Tag: "toxins" at biology news
Protein protecting brain from toxins also blocks some chemotherapy from reaching tumors
.... "The ability of Mrp4 to protect the brain from toxins
can be a liability in people with brain cancer when this protein also blocks therapeutic drugs from reaching CNS tumors," said John Scheutz, Ph.D., an associate member of the St. Jude Department of Pharmaceutical Sciences. Schuetz is senior author of...
Reductions in blood oxygen levels in newborns could contribute to ADHD development
...s been attributed to genetic causes, environmental toxins
or maternal use of nicotine, alcohol or drugs. Also, researchers generally have believed that the newborn brain is somewhat resistant to subtle disturbances in blood oxygenation. This study demonstrates in rats, however, that while long-term decrea...
New center to map DNA of key lab mice
...g, we were able to expose a mouse to environmental toxins
and see 'if' a disease developed, but with genetic information, we can also understand 'why' a disease develops," said Olden. "Technology is accelerating both toxicology and environmental health research. NIEHS will lead the way in these two discipli...
Farmers don't need a new superstar toxin to fight bugs
WEST LAFAYETTE, Ind. - A new Michael Jordan of toxins
isn't required to increase crop protection against...ays thought that it would take a Michael Jordan of toxins
- a superstar of toxins
to effectively halt insect resistance to the current generation of insectici...
Common household fragrances may be harming aquatic wildlife, study finds
...ing with the animals' natural ability to eliminate toxins
from their system, according to a new Stanford Uni...that's embedded in the cell membrane and pumps out toxins
that get into the cell." For the experiment, gills were carefully sliced from living mussels and pla...
Scientists pioneer biotech techniques to halt infestation of history, art treasures in tropics
...a. It is now researching the promise of bacterial toxins
(BTtoxin, normally used to create insect-resistant crops) as a biological way to destroy and repel the pests, avoiding the traditional application of invasive technologies that often damage an artwork's colour and structure. Determining the species o...
Automated scans let scientists track drugs' broad effects on cells
...h well with one of 100 drugs -- both medicines and toxins
-- at different concentrations, and finished off the plates with11 chemical probes for different proteins and DNA. After 20 hours of cell growth, the researchers used automated microscopy to collect some half a million images of the treated cell...
NIEHS to develop new RNAi library to help fight disease
...e comprehensive understanding of how chemicals and toxins
can undermine our health. "This new technology gives us a stronger tool box for understanding the environmental response genes," said Dr. Kenneth Olden, NIEHS Director. "By focusing on the environmental response genes, we're building a library of RN...
HIV, diagnostic health care tools top of list for UH researchers
...earch projects involves biosensors that can detect toxins
and bacteria in an environment, ultimately leading to uses in diagnostic health care and biological/chemical detection. Presenting some of his latest breakthroughs in the fight against HIV, Krause will present research on the design of proteins ...
JCI table of contents, November 15 2004
...SSSS, Dsg1 is targeted for cleavage by exfoliative toxins
(ETs) of Staphylococcus aureus, however Amagai et al. found that ETs did not cleave Dsg4, suggesting that Dsg4 could not compensate for the loss of Dsg1 after ET cleavage. In sum, the authors concluded that Dsg4 must play a role other that adhesion i...
Genetic discovery paves way to decode sense of smell in mammals
...l for animals to detect food sources and potential toxins
and to identify suitable mates. The sensory ability depends initially on olfactory nerve cells in the lining of the nose. Scientists first identified olfactory receptors in mammals 10 years ago a discovery that won the 2004 Nobel Prize in Phys...
Vaccination with anthrax capsule protects against experimental infection in animals
..., thus allowing anthrax infection to progress. The toxins
are thought to act mainly by damaging defensive ce...use a response against PA is thought to target the toxins
only, there is interest in identifying additional potential anthrax vaccine components that target t...
New weapon in germ warfare: 'Jamming' bacteria signals stops cholera
...om escaping the host immune response and secreting toxins
to weaken their host," says Dr McDougald. Many bacteria rely on a signalling system known as quorum sensing to detect when enough of their own kind is present and then change their behaviour and attach themselves to a surface on a host or in...
Researchers discover direct link between agricultural runoff and massive algal blooms in the sea
...blooms, known as red or brown tides, which release toxins
in the water that can poison mollusks and fish. Excessively large blooms can also overwhelm a marine ecosystem by creating oxygen-depleted "dead zones" in the ocean. Scientists have long suspected that many harmful blooms are fueled by fertilizer run...
Researchers show how botulism toxin ensnares its target
...cognize the receptor. The new studies show how the toxins
that cause botulism and tetanus can recognize and ... development of drugs to block botulism or tetanus toxins
more rapidly in cases that have progressed beyond the stage at which antibiotics are effective.Howar...
Discovery about Vitamin C explains its metabolic value
...itamin C in the body continues to react with these toxins
to form conjugates - different types of molecules ...tective role against these oxidized lipids and the toxins
derived from them. And this isn't just test tube chemistry, this is the way our bodies work. "This d...
Yo-yo diet redistributes toxins in body tissue; Olestra+caloric cut boosts toxic excretion
...tion and perhaps more importantly, on excretion of toxins
from the body. Indeed, "combined dietary olestra ...showed with weight loss (with and without olestra) toxins
redistribute around the body, but with differing affinity to various organs. Method and results: b...
Inexpensive, mass-produced genes at core of synthetic biology advances at UH
...ning organisms that can produce energy, neutralize toxins
and make drugs and artificial genes that could eventually be used in gene therapy procedures. Gene therapy is a promising approach to the treatment of genetic disorders, debilitating neurological diseases such as Parkinson's and endocrine disorders ...
New painkiller was born in Utah
...y of Utah in 1979 by an incoming freshman studying toxins
produced by cone snails. The student, J. Michael McIntosh, worked in the laboratory of University of Utah biologist Baldomero "Toto" Olivera, the summer before his freshman year as the result of a scholarship interview. Now, 25 years later, Olive...
Development of portable infectious disease detector
...s of cells and studying how they respond to drugs, toxins
and pollutants. To do so, the interdisciplinary team has developed two basic technologies: special electrodes that can measure the concentrations of the chemicals that cells consume and excrete in extremely small volumes and the use of fluids flowing...
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