Mark.Haynes at mail.tju.edu
Tue Feb 11 15:19:45 EST 1997
Rachel Teitelbaum wrote:
> There was a while back a treatment I thought was promising, but have lost
> sight of the follow-up. Anyone out there know what happened? They were
> transfecting cancer cells with a plasmid containing the gene for a
> costimulatory molecule, called B7.
I think I too remember someting of this sort. I'm sure its a model
though. Transfection would necessarily have to be done on a personal
basis. Also, because the co-receptors for the B7 family are implicated
in stimulation (CD28) or tolerance (CTLA$), it would be important to to
somehow skew the results toward interaction with CD28.
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