Post-treatment changes of colonic carcinoma
Reviewers: Charanjeet Singh, M.D. (see Reviewers page)
Revised: 15 October 2011, last major update September 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.
● Preoperative (neoadjuvant) radiation therapy, with or without chemotherapy, is often used to treat rectal adenocarcinoma
● Presence of acellular mucin reflects pretreatment tumor
● Flat, firm mass with central ulceration
● May be no identifiable lesion
● Regenerated mucosa at edge of ulcer
● Tumor cells with variable tumor effects of fibrosis, mucin pools, inflammation and necrosis
● Cytokeratin to detect rare residual tumor cells
End of Colon tumor > Carcinoma > Post-treatment changes of colonic carcinoma
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