While Wapner noted that the transition to CMA from karyotyping in clinical practice will be gradual, as physicians and patients continue to be educated about its use, the two studies make the choice clear: "Why would anyone want to continue to use the standard method, which gives only part of the answer?" Dr. Wapner said in a statement published earlier this year by the
The larger of the two studies, entitled "Chromosomal Microarray Versus Karyotyping for Prenatal Diagnosis," enrolled 4,406 women. In 4,340 (98.8 percent) of the fetal samples, microarray analysis was successful. The second study, entitled "Karyotype Versus Microarray Testing for Genetic Abnormalities After Stillbirth," 532 stillbirths were analyzed. That study concluded that "microarray analysis is more likely than karyotype analysis to provide a genetic diagnosis, primarily because of its success with nonviable tissue, and is especially valuable in analyses of stillbirths with congenital anomalies…"
Both studies were funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development—part of the
In the case of stillbirths or miscarriages, especially when it happens more than once, "CMA can be used to determine if there is a genetic reason for these occurrences, and can give parents valuable information about future pregnancies," says Jessup.
Safe Harbor Statement under the Private Securities Litigation Reform Act of 1995
This press release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. These statements are based upon our current expectations, speak only as of the date hereof and are subject to change. All statements, other than statements of historical fact included in this press release, are forward-looking statements. Forward-looking statements can often be identified by words such as "anticipates," "expects," "intends," "plans," "goal," "predicts," "believes," "seeks," "estimates," "may," "will," "should," "would," "could," "potential," "continue," "ongoing," "objective," similar expressions, and variations or negatives of these words and include, but are not limited to, statements regarding the advantages and efficacy of CMA over standard karyotyping. These forward-looking statements are not
guarantees of future results and are subject to risks, uncertainties and assumptions that could cause our actual results to differ materially and adversely from those expressed in any forward-looking statement. The risks and uncertainties referred to above include, but are not limited to: market acceptance of CMA as a preferred method over karyotyping; the rate of transition to CMA from karyotyping; our ability to successfully expand the base of our customers and strategic partners, add to the menu of our diagnostic tests in both of our primary markets, develop and introduce new tests and related reports, optimize the reimbursements received for our testing services, and increase operating margins by improving overall productivity and expanding sales volumes; our ability to successfully accelerate sales, allow access to samples earlier in the testing continuum, steadily increase the size
of our customer rosters in both developmental medicine and oncology; our ability to attract and retain a qualified sales force; rapid technological change in our markets; changes in demand for our future products; legislative, regulatory and competitive developments; general economic conditions; and various other factors. Further information on potential factors that could affect our financial results is included in our Annual Report on Form 10-K, Quarterly Reports of Form 10-Q, and in other filings with the
CONTACT: Company Contact:
R. Judd JessupPresident & CEO, CombiMatrix CorporationTel (949) 753-0624 Investor Relations Contact: John BaldisseraBPC Financial Marketing Tel (800) 368-1217 Media Contact: Len HallVP, Media Relations Allen & CaronTel (949) 474-4300 firstname.lastname@example.org
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