500 Boylston Street, Boston, MA 02116 617-419-4700
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A prospective, multi-center, unblended, two-arm, randomized trial. Designed to test the hypothesis that medical therapy with stenting of significant renal artery stenosis in patients with systolic hypertension reduces the incidence of adverse cardiovascular and renal events compared with medical therapy alone. The study will enroll patients with a history of systolic hypertension, who have documented renal artery stenosis. Patients will be randomized via several pathways to either medical therapy or medical therapy and with renal artery stenting and be closely monitored for blood pressure control and management of other risk factors.
Patients 18 and older with a documented history of hypertension and/or chronic kidney disease with a GFR <60 cc/min who are suspected to have renal artery stenosis. Patients on 2 or more anti-hypertensive medications. Severe renal artery stenosis of 60%-99% by angiogram, duplex systolic velocity of 300cm/sec or MRA documenting >80% stenosis.
Trial ID: Renal Artery Stenosis
Not Accepting Healthy Volunteers