This really comes from an ancient Chinese novel. Imagine during the PCs' travels, they come to a place where the gender roles are completely reversed. What adventures will the PCs encounter in such a place?
A sentiment weapon that is very impressionable in terms of what is right and wrong, akin to a child. Currently, being ownerless, it is not very powerful. However, once it has found an owner, it can provide significant boosts to the wielder in an area or areas the wielder most desire. What adventures will this sentiment weapon go through? How will it develop itself in terms of power and personality?
Often times in when alchemy is thought of, we think medieval times with wizards and sorcerers. What if such things existed in modern days such as today? What if the focus of alchemy is common knowledge is can be used for favorite drinks? What if you have a soda machine that can create soda with special properties? The varieties is endless, though good taste is limited. What kind of concoctions can you create?