Grindstone-Rowes Run is a census-designated place (CDP) in Fayette County, Pennsylvania, United States. The population was 1,141 at the 2000 census. The village is Grindstone is located in Jefferson Township, while Rowes Run is located in Redstone Township.
There were 484 households out of which 24.6% had children under the age of 18 living with them, 47.3% were married couples living together, 14.0% had a female householder with no husband present, and 33.1% were non-families. 30.0% of all households were made up of individuals and 18.4% had someone living alone who was 65 years of age or older. The average household size was 2.36 and the average family size was 2.92.
In the CDP the population was spread out with 20.9% under the age of 18, 7.5% from 18 to 24, 27.1% from 25 to 44, 24.2% from 45 to 64, and 20.2% who were 65 years of age or older. The median age was 41 years. For every 100 females there were 92.1 males. For every 100 females age 18 and over, there were 86.4 males.
The median income for a household in the CDP was $23,810, and the median income for a family was $30,625. Males had a median income of $27,045 versus $17,500 for females. The per capita income for the CDP was $12,486. About 15.8% of families and 21.6% of the population were below the poverty line, including 39.1% of those under age 18 and 11.1% of those age 65 or over.