Cushing's disease results from an excess of adrenal gland hormones. It is a common side-effect of drugs like Prednisone, which is often prescribed to treat dog arthritis, allergies and other ailments. Cushing's disease can also result from a benign tumor on one of the adrenal glands or the pituitary gland.
Symptoms of Cushing's disease include:
- Increased thirst and appetite
- Frequent urination
- Loss of hair
- Skin problems
- High blood pressure
- Increased susceptibility to infections
If left untreated, Cushing's disease can lead to even worse conditions like diabetes and heart problems.
Traditional Western Therapies
Note: Your dog's Cushing’s could be caused by a corticosteroid drug such as Prednisone, it may be possible to wean your dog off the drug. You should speak to your vet about this. Prednisone sometimes has side effects that are worse than the condition it was used to treat, and makes your dog more susceptible to bacterial and viral infections. Every day, we get calls from customers looking for an alternative to Prednisone L-deprenyl (Anipryl) - for treatment of pituitary-dependent Cushing’s disease (PDH), especially in cases that are mild and when owners are unwilling to risk the adverse effects associated with mitotane or trilostane.
Mitotane (Lysodren) - During its evaluation as an insecticide, mitotane was discovered to have adrenocorticolytic effects. The most obvious and rapid response is a reduction in water intake, urine output, and appetite, which usually occur at the end of the initial course of therapy. Muscle strength and exercise tolerance improve over the first 3-4 weeks. Skin and hair coat changes take longer and the progress is variable. After the first re-evaluation, rechecks should be scheduled every 3-6 months for the rest of the pet’s life to determine whether the dose of mitotane needs to be adjusted depending on the results of ACTH response testing. Overall, based on the results of three survival studies, the mean survival time of treated dogs with pituitary-dependent Cushing’s disease is 24 to 30 months with a range of 1 day to 13 years.
Surgery - If your dog's Cushing's disease was caused by a tumor, surgery might be an option. Only your vet can answer this question.
Trilostane - Trilostane has been shown to be an effective treatment for canine and feline Cushing’s syndrome. Trilostane is a synthetic, orally active steroid analogue. It acts as a competitive inhibitor of the 3β-hydroxysteroid dehydrogenate enzyme system and thereby inhibits the synthesis of cortisol and aldosterone as well as other steroids. The blockade is reversible and appears to be dose related.
A word from our veterinarian:
It is important to note that long-term use of corticosteroid drugs (usually prescribed for inflammatory discomfort such as skin allergy or arthritis) can result in a rebound effect and excess production of cortisol by the adrenal glands can ensue. Another cause of excessive cortisol can be a tumor, either of the pituitary or the adrenals.
Adrenal Harmony Gold was developed by our holistic veterinarians with the middle-aged and older pet in mind - when increased support for the adrenals can be helpful. The herbal actions in Adrenal Harmony Gold are: adaptogenic, antioxidant and will support the nervous system. These herbs are particularly suited to supporting the adrenal glands and its functions. "Adaptogens" are a group of herbs considered to nourish and balance the adrenals, helping the body adapt naturally and have normal levels of energy. Antioxidants counter oxidative (free radical) damage that can lead to degeneration.
Together, the ingredients in Adrenal Harmony Gold target the body systems that help to keep the adrenal and anterior pituitary hormones in a healthy and normal balance. They also contribute to the body's healthy stress response for normally calm moods and sleep.
What is Adrenal Harmony Gold used for?
Adrenal glands play a vital role in the health of your pet. The adrenal glands are two small glands situated on top of each kidney and they are involved in a multitude of body processes. The hypothalamus and pituitary glands are responsible for sending messages to the adrenals so they can secrete the right amount of hormones and maintain equilibrium within the body.
Some of the main adrenal gland functions are to:
- Help the body respond to stress and inflammation through their production of corticosteroid hormones.
- Play an important role in regulating water and electrolyte balance (affects urine output and thirst).
- Produce hormones that affect blood sugar (affects appetite).
Adrenal Harmony Gold targets the HPA axis (hypothalamus-pituitary-adrenal) to strengthen the body's internal feedback mechanisms. This in turn, can affect areas of the body influenced by the adrenal glands.
Can my dog take Adrenal Harmony Gold with prescription drugs?
Do not give Adrenal Harmony Gold if your pet is taking blood-thinners. A veterinarian who has performed a complete medical check of your dog can help to establish safety of prescription drugs taken with other products or specific diets.
"My 11 year old Lab had been on Cushing meds for 1 ½ months and was getting worse – at first she seemed to be doing ok, but then started to really deteriorate. I did some research and realized the cure might be as bad as the disease. Then I looked for alternatives for Cushings and found this website and read how other animals did with this Adrenal Harmony. About two months ago I decided to give it a try as I was losing hope anyway. Am I ever glad I did and I am happy to say she is doing way better and has returned to her happy self. Her tummy looks better, she is eating better, she is urinating less, her energy and attitude are way better. I would encourage anyone to give it a try!"
— Tom from Concord CA
- Promotes healthy skin and coat
- Helps normal hair growth
- Supports normal thirst and urination
- Supports healthy weight, normal appetite
- Supports proper muscle tone
Guaranteed to Help Your Dog
- 1 bottle = 2oz (59ml) a 1 month supply for most dogs (up to 50lbs)