Sam D Leary
Affiliation: University of Bristol
- Lack of emergence of associations between selected maternal exposures and offspring blood pressure at age 15 yearsSam D Leary
Lifecourse Epidemiology and Population Oral Health Research Group, School of Oral and Dental Sciences, University of Bristol, Bristol, UK
J Epidemiol Community Health 67:320-6. 2013..A recent review found little evidence for substantial effects of modifiable maternal exposures on offspring blood pressure (BP), but this may have been because almost all the studies reported on BP in early and mid-childhood...
- No evidence of large differences in mother-daughter and father-son body mass index concordance in a large UK birth cohortS Leary
Lifecourse Epidemiology and Population Oral Health Research Group, Department of Oral and Dental Science, University of Bristol, Bristol BS1 2LY, UK
Int J Obes (Lond) 34:1191-2. 2010..15 (0.12, 0.17) for males). Hence, our study suggests that there is no compelling reason to integrate the belief that there are large differences in parent-offspring body mass index associations with obesity prevention strategies...
- Physical activity and blood pressure in childhood: findings from a population-based studySam D Leary
Department of Oral and Dental Science, University of Bristol, 24 Tyndall Avenue, Bristol, BS8 1TQ UK
Hypertension 51:92-8. 2008..03 (95% CI -0.54, 0.48) mm Hg per 15 minutes/d MVPA. In conclusion, higher levels of PA were associated with lower BP, and results suggested that the volume of activity may be more important than the intensity...
- Maternal diet in pregnancy and offspring blood pressureS D Leary
Unit of Paediatric and Perinatal Epidemiology, Department of Community Based Medicine, University of Bristol, UK
Arch Dis Child 90:492-3. 2005....
- Geographical variation in neonatal phenotypeSam Leary
Diabetes Unit, King Edward Memorial Hospital, Pune, India
Acta Obstet Gynecol Scand 85:1080-9. 2006..Recent studies have shown associations between size and body proportions at birth and health outcomes throughout the life cycle, but there are few data on how neonatal phenotype varies in different populations around the world...
- Geographical variation in relationships between parental body size and offspring phenotype at birthSam Leary
Medical Research Council, Environmental Epidemiology Unit, University of Southampton, Southampton, UK
Acta Obstet Gynecol Scand 85:1066-79. 2006..Paternal size and body composition also play a role, primarily through the fetal genome, although few studies have investigated relationships with neonatal phenotype...
- Maternal diet in pregnancy and offspring height, sitting height, and leg lengthSam Leary
Unit of Paediatric and Perinatal Epidemiology, Department of Community Based Medicine, University of Bristol, 24 Tyndall Avenue, Bristol BS8 1TQ, UK
J Epidemiol Community Health 59:467-72. 2005..To examine the association between maternal diet in pregnancy and offspring height, sitting height, and leg length...
- Maternal smoking during pregnancy and offspring trajectories of height and adiposity: comparing maternal and paternal associationsLaura D Howe
MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK
Int J Epidemiol 41:722-32. 2012..Causality for obesity is not established. Causality is well-supported for birth length, but evidence on persistence of height deficits is inconsistent...
- Objectively measured physical activity and fat mass in a large cohort of childrenAndy R Ness
Department of Oral and Dental Science, University of Bristol, United Kingdom
PLoS Med 4:e97. 2007..Previous studies have been unable to characterise the association between physical activity and obesity, possibly because most relied on inaccurate measures of physical activity and obesity...
- Maternal anemia, iron intake in pregnancy, and offspring blood pressure in the Avon Longitudinal Study of Parents and ChildrenMarie Jo A Brion
MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Bristol, UK
Am J Clin Nutr 88:1126-33. 2008..Studies in pregnant women are limited in number, have had inconsistent results, and have not accounted for maternal iron supplementation...
- Smoking during pregnancy and offspring fat and lean mass in childhoodSam D Leary
Department of Community Based Medicine, University of Bristol, 24, Tyndall Avenue, Bristol, BS8 1TQ, United Kingdom
Obesity (Silver Spring) 14:2284-93. 2006..This study examined the association between maternal and partner smoking during pregnancy and offspring total fat, truncal fat, and lean mass in childhood...
- Similar associations of parental prenatal smoking suggest child blood pressure is not influenced by intrauterine effectsMarie Jo A Brion
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, United Kingdom
Hypertension 49:1422-8. 2007..36 to 0.87; P=0.4 fully adjusted), providing further evidence that differences in child blood pressure observed in minimally adjusted models are not because of a biological influence of maternal smoking on the intrauterine environment...
