L-Citrulline is an amino acid that supports the body in optimizing blood flow through its conversion to L-arginine and then nitric oxide. Nitric oxide is involved in vasodilatation and low levels are associated with mental and physical fatigue and sexual dysfunction. L-Citrulline ( like L-Arginine and L-Ornithine), is a metabolite in the urea cycle and is involved in liver detoxification and vasodilatation pathways. It is produced in the urea cycle when carbamoyl phosphate is converted to L-Citrulline in the ornithine carbamoyl transferees reaction. When endogenous supplies of ornithine carbamoyl transferees are insufficient, supplemental L-Citrulline has been shown to support ammonia incorporation and liver detoxification of ammonia. Free form amino acid, high purity, well tolerated. For additional support, one may include Magnesium Malate Forte.
L-Citrulline was first isolated from watermelon. It was named after citrullus which is the latin for watermelon. It is a nonessential amino acid, which is not found in dietary protein. It is a precursor to the formation of L-Arginine and thus plays a vital role in Arginine recycling, which is an important factor in nitric oxide release.
It is one of the key elements to Nitric oxide creation that is unobserved. It is involved in the catabolism of the amino acid, L-Arginine. In bacteria, the arginine dihydrolase pathway deaminates arginine to citrulline and splits citrulline into ornithine and carbamoyl phosphate. This pathway is a source of energy for many microorganisms and is used as an identifying test.
Oral supplementation supply a readily accessible source of Citrulline for this purpose, and some current research further point out that Citrulline probably the best source of cellular Arginine. In addition it also increases energy, motivate the defense mechanism of body, and is fundamental for urea cycle function as well.
As a dietary supplement, 1 and 1/4 teaspoons two times daily, or as directed by a healthcare practitioner.
Contraindicated for individuals with kidney abnormalities, a hypersensitivity to L-citrulline and for children under 12 years of age.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, cure, mitigate, treat, or prevent any disease.