Andrews is located at 40°51′39″N 85°36′3″W (40.860824, -85.600960).
According to the 2010 census, the town has a total area of 0.65 square miles (1.7 km), of which 0.64 square miles (1.7 km) (or 98.46%) is land and 0.01 square miles (0.026 km) (or 1.54%) is water.
As of the census of 2000, there were 1,290 people, 470 households, and 351 families residing in the town. The population density was 2,602.2 people per square mile (996.1/km). There were 534 housing units at an average density of 1,077.2 per square mile (412.4/km). The racial makeup of the town was 97.05% White, 0.08% African American, 1.09% Native American, 0.16% Asian, 0.08% from other races, and 1.55% from two or more races. Hispanic or Latino of any race were 2.17% of the population.
There were 470 households out of which 37.7% had children under the age of 18 living with them, 57.7% were married couples living together, 11.3% had a female householder with no husband present, and 25.3% were non-families. 20.0% of all households were made up of individuals and 7.4% had someone living alone who was 65 years of age or older. The average household size was 2.74 and the average family size was 3.16.
In the town the population was spread out with 31.0% under the age of 18, 7.0% from 18 to 24, 31.5% from 25 to 44, 19.1% from 45 to 64, and 11.5% who were 65 years of age or older. The median age was 33 years. For every 100 females there were 102.8 males. For every 100 females age 18 and over, there were 98.7 males.
The median income for a household in the town was $35,125, and the median income for a family was $36,150. Males had a median income of $30,580 versus $19,891 for females. The per capita income for the town was $15,198. About 6.2% of families and 8.2% of the population were below the poverty line, including 9.0% of those under age 18 and 9.4% of those age 65 or over.