Tag: "formation" at biology news
First 'atlas' of key brain genes could speed research on cancer, neurological diseases
...pivotal role in brain development by direction the formation
of neurons and supporting cells called glia from u...particular transcription factor is involved in the formation
of some specific kind of cell." Stiles is pursuing TF's that direct the formation
of astrocytes, whi...
Mouse brain tumors mimic those in human genetic disorder
...mmune system cells may be essential to the initial formation
of tumors and therefore may be promising drug targ...me gene. Their latest paper shows that brain tumor formation
in these mice has several of the same distinguishing clinical characteristics as tumor development i...
Scientists identify molecular events that drive cell senescence
...ulators of chromatin structure, play a key role in formation
of SAHF. When human cells were genetically manipul...it and support the notion that HIRA/ASF1a-mediated formation
of SAHF directly contributes to cell cycle exit during senescence," concludes Dr. Adams. The researc...
Fox Chase Cancer Center scientists discover key proteins linked to aging and cancer
...east three proteins in the cell that contribute to formation
of SAHF. These are called HIRA, ASF1a and PML.Of ...ts have known for sometime that PML suppresses the formation
of this cancer, but no one knew why. Adams' work suggests the possibility that this cancer arises be...
JCI table of contents, 3 January 2005
...erative retinopathy, characterized by the abnormal formation
of blood vessels in the retina, is a major cause o...ion and preventing cell reproduction. However, the formation
and accumulation of MTX polyglutamates (MTXPGs) within cells can be toxic. In the January 3 issue of...
Study examines relationship of vitamin A pathway to breast tumor progression
...egies to determine how retinoids may prevent tumor formation
and growth of both hormone receptorpositive and negative breast cancers....
Zebrafish may hold key to understanding human nerve cell development
...unicate with each other and even influence synapse formation
between neurons. Piotrowski's research in zebrafish focuses on the development of sensory neurons known as hair cells. Like humans, zebrafish use hair cells to detect sound and motion. However, in humans hair cells are buried deep inside the in...
Pitt scientists study how cancer cells get out of control
...in can cause changes in a cell associated with the formation
of tumors. "Virtually all cancer cells acquire the...etic material, uncontrolled cell division, and the formation
of tumors. Why this doesn't always happen when there are too many centrosomes was the focus of the ...
No blind mice, thanks to UF scientists
...plain how they used a common antibody to block the formation
of SDF-1 in the eyeballs of mice with simulated retinopathy, ending the explosive blood vessel growth that characterizes the condition. Researchers effectively silenced SDF-1's signal to activate normally helpful blood stem cells, which become too m...
Queen's discovery sheds new light on ancient temperatures
... ice ages that left the oceans cold enough for the formation
of this mineral? One controversial theory known as "The Snowball Earth" hypothesis suggests that around 700 million years ago the earth was almost totally enclosed in ice. The Queen's discovery offers alternatives to this hypothesis. Glaciers wax an...
In Nature paper, scientists at U.Va. health system crack part of 'histone' code
...chemical modification of histones may underlie the formation
of certain cancers. "This research adds important knowledge to our understanding of how cells signal to turn genes on," Grant said. Contributors to the research in Nature with Grant were Marilyn G. Pray-Grant and Jeremy A. Daniel, both of the De...
New drug may aid battle against nicotine addiction, Alzheimer's and other disorders
...pecific drugs. These behaviors all result from the formation
of new connections between individual neurons or modifications of existing connections in the brain. "Imaging of nicotine receptors also gives us the potential to study why some people are more addicted to nicotine than others," Mukherjee said....
Reduced calorie and carbohydrate diet slows progression of Alzheimer's disease in mouse model
...genic -amyloid peptides in the brain, resulting in formation
of amyloid plaques which are known to be the fundamental problem in Alzheimer' disease. Of the mice fed ad-libitum, 100% developed these plaques. No plaque development was detected in the mice fed a carbohydrate and calorie restricted diet. The diet...
Tips from the journals of the American Society for Microbiology
...d on the human scalp, is often associated with the formation
of dandruff. Current methods of treatment consist...re we describe a novel approach for preventing the formation
of dandruff by inhibition of M. furfur with antibodies," say the researchers. (E. Dolk, M. van d...
Blood test shows promise as monitor for antiangiogenic cancer therapy
...erapies. Antiangiogenic cancer therapy targets the formation
of new blood vessels used to support tumor growth....ass of specific blood cells that contribute to the formation
of tumor vessels provide any useful information about the effectiveness of angiogenesis inhibitors. ...
New cancer gene identified by Memorial Sloan-Kettering scientists
...e Pokemon protein plays such a crucial role in the formation
of cancer, it could prove to be an effective target for new drug therapies." Pokemon works by controlling the pathways that are required to transform normal cells to cancerous ones. The researchers found that when they "knocked out" the Pokemon gene ...
Spleen may be source of versatile stem cells
... key steps in embryonic development including the formation
of the spleen but it was not known to be present in adults under normal circumstances. In some other animals, however, the protein has an intriguing function: when creatures like newts regenerate a lost limb or tail, production of Hox11 is radical...
Key molecule in plant photo-protection identified
... found that intense exposure to light triggers the formation
of zeaxanthin molecules which are able to interact...trains of Arabidopsis thaliana clearly showed that formation
of zeaxanthin and its charge exchange with chlorophyll were responsible for the energy quenching we ...
A new New Year's reason to work out: Exercise improves three measures of heart protection
... that exercisers may be better able to prevent the formation
of blood clots, and may be one reason why exercisers are less likely to have heart attacks. Next steps The authors note that although the correlations in the study between general fitness and healthy blood clotting measurements are very strong, t...
How do cells travel through our bodies?
...l along tissues. This behavior is essential to the formation
of an embryo and other processes, but it must be t... small group of cells is crucial occurs during the formation
of an animal embryo. As the brain and head begin to take shape, a group of cells multiplies to form ...
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