The theory of natural selection (part 2)
This tutorial is mainly concerned with how natural selection can maintain genetic polymorphism. We look at selection-mutation balance, heterozygous advantage, and frequency-dependent selection; and we finish by looking at models that include migration in a geographically subdivided population. The theory in this tutorial all assumes that the population size is large; the next tutorial discusses how random effects operate in small populations.
- How can we measure fitness?
- How does natural selection deal with recurrent unfavorable mutations?
- Why does sickle cell anemia persist at high frequencies?
- Is fitness dependent on frequency?
- What are the sources of polymorphism?
- What are the effects of population subdivisions?
- What are the effects of migration?