Material Safety Data Sheet
Section 1 - Chemical Product and Company Identification
MSDS Name: Sodium fluoride
AC191270000, AC191270010, AC191270250, AC191275000, AC201290000,
AC201290250, AC201295000, AC424320000, AC424320050, AC424325000, S299-100,
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
|| >97 ||231-667-8
Section 3 - Hazards Identification
Appearance: white to off-white crystalline powder.
Danger! Causes irritation and possible burns by
all routes of exposure. May be fatal if swallowed. Contact with
acids liberates toxic gas. May cause lung damage. Moisture
Target Organs: Kidneys, heart, gastrointestinal
system, skeletal structures, teeth, nerves, bone.
Potential Health Effects
Causes eye irritation and possible burns. May cause chemical
conjunctivitis and corneal damage.
Contact with skin causes irritation and possible burns, especially
if the skin is wet or moist. May cause skin rash (in milder cases),
and cold and clammy skin with cyanosis or pale color.
May be fatal if swallowed. Ingestion of large amounts of fluoride
may cause salivation, nausea, vomiting, abdominal pain, fever,
labored breathing. Exposure to fluoride compounds can result in
systemic toxic effects on the heart, liver, and kidneys. It may also
deplete calcium levels in the body leading to hypocalcemia and death.
May cause irritation of the digestive tract and possible burns. May
cause respiratory paralysis and cardiac arrest.
May cause severe irritation of the respiratory tract with possible
burns. Aspiration may lead to pulmonary edema. Prolonged exposure to
dusts, vapors, or mists may result in the perforation of the nasal
septum. May cause systemic effects.
Chronic inhalation and ingestion may cause chronic fluoride
poisoning (fluorosis) characterized by weight loss, weakness,
anemia, brittle bones, and stiff joints. Effects may be delayed.
Chronic exposure may cause lung damage. Laboratory experiments have
resulted in mutagenic effects. Chronic exposure to fluoride compounds
may cause systemic toxicity. Skeletal effects may include bone
brittleness, joint stiffness, teeth discoloration, tendon
calcification, and osterosclerosis. Animal studies have reported the
development of tumors.
Section 4 - First Aid Measures
Get medical aid immediately. Do NOT allow victim to rub eyes or keep
eyes closed. Extensive irrigation with water is required (at least 30
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask.
Notes to Physician:
Individuals who suffer from diabetes insipidus or some form of renal
impairment may be at increased risk from the effects of fluoride. Due
to delayed and persistent symptoms, observe patient closely for 48
hours. Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Material will not burn. During a fire, irritating
and highly toxic gases may be generated by thermal decomposition or
Use extinguishing media most appropriate for the surrounding fire.
Do NOT get water inside containers. Use water spray, dry chemical,
carbon dioxide, or appropriate foam.
Flash Point: Not available.
Autoignition Temperature: Not available.
Explosion Limits, Lower:Not available.
Upper: Not available.
(estimated) Health: 3; Flammability: 0; Instability: 0
Section 6 - Accidental Release Measures
General Information: Use proper personal protective equipment as indicated
in Section 8.
Vacuum or sweep up material and place into a suitable disposal
container. Do not flush into a sewer. Clean up spills immediately,
observing precautions in the Protective Equipment section. Avoid
generating dusty conditions. Provide ventilation. Do not get water
Section 7 - Handling and Storage
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Minimize dust
generation and accumulation. Do not get in eyes, on skin, or on
clothing. Keep container tightly closed. Do not ingest or inhale. Do
not allow contact with water. Discard contaminated shoes. Keep from
contact with moist air and steam.
Keep container closed when not in use. Store in a tightly closed
container. Store in a cool, dry, well-ventilated area away from
incompatible substances. Keep away from strong acids. Store protected
from moisture. Store away from alkalies.
Section 8 - Exposure Controls, Personal Protection
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
||OSHA - Final PELs|
2.5 mg/m3 TWA (as F) (listed under Fluorides).
2.5 mg/m3 TWA (as F) 250 mg/m3 IDLH (as F)
2.5 mg/m3 TWA (as dust) (listed under Fluorides).2.5 mg/m3 TWA (as F) (listed under Fluorides).
OSHA Vacated PELs:
No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Wear appropriate protective gloves to prevent skin
Wear appropriate protective clothing to prevent skin
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
Section 9 - Physical and Chemical Properties
Physical State: Crystalline powder
Appearance: white to off-white
pH: 7.4 (solution)
Vapor Pressure: 1 mm Hg @ 1077 deg C
Vapor Density: 1.45 (air=1)
Evaporation Rate:Not available.
Viscosity: Not available.
Boiling Point: 1704 deg C
Freezing/Melting Point:993 deg C
Decomposition Temperature:Not available.
Specific Gravity/Density:2.78 (water=1)
Section 10 - Stability and Reactivity
Stable under normal temperatures and pressures. Moisture sensitive.
