Definition of Mechanism of action
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Mechanism of action Definition from Medicine Dictionaries & Glossaries
The specific manner by which a substance causes a particular effect.No copyright message
Mechanism of action Definition from Encyclopedia Dictionaries & Glossaries
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In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor. Receptor sites have specific affinities for drugs based on the chemical structure of the drug, as well as the specific action that occurs there. Drugs that do not bind to receptors produce their corresponding therapeutic effect by simply interacting with chemical or physical properties in the body. Common examples of drugs that utilize this method are antacids and laxatives.
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