Tirin Moore, Ph.D.
Visual perception, attention, cognition, eye movements, sensorimotor integration, systems neuroscience, cerebral cortex, motor control, pattern recognition
We study neural mechanisms of visual-motor integration and the neural basis of cognition (e.g. attention). We study the activity of single neurons in visual and motor structures within the primate brain, examine how perturbing that activity affects neurons in other brain structures, and also how it affects the perceptual and motor performance of behaving animals. Questions currently addressed by our group include: (1) How are the signals conveyed by visual cortical neurons used to guide eye movements? (2) How does oculomotor feedback affect processing in visual cortex? (3) What is the impact of planned movements on visual perception? (4) What are the neural circuits and neural computations that control selective attention? Our laboratory is also driven to develop more powerful approaches to systems-level neurobiological questions.
Moore, T. and Armstrong, K.M. (2003) Selective Gating of Visual Signals by Microstimulation of Frontal Cortex, Nature, 421: 370-373.
Graziano, M.S.A., Taylor, C.S.R. and Moore, T. (2002) Complex Movements Evoked by Stimulation of Precentral Cortex, Neuron, 34: 841-851.
Moore, T. and Fallah, M. (2001) Control of Eye Movements and Spatial Attention. Proc. Nat’l Acad. Sci. USA., 98: 1273-1276.
Tolias, A.S., Moore, T., Smirnakis, S.M., Tehovnik, E.J., Siapas, A.G., and Schiller, P.H. (2001) Eye Movements Modulate Visual Receptive Fields of V4 Neurons. Neuron, 29: 757-767.
Moore, T. (1999) Shape Representations and Visual Guidance of Saccadic Eye Movements. Science, 285: 1914-1917.
Moore, T., Armstrong, K.M., and Fallah, M. Visuomotor Origins of Covert Spatial Attention.
Neuron, (in press).
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Last updated: 01/16/04