FAM5C expression is modulated by the T allele of rs10920501. Eighty-eight human donor aorta were harvested, genotyped for rs10920501, and assayed for FAM5C expression using Affy tag 34442_at. Box plots are shown for gene expression by genotype. The presence of the T allele of rs10920501 significantly reduces FAM5C expression. The p-value shown is for the generalized model adjusted for age, sex, and race. * n = 1 in the TT genotype group.
Connelly et al. BMC Medical Genetics 2008 9:33 doi:10.1186/1471-2350-9-33