Periosteal osteosarcoma are more rare than conventional or parosteal osteosarcoma and arises from the surface of the bone, most commonly in diaphyses of femur and tibia. Age of presentation is typically 10-20 years of age. Scalloping of the adjacent cortex is common and there are often spicules of bone emanating from the lesion in a sunburst pattern. Also seen commonly is periosteal reaction. Intramedullary invasion and extension is uncommon. MRI signal is typically not helpful (low T1 and high T2.) Spicules of bone emanating in sunburst pattern tend to be low T2 in signal. Differential includes juxtacortical chondroma and high-grade surface osteosarcoma.
- Osteosarcoma by Todd Kooy, M.D., University of Washington Department of Radiology
- Treatment of Osteosarcoma (cancer.gov)
- Wikipedia Listing for Osteosarcoma
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- Osteosarcoma (Emedicine)