for instance following an experimental breakthrough.
DocumentationUser manual included and available in HTML format from http://www.ebi.ac.uk/compneur-srv/melting/melting5-doc/melting.html
This is a GNU package:melting
released on 2 November 2011
|License||Verified by||Verified on||Notes|
|GPLv2orlater||Andrew Engelbrecht||31 January 2001|
Leaders and contributors
|Nicolas Le Novere||Maintainer|
Resources and communication
This entry (in part or in whole) was last reviewed on 22 June 2012.