Latest Polyomavirus Stories
ATLANTA, Aug. 16, 2011 /PRNewswire/ -- Inhibikase Therapeutics, Inc., an emerging leader in infectious disease, announced today that it has received FDA clearance to commence a Phase II proof-of-concept trial for its lead compound IkT-001.
The JC polyomavirus doesn't strike very often, but when it does, this mean bug can leave a devastating path.
The JC polyomavirus doesn't strike very often, but it's a mean bug that preys on people with weakened immune systems, including people with AIDS, and almost always kills them.
SAN DIEGO, Oct. 26 /PRNewswire/ -- Inhibikase Therapeutics, a specialty pharmaceutical company based in Atlanta, Georgia, will discuss simultaneous antiviral and antibacterial activity from small molecule agents at the 2009 BIOCOM Investor Conference.
The Merkel cell polyomavirus (MCPyV) is the only human polyomavirus known to be associated with a rare skin cancer, known as Merkel cell carcinoma, according to a new study published online September 23 in the Journal of the National Cancer Institute.
A new and simple urine test can detect polyomavirus nephropathy, a relatively new and serious complication that affects up to 9% of kidney transplant recipients.
By Valle, Luis Del White, Martyn K; Khalili, Kamel Abstract The human polyomavirus JC (JCV) is a small DNA tumor virus and the etiologic agent of the progressive multifocal leukoencephalopathy.
By Shishido-Hara, Yukiko Higuchi, Kayoko; Ohara, Sinji; Duyckaerts, Charles; Hauw, Jean-Jacques; Uchihara, Toshiki Abstract Progressive multifocal leukoencephalopathy is a fatal demyelinating disorder due to human polyomavirus JC infection in which there are viral inclusions in enlarged nuclei of infected oligodendrocytes.
By McCalmont, Vicki Bennett, Kristi Progressive multifocal leukoencephalopathy is a rare, highly fatal demyelinating brain infection caused by the JC virus. This infection is associated with immunosuppressive agents and is emerging in the transplant population.
Polyomavirus is the sole genus of viruses within the family Polyomaviridae. Ludwik Gross discovered the first polyomavirus, Murine polyomavirus, in 1963. Many polyomaviruses infect birds and mammals and have been extensively studied as tumor viruses in humans and animals. Polyomaviruses are DNA-based, small, and icosahedral in shape. They can potentially cause tumors and often persist as latent infections in a host without causing disease. There are three major clades or...
Merkel cell polyomavirus (MCV or MCPyV), first discovered in January 2008, is one of seven human tumor viruses. It is suspected to cause most of Merkel cell carcinoma which is a rare, aggressive form of skin cancer. Around 80% of Merkel cell carcinoma tumors are found to be infected with MCV. It is found in respiratory secretions suggesting that it may be transmitted by a respiratory route. Usually the tumors with MCV viruses go through at least two mutations that render the virus...
The BK virus, a member of the polyomavirus family, has no major consequences of infected except with those that are immunocomprimised or immunosuppressed. The virus was first isolated in 1971 from the urine sample of a renal transplant patient whose initials were B.K. Similar in genome sequences to the JCV virus they are most easily identified and differentiated from each other through serological tests using specific antibodies or through PCR based genotyping approach. Most people are...