Two tables provide access to information about drug and drug target information from DrugBank that are mapped to PDB entries with each weekly update. These tables, accessed from the Tools menu, can be searched, filtered, and sorted.
- Drugs Bound to Primary Targets: Lists drugs bound to primary target(s), or a homolog of primary target(s), i.e., co-crystal structures of drugs.
- Primary Drug Targets: Lists primary drug targets in the PDB, regardless if the drug molecule is part of the PDB entry (e.g., apo forms of drug targets, drug target with different bound ligands). Biotherapeutics, such as complexes with monoclonal antibodies, are included.
The top 3 PDB IDs for each drug based on the drug target sequence similarity search and ligand id search. If the sequence identities are same, the PDB ID with better resolution will take precedence.