Modern Methods of Organic Synthesis
The fourth edition of this well-known textbook discusses the key methods used in organic synthesis, showing the value and scope of these methods and how they are used in the synthesis of complex molecules. All the text from the third edition has been revised, to produce a modern account of traditional methods and an up-to-date description of recent advancements in synthetic chemistry since the previous edition. A new chapter on the functionalisation of alkenes has been included and greater emphasis on highly stereoselective reactions and radical chemistry has been placed. Reference style has been improved to include footnotes on each page, allowing easy and rapid access to the primary literature. The book will be of significant interest to chemistry and biochemistry students at advanced undergraduate and graduate level, as well as researchers in academia and industry who wish to familiarise themselves with modern synthetic methods.
What people are saying - Write a review
a.p-unsaturated acetate addition adduct aldehyde aldehyde or ketone aldol reaction alkaloid alkene alkenyl alkyl alkynes allylic alcohol amine anion aromatic asymmetric B. M. Trost borane boron carbon atom carbon-carbon carbonyl carbonyl compounds carbonyl group catalyst Chem chloride CO2Me complex conjugate converted cyclization cycloaddition cycloaddition reactions cyclopropane deprotonation derivatives diastereomer Diels-Alder reaction diene dienophile double bond electron electrophiles elimination enantioselectivity endo ene reaction enol ether epoxidation ester example Fleming formation formed functional groups gave give halides hydride hydroboration hydrogen atom imine intermediate intramolecular isomer ketone less-hindered Lewis acid lithium metal method methyl mixture nucleophilic obtained Organic Synthesis organoborane Oxford oxidation oxygen Pergamon Press prepared presence proton radical react reactive readily reagents rearrangement reduction regioselectivity ring salt selectivity silyl sodium solvent species stereoselectivity substituents substrate sulfone temperature Tetrahednm Tetrahedron trans transition tributyltin tributyltin hydride undergo unsaturated ylide Z-alkene