Affiliation: King's College London
- Global, voxel, and cluster tests, by theory and permutation, for a difference between two groups of structural MR images of the brainE T Bullmore
Department of Biostatistics and Computing, Institute of Psychiatry, King s College, University of London, UK
IEEE Trans Med Imaging 18:32-42. 1999..These issues are illustrated by application to MRI data acquired from 18 adolescents with hyperkinetic disorder and 16 control subjects matched for age and gender...
- Functional MR imaging of confounded hypofrontalityE Bullmore
Institute of Psychiatry, King s College, DeCrespigny Park, London, UK
Hum Brain Mapp 8:86-91. 1999....
- Functional anatomy of auditory verbal imagery in schizophrenic patients with auditory hallucinationsS S Shergill
Department of Biostatistics, Institute for Psychiatry, London, UK
Am J Psychiatry 157:1691-3. 2000..This study investigated the functional neuroanatomy of inner speech and auditory verbal imagery in schizophrenic patients predisposed to auditory hallucinations...
- Structural abnormalities in frontal, temporal, and limbic regions and interconnecting white matter tracts in schizophrenic patients with prominent negative symptomsT Sigmundsson
Institute of Psychiatry, Kings College, London
Am J Psychiatry 158:234-43. 2001....
- Reduced levels of GABA-benzodiazepine receptor in alcohol dependency in the absence of grey matter atrophyA R Lingford-Hughes
Department of Psychological Medicine, Institute of Psychiatry, London
Br J Psychiatry 173:116-22. 1998..We tested the hypothesis that reduced levels of the GABA-benzodiazepine receptor occur in alcohol dependency using single photon emission tomography (SPET) and the specific GABA-benzodiazepine ligand, 123I-iomazenil...
- Inhibition of subliminally primed responses is mediated by the caudate and thalamus: evidence from functional MRI and Huntington's diseaseA R Aron
Brain Mapping Unit, Department of Psychiatry, University of Cambridge, UK
Brain 126:713-23. 2003....
- Effects of very low birthweight on brain structure in adulthoodMatthew Allin
Department of Psychiatry, Institute of Psychiatry, King s College, London, UK
Dev Med Child Neurol 46:46-53. 2004..We conclude that these diffuse abnormalities of grey and white matter are a consequence of the interaction of perinatal brain injury and ongoing neurodevelopmental processes...
- Plasma level-dependent effects of methylphenidate on task-related functional magnetic resonance imaging signal changesUlrich Muller
MRC Behavioural and Clinical Neuroscience Centre, University of Cambridge, Cambridge, UK
Psychopharmacology (Berl) 180:624-33. 2005..Understanding of its cognition-enhancing effects and the neurobiological mechanisms involved, especially in elderly people, is currently incomplete...
- Brain mechanisms of successful compensation during learning in Alzheimer diseaseR L Gould
MRC Centre for Neurodegeneration Research, King s College London, Institute of Psychiatry, Section of Old Age Psychiatry, London, UK
Neurology 67:1011-7. 2006....
- Substantia nigra/ventral tegmental reward prediction error disruption in psychosisG K Murray
Brain Mapping Unit, Department of Psychiatry, Addenbrooke s Hospital, University of Cambridge, Cambridge, UK
Mol Psychiatry 13:239, 267-76. 2008..This study provides the first evidence linking abnormal mesolimbic activity, reward learning and psychosis...
- Multidimensional scaling of integrated neurocognitive function and schizophrenia as a disconnexion disorderD E Welchew
Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
Neuroimage 17:1227-39. 2002..However, there was significantly greater variability of interregional configurations within the group of patients with schizophrenia. The implications for schizophrenia as a disconnexion disorder are discussed...
- Effects of verbal working memory load on corticocortical connectivity modeled by path analysis of functional magnetic resonance imaging dataG D Honey
Department of Psychiatry, University of Cambridge, Cambridge CB2 2QQ, United Kingdom
Neuroimage 17:573-82. 2002..Enhanced inferior frontoparietal and prefrontoprefrontal connectivity was observed as a correlate of increasing memory load, which may reflect greater demand for maintenance and executive processes, respectively...
- A functional study of auditory verbal imageryS S Shergill
Institute of Psychiatry and GKT School of Medicine and Dentistry, University of London
Psychol Med 31:241-53. 2001..CONCLUSIONS: These results are consistent with the use of the 'articulatory loop' during both inner speech and auditory verbal imagery, and the greater engagement of verbal self-monitoring during auditory verbal imagery...
