Intake of dietary fiber, especially from cereal foods, is associated with lower incidence of colon cancer in the HELGA cohort
International Journal of Cancer, 04/20/2012
Hansen L et al. – The data indicate a protective role of total and cereal fiber intake, particularly from cereal foods with high fiber content, in the prevention of colon cancer.
The authors included 1,168 incident cases (691 colon, 477 rectal cancer), diagnosed during a median of 11.3years, among 108,081 cohort members.
Sex-specific incidence rate ratios (IRRs) of colon and rectal cancer were related to intake of total or specific fiber source using Cox proportional hazards models.
For men, an inverse association was observed between intake of total fiber and the risk of colon cancer per an incremental increase of 10g day-1, IRR (95% CI): 0.74 (0.64-0.86).
Intake of cereal fiber per 2gday-1 was associated with an IRR of 0.94 (0.91-0.98), which was also seen for intake of cereal fiber from foods with high fiber content (≥5g per 100g product), where the IRR per 2gday-1 was 0.94 (0.90-0.98).
In women, intake of cereal fiber per 2gday-1 was also associated with lower risk of colon cancer, 0.97 (0.93-1.00).
No clear associations were seen for rectal cancer.
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