β-Cell Function Across the Spectrum of Glucose Tolerance in Obese Youth
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The proinsulin-to-insulin ratio during acute-phase insulin secretion. Proinsulin-to-insulin ratio during the hyperglycemic
clamp. P < 0.001 and P = 0.01 for 4 min, P = 0.001 and P = 0.04 for 6 min for type 2 diabetes (red) vs. NGT (blue) and IGT (yellow).