Drosophila: A Toolbox for the Study of Neurodegenerative Disease
Edited by Amritpal Mudher, Tracey Newman
Taylor & Francis – 2007
Series: Society for Experimental Biology
Drosophila gives an overview of the ways in which Drosophila is currently being used as a model organism to further our understanding of a spectrum of human neurological diseases. Each chapter is written by respected researchers and gives an excellent account of the subject that is suitable for postgraduate and postdoctoral researchers.
1. Modelling Neurodegenerative Diseases in Drosophila 2. Drosophila Genetics for the Analysis of Neurobiological Disease 3. Using Drosophila Models to Unravel Pathogenic Mechanisms That Underlie Neurodegeneration in Tauopathies 4. Modelling Cell and Isoform Type Specificity of Tauopathies in Drosophila 5. Using a Drosophila Model of Alzheimer's Disease 6. Amyloid Peptides and Ion Channel Function in Drosophila Models of Alzheimer's Disease 7. Genetic Models of Parkinson's Disease: Mechanisms and Therapies 8. Modeling Lyosomal Storage Disease in Drosophila 9. Drosophila melanogaster in the Study of Epilepsy 10. Hereditary Spastic Paraplegia Genes in Drosophila: Dissecting Their Roles in Axonal Degeneration and Intracellular Traffic 11. Triplet Repeat Diseases - Role of Fly Models in Understanding Disease Mechanisms and Designing Possible Therapies