Conditions to Avoid:
Incompatible materials, dust generation, moisture, excess heat.
Incompatibilities with Other Materials:
Moisture, acids, alkalies, glass, oxidizing agents.
Hazardous Decomposition Products:
Irritating and toxic fumes and gases, hydrogen fluoride gas, sodium
Hazardous Polymerization: Will not occur.
Section 11 - Toxicological Information
rabbit, eye: 20 mg/24H Moderate;
Oral, mouse: LD50 = 44 mg/kg;
Oral, rabbit: LD50 = 200 mg/kg;
Oral, rat: LD50 = 31 mg/kg;
Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Oral, rat: TDLo = 617 mg/kg/2Y-C (Tumorigenic - equivocal
tumorigenic agent by RTECS criteria - Endocrine - thyroid
tumorsand Musculoskeletal - tumors.; Oral, mouse: TDLo = 14
mg/kg/43W-C (Tumorigenic - equivocal tumorigenic agent by
RTECS criteria - Skin and Appendages - tumors.
Oral, rat: TDLo = 240 mg/kg (female 11-14 day(s) after
conception) Specific Developmental Abnormalities -
musculoskeletal system.; Oral, rat: TDLo = 255 mg/kg
(female 85 day(s) pre-mating) Specific Developmental
Abnormalities - Central Nervous System.; Intraperitoneal,
rat: TDLo = 9 mg/kg (female 10-18 day(s) after conception)
Effects on Embryo or Fetus - extra-embryonic structures
(e.g., placenta, umbilical cord) and Effects on Embryo or
Fetus - fetal death.
Oral, rat: TDLo = 150 mg/kg (male 30 day(s) pre-mating)
Reproductive - Paternal Effects - spermatogenesis (incl.
genetic material, sperm morphology, motility, and count)
and Paternal Effects - testes, epididymis, sperm duct and
Fertility - male fertility index (e.g. # males impregnating
females per # males exposed to fertile nonpregnant
females).; Oral, rat: TDLo = 221 mg/kg (female 1-20 day(s)
after conception) Fertility - post-implantation mortality
(e.g. dead and/or resorbed implants per total number of
DNA Inhibition: Human, Fibroblast = 100 mg/L.; Cytogenetic
Analysis: Human, Fibroblast = 20 mg/L.; Cytogenetic
Analysis: Human, Lymphocyte = 20 mg/L.; Mutation in
Mammalian Somatic Cells: Human, Lymphocyte = 440 mg/L.
No information found
Section 12 - Ecological Information
Fish: Mosquito Fish: TLm = 419 ppm; 96 Hr; Fresh waterWater flea
Daphnia: LC50 = 340 mg/L; 48 Hr; Unspecified
No data available.
Toxic to aquatic and plant life. Soil can bind fluorides tightly if
the pH is greater than 6.5. Fluorides can be damaging to plants when
present in acid soils.
No information available.
Dangerous to aquatic life in high concentrations.
Section 13 - Disposal Considerations
Chemical waste generators must determine whether a discarded chemical is classified
as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3.
Additionally, waste generators must consult state and local hazardous waste regulations to
ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 - Transport Information
||SODIUM FLUORIDE, SOLID
Section 15 - Regulatory Information
CAS# 7681-49-4 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
CAS# 7681-49-4: 1000 lb final RQ; 454 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
CAS # 7681-49-4: immediate, delayed.
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 7681-49-4 is listed as a Hazardous Substance under the CWA.
None of the chemicals in this
product are listed as Priority Pollutants under the CWA.
None of the chemicals in this
product are listed as Toxic Pollutants under the CWA.
None of the chemicals in this product
are considered highly hazardous by OSHA.
CAS# 7681-49-4 can be found on the
following state right to know lists: California, New Jersey,
Pennsylvania, Minnesota, (listed as Fluorides, inorganic),
Minnesota, (listed as Fluorides), Massachusetts.
California Prop 65
California No Significant Risk Level:
None of the chemicals in this product are listed.
European Labeling in Accordance with EC Directives
R 25 Toxic if swallowed.
R 32 Contact with acids liberates very toxic gas.
R 36/38 Irritating to eyes and skin.
S 22 Do not breathe dust.
S 36 Wear suitable protective clothing.
S 45 In case of accident or if you feel unwell, seek medical advice
immediately (show the label where possible).
WGK (Water Danger/Protection)
CAS# 7681-49-4: 1
Canada - DSL/NDSL
CAS# 7681-49-4 is listed on Canada's DSL List.
Canada - WHMIS
This product has been classified in accordance with the hazard
criteria of the Controlled Products Regulations and the MSDS
contains all of the information required by those regulations.
Canadian Ingredient Disclosure List
CAS# 7681-49-4 is listed on the Canadian Ingredient Disclosure List.
Section 16 - Additional Information
MSDS Creation Date: 7/07/1999
Revision #6 Date: 2/15/2008
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no event shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.