The Bartoli Brain Tumor Laboratory is part of Columbia University Medical Center and headed by Dr. Jeffrey Bruce and Dr. Peter Canoll. We are a multidisciplinary group of researchers and clinicians dedicated to the care of patients with brain tumors, primarily glioblastoma multiforme (GBM), the most common and aggressive malignant primary brain tumor. Members of our lab include neurosurgery residents, postdoctoral and senior researchers, medical students, lab technicians, and interns from the Department of Neurological Surgery and the Department of Pathology and Cell Biology.
Using both human tissue and animal models, we combine our scientific study of the mechanisms of tumorigenesis, the diversity of tumor cell populations, and immune responses to brain tumors, with the development of therapies for brain tumor patients. Our lab has pioneered the creation of de novo tumors that most closely recapitulate the development of GBM natively in rodent models. In collaboration with the Herbert Irving Comprehensive Cancer Center (HICCC) at Columbia University Medical Center, the Bartoli Brain Tumor Laboratory curates a valuable repository or tumor specimens from patients for short- and long-term studies, with the promise of unique advances in characterizing human brain tumors and bolstering collaborative efforts with other hospitals and labs.