timing: Lent term, 16 lectures
assessment: written exam (1.5 hours) at the start of Easter term
module leader: Alexandre Kabla (ajk61)
This course focuses on the quantitative modelling of biological systems. A wide variety of topics are touched upon, from biochemistry and cellular function to neural activity and respiration. In all cases, the emphasis is on finding the simplest mathematical model that describes the observations and allows us to identify the relevant physiological parameters. The models often take the form of a simple functional relationship between two variables, or a set of coupled differential equations. The course tries to show where the equations come from and lead to: what assumptions are needed and what simple and robust conclusions can be drawn.
Dr. Alexandre Kabla
|Physical and chemical principles||Handouts||examples paper 0 (IB revisions) |
examples paper 1
Dr. Máté Lengyel
channel currents: slides notes
resting membrane potential: slides
action potential: slides
|Dr. Alexandre Kabla||Physiological systems||Handouts 2
examples paper 2
|Dr. Alexandre Kabla||Coursework: |
Matlab file default_params.m
Matlab file run_oscil.m
Matlab ode45 Help file
Laje et al. (2001)
Please use the link below (click on the dates) to sign up to exactly one of the supervision time slots. Each time slot can fit up to 4 students on a first-come, first-served basis. Make sure you use your CRSid for signing up. Note: if you so wish, it is possible to prevent others editing your choice of supervision slot by signing into a (free) Doodle account before entering your CRSid & time choice.
Physical and chemical principles (4L, A. Kabla)
Electrophysiology (5L, M. Lengyel)
Blood Physiology (3L, A. Kabla)
Physiological transport systems (4L, A. Kabla)
Physiology of speech production. Vocal tract acoustics & dynamics of the vocal folds.
(Only selected chapters of these books are covered during the course.)
Main text book
Keener J, Sneyd J. Mathematical Physiology. Springer, 2004.
Berg et al. Biochemistry (6th edition). W. H. Freeman and Co., 2007.
Kandel ER, Scwartz JH, Jessel TM. Principles of Neural Science (4th edition). McGraw-Hill, 2000.
see also Booklist for IIA courses