Our laboratory is studying the three-dimensional structure of macromolecular
machines, organelles and cells using cryo-electron tomography.
We are focusing on the structure and function relationships of macromolecular
complexes in situ, i.e. in their native environment.
Areas of interest include the structure of eukaryotic flagella and the molecular
motor dynein, the cytoskeleton and bacteria, as well as the development of
Dymek et al. (2011) MBoC
cryo-EM and image processing techniques.