Making a Difference in Cancer Prevention and Control
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‘Not beyond us’, World Cancer Day 2015, takes a positive and proactive approach to the fight against cancer, highlighting that solutions do exist across the continuum of cancer. We are reminded that solutions are within our reach!
4 February 2015
World Cancer Day: Leagues Unite to Keep Cancer on the Political Agenda
The Association of European Cancer Leagues (ECL) warmly welcomes World Cancer Day, today, February 4th. Connecting cancer leagues across Europe and beyond, ECL is committed to the fight against cancer, and working together to ensure that cancer is ‘not beyond us’.
ECL is of the firm belief that strong European cancer policy can help strengthen national frameworks. A prime example is the 4th revision of the European Code against Cancer, launched in October 2014. The European Code against Cancer is a set of 12 evidence-based messages on actions that the individual can take to reduce his/her cancer risk, including not using tobacco, maintaining a healthy diet and body weight, participating in screening programmes, etc. This is an initiative funded by the European Commission and developed by the WHO's International Agency for Research on Cancer (IARC). This is a key tool not only to promote cancer prevention among European citizens, but also a tool to reduce health inequalities across the EU, as these messages apply to everyone in equal measures. The Code encourages political support, providing that "successful cancer prevention requires these individual actions to be supported by governmental policies and actions."
The President of the Association of European Cancer Leagues and Head of Nursing Services at the Irish Cancer Society, Joan Kelly, emphasises the need for comprehensive prevention policies in EU legislation. “Prevention is a crucial aspect in the long term management of the cancer epidemic. The EU must be active to emphasise the life choices people can make to reduce their risk of cancer. These range from well known messages such not using tobacco of any kind, maintaining a healthy diet and body weight, and also encouraging people to participate in screening programmes.
“The EU can be a game changer in promoting prevention policies across the member states. My hope this World Cancer day 2015 is that it inspires our European politicians to take action in the field of prevention, as the best way to protect citizens all across the EU 28 and the wider Europe.”
ECL leagues will endeavour, this World Cancer Day and all year round, to work together to keep cancer high on the policy agenda at the European and national level, and continue our efforts in health promotion and cancer control across all of Europe. Together, we can achieve our vision for a Europe Free of Cancers!
See recent IARC Press Release: Most types of cancer not due to "bad luck"
IARC responds to scientific article claiming that environmental and lifestyle factors account for less than one third of cancers
Lyon, France, 13 January 2015 - The International Agency for Research on Cancer (IARC), the World Health Organization's specialized cancer agency, strongly disagrees with the conclusion of a scientific report (1) on the causes of human cancer published in the journal Science on 2 January 2015 by Dr Cristian Tomasetti and Dr Bert Vogelstein.
Read the PRESS RELEASE HERE and below:
The study, which has received widespread media coverage, compares the number of lifetime stem cell divisions across a wide range of tissues with lifetime cancer risk and suggests that random mutations
(or "bad luck") are "the major contributors to cancer overall, often more important than either hereditary or external environmental factors."
For many cancers, the authors argue for a greater focus on the early detection of the disease rather than on prevention of its occurrence. If misinterpreted, this position could have serious negative
consequences from both cancer research and public health perspectives. IARC experts point to a serious contradiction with the extensive body of epidemiological evidence as well as a number of methodological limitations and biases in the analysis presented in the report.
"We already knew that for an individual to develop a certain cancer there is an element of chance, yet this has little to say about the level of cancer risk in a population," explains IARC Director Dr Christopher
Wild. "Concluding that 'bad luck' is the major cause of cancer would be misleading and may detract from efforts to identify the causes of the disease and effectively prevent it."
The past five decades of international epidemiological research have shown that most cancers that are frequent in one population are relatively rare in another and that these patterns vary over time (2).
For example, oesophageal cancer is common among men in East Africa but rare in West Africa. Colorectal cancer, once rare in Japan, increased 4-fold in incidence in just two decades. These observations are characteristic of many common cancers and are consistent with a major contribution of environmental and lifestyle exposures, as opposed to genetic variation or chance ("bad luck").
Furthermore, IARC experts identify several limitations in the report itself. These include the emphasis on very rare cancers (e.g. osteosarcoma, medulloblastoma) that together make only a small contribution to the total cancer burden. The report also excludes, because of the lack of data, common cancers for which incidence differs substantially between populations and over time. The latter category includes some of the most frequent cancers worldwide, for example those of the stomach, cervix, and breast, each known to be associated with infections or lifestyle and environmental factors. Moreover, the study focuses exclusively on the United States population as a measure of lifetime risk. The comparison of different populations would have yielded different results.
Although it has long been clear that the number of cell divisions increases the risk of mutation and, therefore, of cancer, a majority of the most common cancers occurring worldwide are strongly related to environmental and lifestyle exposures. In principle, therefore, these cancers are preventable; based on current knowledge, nearly half of all cancer cases worldwide can be prevented. This is supported in practice by rigorous scientific evidence showing decreases in cancer incidence after preventive interventions. Notable examples include drops in rates of lung cancer and other tobacco-related cancers after reductions in smoking and declines in hepatocellular carcinoma rates among people vaccinated against hepatitis B virus.
"The remaining knowledge gaps on cancer etiology should not be simply ascribed to 'bad luck'," says Dr Wild. "The search for causes must continue while also investing in prevention measures for those cancers where risk factors are known. This is particularly important in the most deprived areas of the world, which face a growing burden of cancer with limited health service resources."
(1) Tomasetti C, Vogelstein B (2015). Variation in cancer risk among tissues can be explained by the number of stem cell divisions. Science. 347(6217):78–81. http://dx.doi.org/10.1126/science.1260825
(2) Stewart BW, Wild CP, editors (2014). World Cancer Report 2014. Lyon, France: International Agency for Research on Cancer
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