3-Deoxy-glucosone is an Intermediate in the Formation of Furfurals from D-Glucose.
Article first published online: 29 JUN 2011
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 4, Issue 8, pages 1049–1051, August 22, 2011
How to Cite
Jadhav, H., Pedersen, C. M., Sølling, T. and Bols, M. (2011), 3-Deoxy-glucosone is an Intermediate in the Formation of Furfurals from D-Glucose. ChemSusChem, 4: 1049–1051. doi: 10.1002/cssc.201100249
- Issue published online: 22 AUG 2011
- Article first published online: 29 JUN 2011
- Manuscript Received: 17 MAY 2011
The acid-catalyzed dehydration of glucose to hydroxymethylfurfural (6) can occur via two possible mechanisms. 3-deoxy-D-erythro-hex-2-ulose (3) is found to be an intermediate in the formation of 6 from glucose (1). This finding implies that elimination of the glucose 3-OH group is the important step, rather than isomerization of the carbonyl group.