Tag: "identified" at biology news
The CF Foundation urges all states to include newborn screening for cystic fibrosis in test panels
...ed with CF. CF is one of the most common disorders identified
in the newborn screening programs that include it in their testing....
Study identifies target for preventing sexual transmission of HIV
... transmission in heterosexual intercourse and have identified
the target for blocking that transmission, accordi...ng transmission of HIV through the vagina. We have identified
a potential target, a mechanism critical for the transmission at vaginal sites of infection, that ma...
Identifying genes that contribute to a low level of response to alcohol
...a genetic link. A review of previous research has identified
several categories of genes of potential interest....ults, searching for potential patterns. Reviewers identified
several genes that may contribute to a low LR to alcohol, and thus, to an elevated risk for alcohol-...
Sniffing out the culprits of dust allergies
...ease-specific inhibitors. In this way, Der 1 p was identified
as an active cysteine protease in dust mite extracts, and a Der 1 p-specific small-molecule inhibitor was isolated from a peptide nucleic acid (PNA)-encoded small-molecule library. As a result of this investigation, Der 1 p was implicated in the clea...
Intracellular protein localization involved in new tumor progression pathway
...tablishment and progression of tumors. The authors identified
a specific mitochondrial pool of survivin that is released into the cytoplasm when a cell receives signals to undergo cell death. Once in the cytoplasm, survivin inhibits enzymes called caspases which are required for apoptosis, and in doing so, bloc...
Antibiotic identified as potential anti-cancer candidate
...erial-exclusive enzyme, genome-based data searches identified
several classes of Pdf-like sequences in parasites, plants and mammals. Subsequent studies showed that the Pdfs were active both in culture and in the living organism, thus potentially derailing the usefulness of these antibiotics for specifically c...
Excess dietary fat accelerates breast cancer by altering the activity of a group of genes
...ular, de Fisiologia i d'Immunologia of the UAB has identified
four genes, one which has a completely unknown function, whose expression may be involved in this effect caused by dietary lipids. More extensive research into these genes is required to discover whether the mechanism discovered works in the same way...
Zebrafish may offer researchers powerful new tool for studying innate immunity
...ues. They searched the genome of the zebrafish and identified
a class of genes, called novel immune-type receptor (NITR) genes, which are predicted to be capable of recognizing a wide range of surface molecules. A portion of the NITR genes is very similar to variable region genes of antibodies and T-cell recept...
Consuming fruits and vegetables lowers risk of developing NHL
...h NHL between the ages of 20 to 74 years, who were identified
from four large cancer registries across the country. These study participants were matched to approximately 400 individuals without cancer who were similar in age, sex, race and lived in the same geographical region. "This t...
Expert panel offers prelimary report on health effects of assisted reproductive technologies
...ly conceived multiple births. The panel also identified
a number of gaps in existing knowledge and is developing recommendations for well-designed research and surveillance efforts, recommendations for clinicians, including what information should be provided to patients, and recommendations for public po...
Gene for Joubert syndrom with excessive brain folds discovered by UCSD researchers and Harvard team
...by a team from Harvard Medical School concurrently identified
the same gene in a paper published in the November...though there will ultimately be several more genes identified
that can lead to the various forms of Joubert Syndrome, our discovery will help those individuals wi...
Early life stress can inhibit development of brain-cell communication zones, UCI study finds
...ychiatry. For the first time, the researchers have identified
how increased amounts of a key messenger for stress, the neuropeptide CRH, can inhibit the normal growth of dendrites, which are branch-like protrusions of neurons that send and receive messages from other brain cells. The researchers believe CRH ul...
International human genome sequencing consortium describes finished human genome sequence
...9,599 protein-coding genes in the human genome and identified
another 2,188 DNA segments that are predicted to b...eath of genes in the human genome. Scientists have identified
more than 1,000 new genes that arose in the human genome after our divergence with rodents some 75 m...
New DNA repair enzyme makes mistakes to save lives of cells
...sumption. When Dr. Wood and his colleagues first identified
POL-Q last year they reported that because of its protein structure it belonged to the A family of polymerases, which are known for filling gaps during DNA replication. Now with a better understanding of how its role is to permit replication to proce...
New genomic method can identify disease-causing genes
...rts that the new computational algorithm correctly identified
the genetic basis for strain-specific differences in several biologically important traits, including differences in drug metabolism. The examples presented in the paper demonstrate the ability of the methodology to identify causative genetic factors...
Study is looking at ways to help stroke survivors regain lost motor skills
...the protective membrane over the area of the brain identified
by the MRI as affected by stroke. The electrode connects to a pulse generator implanted below the collarbone. At the end of six weeks of intensive occupational therapy and completion of required follow-up periods, the device is removed. Doctors h...
Single genetic defect links many risk factors for heart disease and stroke
...lated decline in mitochondrial function, which was identified
by Shulman. Lifton has no illusions that defining...ms underlying such linkages will be easy. "We have identified
this defect and linked it with these traits, but there remains a complex black box in between," he s...
Newly discovered protein suggests novel tumorigenic pathway
...NA to find proteins that interact with PTEN. They identified
a new protein that binds to the C-terminus of PTEN and named it PICT-1 ( p rotein i nteracting with the c arboxyl t erminus 1). Maehama and his colleagues discovered that PTEN molecules with mutations in their C-terminus are unable to bind to PI...
Researchers discover gene mutations for Parkinson's disease
...e region of Spain and in England. First, the group identified
a small region of the chromosome 12 shared by all ...ations that might cause disease. The investigators identified
two mutations in the same gene, one associated with Parkinson's disease in the Basque families and t...
Gene for common form of Parkinson's pinpointed
Researchers have identified
a new gene that causes a common form of inherited ...hat contained about 116 genes. The researchers had identified
four families from the Basque region of Spain and one from the United Kingdom that showed evidence o...
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