|Table 3: Inhibitory effects of selected copper complexes.|
aValues refer to the most active copper (II) complex tested. Half- maximal inhibitory concentration (IC50) is a quantitative measure of the effectiveness of a compound in inhibiting a biological function as it indicates how much of a particular substance is needed to inhibit a given biological process. |
bValues in parenthesis refer to the free ligand.
cThese values refer to inhibitory dose (ID50): dose that inhibits 50% of Trypanosoma cruzi growth.
dThe exponentially growing cells were counted by haemocytometer using the Trypan blue exclusion method to quantify cell viability.