Prof.Dr.Stehling Institut für Bildgebende DIAGNOSTIK
Strahlenberger Straße 110
63067 Offenbach - Kaiserlei
Phone: +49 69-50 50 00 90
Fax: +49 69-50 50 00 98-8
Monday-Friday: 8:00 am – 8:00 pm
Saturday: 10:00 am – 2:00 pm
Sunday and Bank Holidays:
Researchers focused on CCSVI now assume that there might be a links between Parkinson’s disease and CCSVI.
Iron deposits in the basal ganglia in Parkinson’s patients accumulate upstream from the venous drainage route. In some of these patients, venous stenoses, as described in CCSVI, have been identified. The similar iron deposition was found also in patients with Alzheimer’s (also known as Dementia) disease.
Also ALS (also Motor Neuron Disease (MND) or Lou Gehrig's disease) research shows that this disease is started by blood-spinal cord-barrier (BSCB) damage. Blood flow effects explain the blood-brain-barrier (BBB) damage in MS and may explain the BSCB damage in ALS. One of the hypotheses is that ALS is caused by constrictions in the vein draining the spinal cord and brain, which cause the venous reflux, which downregulates tight junction proteins Occludin and ZO-1, which leads to breaks in the tight junctions between endothelial cells in the veins, which leads to leakage of toxic blood components into CNS tissue. If a venous constriction can be reached endovascularly it can be dilated, and such dilation may constitute cure of ALS.
To further explore these findings, the CCSVI-Center in Frankfurt, Germany, has begun to examine patients with other degenerative diseases like Parkinson, ALS and Alzheimer with a special Haacke MRI-protocol and duplex sonography to determine, whether the CCSVI criteria can be found in a higher percentage of cases than in the normal population.
+49 69-50 50 00 90
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