- Modifiable maternal exposures and offspring blood pressure: a review of epidemiological studies of maternal age, diet, and smokingMarie Jo A Brion
Department of Social Medicine, University of Bristol, Bristol BS8 2PR, United Kingdom
Pediatr Res 63:593-8. 2008..03 to 0.21, I = 89.8%). In sum, there is little empirical evidence that the maternal exposures reviewed program offspring BP. Other components of offspring health may be more susceptible to effects of programming in utero...
- Association between body composition and blood pressure in a contemporary cohort of 9-year-old childrenM A Brion
Department of Social Medicine, University of Bristol, Bristol, UK
J Hum Hypertens 21:283-90. 2007..In this analysis, because both fat and lean masses are associated with BP, BMI predicts BP at least as well as these components of body composition...
- Drawing causal inferences in epidemiologic studies of early life influencesAndy R Ness
School of Oral and Dental Sciences, Bristol Dental School, Bristol, United Kingdom
Am J Clin Nutr 94:1959S-1963S. 2011..These approaches to confounding often require the comparison of data from different populations or a combination of studies to ensure adequate power to provide robust estimates of the causal effect...
- Cross-sectional association between smoking depictions in films and adolescent tobacco use nested in a British cohort studyAndrea E Waylen
School of Oral and Dental Sciences, University of Bristol, Bristol BS1 2LY, UK
Thorax 66:856-61. 2011..To assess associations between exposure to smoking depictions in films and adolescent tobacco use in a British population cohort...
- Does birth weight predict childhood diet in the Avon longitudinal study of parents and children?W A Shultis
Department of Social Medicine, University of Bristol, Bristol, UK
J Epidemiol Community Health 59:955-60. 2005..Therefore, the objective of this study was to investigate associations between birth weight and childhood diet, and in particular, to test the hypothesis that birth weight is inversely related to total and saturated fat intake...
- Newborn size, infant and childhood growth, and body composition and cardiovascular disease risk factors at the age of 6 years: the Pune Maternal Nutrition StudyC V Joglekar
Diabetes Unit, King Edward Memorial Hospital, Rasta Peth, Pune 411011, India
Int J Obes (Lond) 31:1534-44. 2007..To study associations of size and body proportions at birth, and growth during infancy and childhood, to body composition and cardiovascular disease (CVD) risk factors at the age of 6 years...
- Maternal age in pregnancy and offspring blood pressure in childhood in the Avon Longitudinal Study of Parents and Children (ALSPAC)R J Roberts
1United Bristol Healthcare Trust, Bristol, UK
J Hum Hypertens 19:893-900. 2005..04, P = 0.5) for systolic BP and beta = -0.03 (95% CI -0.07 to 0.01, P = 0.2) for diastolic BP. We conclude that there is no evidence of a relationship between maternal age in pregnancy and childhood BP in this contemporary birth cohort...
- Diet in childhood and adult cardiovascular and all cause mortality: the Boyd Orr cohortA R Ness
Unit of Paediatric and Perinatal Epidemiology, University of Bristol, Bristol, UK
Heart 91:894-8. 2005..To examine the association between childhood diet and cardiovascular mortality...
- Haemoglobin A1c is not a surrogate for glucose and insulin measures for investigating the early life and childhood determinants of insulin resistance and Type 2 diabetes in healthy children. An analysis from the Avon Longitudinal Study of Parents and ChilW A Shultis
Department of Social Medicine, University of Bristol, UK
Diabet Med 23:1357-63. 2006..We investigated haemoglobin A(1c) (HbA(1c)), a marker of glycaemia measured in non-fasting blood, as an alternative...
- The effect of LRP5 polymorphisms on bone mineral density is apparent in childhoodM Audrey Koay
Institute of Musculoskeletal Sciences, University of Oxford, Botnar Research Centre, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford, OX3 7LD, UK
Calcif Tissue Int 81:1-9. 2007..These results indicate that LRP5 influences volumetric bone density in childhood, possibly through effects on trabecular bone formation...
- Objective measurement of levels and patterns of physical activityChris J Riddoch
Sport and Exercise Science, School for Health, University of Bath, Bath, UK
Arch Dis Child 92:963-9. 2007..To measure the levels and patterns of physical activity, using accelerometers, of 11-year-old children participating in the Avon Longitudinal Study of Parents and Children (ALSPAC)...