Dr Alex White - BSc PhD CChem MRSC
Member of the School's Medicinal Chemistry Research Discipline
Anti-cancer drug design
Structure-based drug design against various targets of interest including the DNA damage response, the EGFR-IGFR1 signalling pathway and the cell cycle. Several novel lead compounds have been identified that are currently undergoing further development.
We have successfully developed a novel co-drug for the treatment of psoriasis with improved therapeutic and topical delivery properties compared to current treatments for the disease.
We have been investigating natural products from Welsh marine organisms and have identified anti-cancer activity in extracts from Welsh sponges. Currently involved in isolation and characterisation of discrete biologically active molecules.