Affiliation: Vanderbilt University
- Optical stimulation of neural tissue in vivoJonathon Wells
Departments of Biomedical Engineering and Neurosurgery, Vanderbilt University, 2201 West End Avenue, Nashville, Tennessee 37235, USA
Opt Lett 30:504-6. 2005..Thus optical stimulation presents a simple yet novel approach to contact-free in vivo neural activation that has major implications for clinical neurosurgery, basic neurophysiology, and neuroscience...
- Pulsed laser versus electrical energy for peripheral nerve stimulationJonathon Wells
Vanderbilt University, Department of Biomedical Engineering, 5824 Stevenson Center, Nashville, TN 37235, United States
J Neurosci Methods 163:326-37. 2007..Thus, use of a pulsed laser exhibits distinct advantages when compared to standard electrical means for excitation of muscle potentials in the peripheral nerve in the research domain and possibly for clinical diagnostics in the future...
- Biophysical mechanisms of transient optical stimulation of peripheral nerveJonathon Wells
Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235, USA
Biophys J 93:2567-80. 2007..8 degrees C-6.4 degrees C), resulting in direct or indirect activation of transmembrane ion channels causing action potential generation...
- Application of infrared light for in vivo neural stimulationJonathon Wells
Vanderbilt University, Department of Biomedical Engineering, Box 351631, Station B, Nashville, Tennessee 37235, USA
J Biomed Opt 10:064003. 2005..g., noncontact, spatial resolution, lack of stimulation artifact) over conventional electrical methods in diagnostic and therapeutic procedures in neuroscience, neurology, and neurosurgery...
- Laser stimulation of auditory neurons: effect of shorter pulse duration and penetration depthAgnella D Izzo
Department of Otolaryngology, Northwestern University, Chicago, Illinois 60611, USA
Biophys J 94:3159-66. 2008..The implications of these data could direct further research and design of an optical cochlear implant...