- Identifying rate-limiting nodes in large-scale cortical networks for visuospatial processing: an illustration using fMRIV W Ng
King's College London
J Cogn Neurosci 13:537-45. 2001..These data suggest that one region in a neurocognitive network may be most strongly associated with behavioral performance and this may be regarded as the computationally least efficient or rate-limiting node of the network...
- Neuroimaging correlates of negative primingC Steel
Department of Psychology, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
Neuroreport 12:3619-24. 2001..Areas of cortical activation are discussed with reference to theoretical accounts of the negative priming effect...
- A comparative evaluation of wavelet-based methods for hypothesis testing of brain activation mapsM J Fadili
Image Processing Group, GREYC CNRS UMR 6072 ENSICAEN 6, Bd du Maréchal Juin 14050, Caen Cedex, France
Neuroimage 23:1112-28. 2004....
- Acute ketamine administration alters the brain responses to executive demands in a verbal working memory task: an FMRI studyR A E Honey
Department of Psychiatry, University of Cambridge, Cambridge, UK
Neuropsychopharmacology 29:1203-14. 2004..Furthermore, we have shown that ketamine's effects may be elucidated by fMRI even when overt behavioral measures show no evidence of impairment...
- Dopaminergic effects on electrophysiological and functional MRI measures of human cortical stimulus-response power lawsO J Arthurs
Wolfson Brain Imaging Centre, Addenbrooke s Hospital, University of Cambridge, Cambridge, CB2 2QQ, UK
Neuroimage 21:540-6. 2004..Results indicate that sulpiride has comparable effects on power law parameters estimated from SEP and fMRI, but fMRI has superior sensitivity to detect drug effects on somatosensory cortical recruitment by graded stimulation...
- Lateralisation of language function in young adults born very pretermT M Rushe
Department of Psychology, University of Ulster at Jordanstown, N Ireland BT37 0QB, UK
Arch Dis Child Fetal Neonatal Ed 89:F112-8. 2004..To explore, using functional magnetic resonance imaging (MRI), the functional organisation of phonological processing in young adults born very preterm...
- Wavelet-generalized least squares: a new BLU estimator of linear regression models with 1/f errorsM J Fadili
Centre for Speech and Language, University of Cambridge, United Kingdom
Neuroimage 15:217-32. 2002..We conclude that wavelet-generalized least squares may be a generally useful estimator of regression models in data complicated by long-memory or fractal noise...
- GABAergic inhibitory mechanisms for repetition-adaptivity in large-scale brain systemsC M E Stephenson
Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2QQ, UK
Neuroimage 19:1578-88. 2003....
- Effect of slice orientation on reproducibility of fMRI motor activation at 3 TeslaS Gustard
Herchel Smith Laboratory for Medicinal Chemistry, School of Clinical Medicine, University of Cambridge, Cambridge, UK
Magn Reson Imaging 19:1323-31. 2001..Subtle inter-orientation differences are highlighted in the ROC analyses, which are not obvious by ANOVA; the oblique axial slice orientation offers the highest signal detection accuracy, whereas coronal slices give the lowest...
- Genetic contributions to regional variability in human brain structure: methods and preliminary resultsI C Wright
Institute of Psychiatry, King s College London, London, United Kingdom
Neuroimage 17:256-71. 2002..However, these preliminary re. sults suggest that genetic effects on structure of the human brain are regionally variable and predominantly symmetric in paralimbic structures and lateral temporal cortex...
- Functional magnetic resonance imaging of synesthesia: activation of V4/V8 by spoken wordsJ A Nunn
Department of Psychology, Goldsmiths College, London SE14 6NW, UK
Nat Neurosci 5:371-5. 2002..Control subjects showed no activity in V4/V8 when imagining colors in response to spoken words, despite overtraining on word-color associations similar to those spontaneously reported by synesthetes...
- Disrupted prediction-error signal in psychosis: evidence for an associative account of delusionsP R Corlett
Brain Mapping Unit, Department of Psychiatry, University of Cambridge, School of Clinical Medicine, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
Brain 130:2387-400. 2007..Our results support a neurobiological theory of delusion formation that implicates aberrant prediction-error signalling, disrupted attentional allocation and associative learning in the formation of delusional beliefs...