Affiliation: Yale University
- Neuron-specific feeding RNAi in C. elegans and its use in a screen for essential genes required for GABA neuron functionChristopher Firnhaber
Department of Genetics, Program in Cellular Neuroscience, Neurodegeneration, and Repair, Yale University School of Medicine, New Haven, Connecticut, United States of America
PLoS Genet 9:e1003921. 2013..We identified 48 genes whose GABA cell-specific knockdown resulted in reduced GABA motor output. This screen extends our understanding of the genetic requirements for continued neuronal function in a mature organism. ..
- Neural regeneration in Caenorhabditis elegansRachid El Bejjani
Department of Genetics, Program in Cellular Neuroscience, Neurodegeneration, and Repair, Yale University, New Haven, Connecticut 06510, USA
Annu Rev Genet 46:499-513. 2012..elegans have broadly similar roles in vertebrate neurons. This means that using C. elegans as a tool to leverage discovery is a legitimate strategy for identifying conserved mechanisms of axon regeneration...
- Horseman, pass by: finding post-developmental functions of essential genesMarc Hammarlund; Fiscal Year: 2010....