C. Elegans ageing and cell division
cummins at possum.murdoch.edu.au
Wed Dec 22 21:42:40 EST 1993
In article <CIG9M3.Kw0.2 at cs.cmu.edu>
tsf at CS.CMU.EDU (Timothy Freeman) writes:
> Don't muscle cells divide when people do body building to get bigger muscles?
Muscle grows by hypertophy, not hyperplasia. Mitosis has been observed
in rare circumstances in the vicinity of injured intestine and stomach.
Regeration of injured skeletal muscle is thought to take place by
recruitment of nuclei from adjacent living fibers, bu t this is not
part of normal growth and development. This makes muscle a prime
target for age-related damage through mitochondrial dysfunction
(deletion/mutation accumulation) and free radicals.
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