Used with the ProteOn™ XPR36 protein interaction array system, ProteOn sensor chips are prepared with a modified alginate polymer layer bound to the gold surface of the sensor prism. This layer provides the net negative charge and active ligand binding sites. The result is user-controlled sensitivity down to the subnanogram level.
The ProteOn NLC sensor chip is designed for general amine coupling and has NeutrAvidin bound to the GLC polymer layer with a binding capacity of approximately one protein monolayer. It is suitable for immobilization of biotinylated proteins, peptides, and nucleic acids.
Each ProteOn sensor chip is enclosed in a bar-coded cartridge for data tracking and archiving. Chips have long-term storage stability and all six ligand channels may be used across different experiments.
The ProteOn XPR36 system includes all of the components required for interaction analysis: instrumentation, ProteOn Manager™ software, sensor chips, buffer and reagent kits, and protocol development kits.