Open Peer Commentary Quartz & Sejnowski: Cognitive development
LTP is neither a memory trace nor an ultimate mechanism for its formation: The beginning of the end of the synaptic theory of neural memory
Lev P. Latash a1 a1 Department of Psychology, Institute for the Study of Developmental Disabilities, University of Illinois at Chicago, Chicago, IL 60613
The problem of neural memory storage is discussed, based on
the results of studies of memory impairment after hippocampal lesions,
motor learning, and electrophysiological research on “spinal
memory.” I support Shors & Matzel's major statements.
The absence of reliable evidence on the LTP memory storage function
and other data cast doubt on the synaptic theory of memory.