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In biochemistry, indoleamines are substituted indole compounds that contain an indole ring with five members and an amino group (NH2). Examples of indoleamines are serotonin, tryptamines and the lysergamides. Another example of an indolamine is melatonin, which regulates the sleep-wake cycle (circadian rhythm) in humans.
In humans, neurotransmitters in the indolamine family are believed to be produced in the pineal gland. Indolamines are biologically synthesized from the essential amino acid tryptophan.
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