Extracardiac Complications After Cardiac Surgery
Hypothesis of the study is that patients undergoing major cardiac surgery can develop extracardiac complications correlated to cardiopulmonary by pass.
Acute Lung Injury
Acute Kidney Injury
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Extracardiac Complications After Cardiopulmonary by Pass in Cardiac Surgery|
- Acute Lung Injury After Cardiac Surgery [ Time Frame: at seven days after intervention ] [ Designated as safety issue: No ]to evaluate the incidence of acute lung injury (ALI) in patients undergoing cardiac surgery with cardiopulmonary by pass and to identify the main predictors.Diagnosis of Acute Lung Injury (ALI) was made according to the American-European Consensus conference criteria, including acute onset, PaO2 /FiO2 <300 regardless of Positive End Expiratory Pressure (PEEP) level, bilateral and diffuse opacities on chest radiograph, absence of left ventricular failure, or history of lung disease.
- Intensive Care Unit (ICU) Length of Stay [ Time Frame: at 28 days ] [ Designated as safety issue: No ]If extracardiac complications, especially acute lung injury, prolonged Intensive Care Unit (ICU) length of stay due to longer mechanical ventilation.
|Study Start Date:||April 2007|
|Study Completion Date:||December 2009|
|Primary Completion Date:||December 2008 (Final data collection date for primary outcome measure)|
Acute Lung Injury (ALI)
patients who might develop acute lung injury (ALI) after cardiac surgery with cardiopulmonary by pass
To find out which are the main peri operative predictors of acute lung injury and other extracardiac complications, such as kidney injury, that prolonged Intensive Care Unit (ICU) length of stay after cardiac surgery. The main goal is to evaluate whether mechanical ventilation, in particular tidal volume, can be predictor of acute lung injure in this kind of patients.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01187004
|Cardiac Intensive Care Unit, San Giovanni Battista Hospital|
|Turin, Italy, 10126|
|Study Chair:||Mauro Rinaldi, MD||San Giovanni Battista Hospital, University of Turin|