Our group studies the biology of mucosal epithelia during health and disease. We are particularly interested in understanding mechanisms that regulate intestinal epithelial homeostasis and barrier function under normal and inflammatory conditions.
Using complementary in vivo and in vitro experimental systems, our current projects are focused on understanding the basic mechanisms regulating:
Epithelial intercellular junctions and barrier function
Intestinal epithelial homeostasis
Mucosal wound repair
Immune cell recruitment and interactions with epithelial cells in health and disease